Mouse Anti-IL23A Recombinant Antibody (clone HNU2319) (CAT#: NEUT-1335CQ)
This antibody is a mouse monoclonal antibody that binds specifically to IL-23 p19, and it can neutralize the bioactivity of IL-23 p19.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/if_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells in and outside germinal center.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_5_8_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells in and outside germinal center.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_5_8_selected.jpg
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/60_H7_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/60_H7_1_blue_red_green.jpg
Figure 4 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_9_3.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_9_3.jpg
Figure 5 Testis
(Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_5_6.jpg
(Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_5_6.jpg
Figure 6 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_8_8.jpg
(Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1554/4856_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110944-IL23A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110944-IL23A
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human IL23A
- Species Reactivity
- Human
- Clone
- HNU2319
- Applications
- FuncS, Neut
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL23A; interleukin 23; alpha subunit p19; P19; SGRF; IL-23; IL-23A; IL23P19; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six; G-CSF related factor
- Gene ID
- 51561
- UniProt ID
- Q9NPF7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single-domain Antibody
Recombinant Antibody
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Mouse Antibody
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Rabbit Monoclonal Antibody
Fab Fragment Antibody
ADCC Enhanced Antibody
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1953-VHH | Recombinant Anti-human IL23A VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
| TAB-005LC-VHH | Anti-human IL23A Recombinant Antibody (TAB-005LC-VHH) | ELISA | Single domain antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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