Anti-Human IFNAR1 Recombinant Antibody

Name: Anti-Human IFNAR1 Recombinant Antibody
SKU: TAB-379CL
Rating: 5 (1 reviews)

CAT#: TAB-379CL

Recombinant Humanized monoclonal antibody expressed in CHO binding to Human IFNAR1. The humanized monoclonal antibodiess which bind to IFNAR-1 are using for therapy of Celiac Disease, Crohn's Disease, and Ulcerative Colitis (collectively referred to as Inflammatory Bowel Disease, or IBD).

Gene Expression

Normal Tissue Figure 1 Cerebral cortex

Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_B_9_5.jpg

Normal Tissue Figure 2 Testis

Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_4_6.jpg

Normal Tissue Figure 3 Lymph node

Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_9_8.jpg

RNA Expression Figure 4 RNA cell line category: Cell line enhanced (Karpas-707)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1

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Specifications

Derivation
Humanized

Type
Antibody

Species Reactivity
Human

Related Disease
Crohn's Disease; Ulcerative Colitis

Product Property

Purity
>95%, by SDS-PAGE with Coomassie Brilliant Blue staining

Storage
Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.

Target

Alternative Names
IFNAR1; interferon (alpha, beta and omega) receptor 1; AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; interferon alpha/beta receptor 1; CRF2-1; IFN-R-1; IFN-alpha/beta receptor 1; interferon-beta receptor 1; beta-type antiviral protein; alpha-type antiviral prot

Gene ID
3454

UniProt ID
P17181

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-379CL.pdf

MSDS

MSDS - TAB-379CL.pdf

COA

Certificate of Analysis Lookup

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