Anti-human IL21R scFv Fragment (18G4)

Name: Anti-human IL21R scFv Fragment (18G4)
SKU: TAB-590LC-S(P)
Rating: 5 (1 reviews)

CAT#: TAB-590LC-S(P)

Recombinant monoclonal antibody 18G4 is a human antibody that specifically binds to human IL-21R and can be potentially used in the treatment of inflammatory arthritis and transplant rejection.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/if_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_7_5.jpg

Normal Tissue Figure 3 Colon

Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_3.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_5.jpg

Normal Tissue Figure 5 Testis

Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_6_6.jpg

Normal Tissue Figure 6 Bone marrow

Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_B_6_4.jpg

Normal Tissue Figure 7 Lymph node

Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42296/94512_A_8_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, RH-30, RPMI-8226, U-266/70)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103522-IL21R

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Specifications

Host Species
Human

Derivation
Antibody phagemid library

Type
Human antibody

Specificity
Human

Clone
18G4

Applications
ELISA, FC

Related Disease
Arthritis and transplant rejection

Target

Alternative Names
IL21R; interleukin 21 receptor; NILR; CD360; interleukin-21 receptor; IL-21 receptor; novel interleukin receptor

Gene ID
50615

UniProt ID
Q9HBE5

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-590LC-S(P).pdf

MSDS

MSDS - TAB-590LC-S(P).pdf

COA

Certificate of Analysis Lookup

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