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    Anti-Human IL-1R1 Recombinant Antibody Fab Fragment (TAB-215CT-F(E)) (CAT#: TAB-215CT-F(E))

    Recombinant monoclonal antibody to interleukin-1 receptor 1. It is a human antibody intended for the prophylaxis and treatment of rheumatoid arthritis, asthma and chronic obstructive pulmonary disease (COPD).

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line ASC TERT1
    Figure 1 IF staining of human cell line ASC TERT1
    (Immunofluorescent staining of human cell line ASC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1237/1774_H4_18_cr5952945990756_selected.jpg
    Figure 2 IF staining of human cell line U-2 OS
    Figure 2 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7779/211_A1_3_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human small intestine
    Figure 3 IHC staining of human small intestine
    (Immunohistochemical staining of human small intestine shows strong luminal membranous positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/29560/ihc_selected.jpg
    Figure 4 Testis
    Figure 4 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_6_6.jpg
    Figure 5 Lymph node
    Figure 5 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_8.jpg
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_B_8_5.jpg
    Figure 7 Colon
    Figure 7 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_3.jpg
    Figure 8 Liver
    Figure 8 Liver
    (Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_9_4.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HHSteC, HSkMC)
    Figure 9 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HHSteC, HSkMC)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115594-IL1R1

    Specifications

    • Host Species
    • Human
    • Type
    • Human antibody
    • Specificity
    • Human
    • Species Reactivity
    • Cynomolgus monkey,human
    • Applications
    • Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Blocking
    • Related Disease
    • Rheumatoid arthritis, Asthma, Chronic obstructive pulmonary disease (COPD)

    Target

    • Alternative Names
    • This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "IL1R1"

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    Please select product type
    Immunotoxin Products Human Antibody Products ADCC Enhanced Antibody Products Single Domain Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products ScFv Antibody Products Fab Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    AGTO-L026P anti-IL1R1 immunotoxin TP3 (IgG)-PAP Cytotoxicity assay, Functional assay

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    For Research Use Only. Not For Clinical Use.

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