This immunotoxin was achieved by conjugating/fusing the Anti-IL1R1 monoclonal antibody to Pokeweed antiviral protein. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to osteosarcoma cells and the toxin enters cells by receptor-mediated endocytosis. Then PAP is introduced into the cytoplasm where it eventually causes cell death by inactivating ribosomes. It was designed for treatment of osteosarcoma.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
AFC-392CL | Afuco™ Anti-IL1R1 Recombinant Antibody (AFC-392CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-213CT | Human Anti-IL1R1 Recombinant Antibody (TAB-213CT) | ELISA, BL | Human IgG |
TAB-214CT | Human Anti-IL1R1 Recombinant Antibody (TAB-214CT) | ELISA, BL | Human IgG |
TAB-215CT | Anti-Human IL-1R1 (interleukin-1 receptor 1) Recombinant Antibody (6GL) | ELISA, BL | Human antibody |
TAB-220CT | Human Anti-IL1R1 Recombinant Antibody (TAB-220CT) | ELISA, Inhibion, BL, IB | Human IgG |
TAB-213CT-S(P) | Human Anti-IL1R1 Recombinant Antibody; scFv Fragment (TAB-213CT-S(P)) | ELISA, BL | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-216CT | Anti-Human IL-1R1 (Interleukin 1 receptor type 1) Therapeutic Single Domain Antibody (DOM4-130) | Inhib | Single domain antibody |
TAB-217CT | Anti-Human IL-1R1 (Interleukin 1 receptor type 1) Therapeutic Single Domain Antibody (D0M4-130-46) | ELISA | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0953CT | Recombinant Mouse anti-Human IL1R1 Monoclonal antibody (732229) | ELISA, ICC/IF, RIA | |
HPAB-1862-FY | Human Anti-IL1R1 Recombinant Antibody (clone 26F5) | Inhib, Block | Human IgG1 |
HPAB-1863-FY | Human Anti-IL1R1 Recombinant Antibody (clone 15C4) | Inhib, Block | Human IgG1 |
HPAB-1864-FY | Human Anti-IL1R1 Recombinant Antibody (clone 27F2) | Inhib, Block | Human IgG1 |
VS3-QX596 | Mouse Anti-IL1R1 Recombinant Antibody (clone D12-D2) | WB, FC, ELISA | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1293CQ | Hamster Anti-Il1r1 Recombinant Antibody (clone JAMA147) | Neut | Hamster IgG |
NEUT-1294CQ | Rat Anti-Il1r1 Recombinant Antibody (clone CBL936) | ELISA, IP, Neut, WB | Rat IgG1 |
NEUT-1295CQ | Rat Anti-Il1r1 Recombinant Antibody (clone CBL937) | Neut, WB | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1799 | Rabbit Anti-IL1R1 Recombinant Antibody (clone DS1799AB) | WB, FC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1862-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 26F5); scFv Fragment | ELISA | Human scFv |
HPAB-1863-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 15C4); scFv Fragment | ELISA | Human scFv |
HPAB-1864-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 27F2); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1862-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 26F5); Fab Fragment | ELISA | Human Fab |
HPAB-1863-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 15C4); Fab Fragment | ELISA | Human Fab |
HPAB-1864-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 27F2); Fab Fragment | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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