This product is a human recombinant monoclonal antibody, which targets the interleukin 23 subunit alpha (IL23A). Binding of this antibody to IL-23A as measured by SPR and the Kd value is 0.86 nM. It specifically binds to human IL-23A and it can be potentially used in the research of psoriasis, Crohn's disease and multiple sclerosis.
Figure 1 A series of graphical representations showing binding of humanized forms of E11E7 to IL-23 but not significantly binding to IL-12p40 or IL-23p19.
Blank refers to assay conditions in which the coating antigen is omitted.
Figure 2 Antibodies 1-4,6-22, 8-22, 20-4, 9-22 and 21-4 were tested for binding to IL-23 with ELISA.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1953-VHH | Recombinant Anti-human IL23A VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
TAB-005LC-VHH | Anti-human IL23A Recombinant Antibody (119A3) (TAB-005LC-VHH) | ELISA | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1642z | Mouse Anti-IL23A Recombinant Antibody (clone 2C10) | WB, ELISA, FC, IHC | Mouse IgG1 |
HPAB-AP118-YC | Mouse Anti-IL23A Recombinant Antibody (HPAB-AP118-YC) | ELISA | Mouse IgG |
HPAB-AP119-YC | Mouse Anti-IL23A Recombinant Antibody (HPAB-AP119-YC) | ELISA | Mouse IgG |
HPAB-AP120-YC | Mouse Anti-IL23A Recombinant Antibody (HPAB-AP120-YC) | ELISA | Mouse IgG |
HPAB-AP122-YC | Human Anti-IL23A Recombinant Antibody (HPAB-AP122-YC) | ELISA, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-420CL | Anti-Human IL23A Recombinant Antibody (BI 655066) | FuncS | Antibody |
TAB-613LC | Anti-human IL23A Recombinant Antibody (ST883/885) (TAB-613LC) | ELISA | Human antibody |
TAB-613LC-S(P) | Anti-human IL23A scFv Fragment (ST883/885) | ELISA | Human antibody |
TAB-622LC-S(P) | Human Anti-IL23A Recombinant Antibody; scFv Fragment (TAB-622LC-S(P)) | ELISA | Human scFv |
TAB-008ML | Anti-Human IL23A Recombinant Antibody (Brazikumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG2, λ |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBW-082 | Human Anti-IL23A Recombinant Antibody; scFv Fragment (PSBW-082) | Neut | Human scFv |
HPAB-655-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody (clone 8C92H6); scFv Fragment | ELISA | Mouse scFv |
HPAB-656-FY-S(P) | Human Anti-IL23A Recombinant Antibody (clone A5M20); scFv Fragment | Inhib | Humanized scFv |
HPAB-0860-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-0860-FY-F(E)) | Inhib | Mouse Fab |
HPAB-0861-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-0861-FY-F(E)) | Inhib | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-607LC | Anti-human IL23A Recombinant Antibody (E11E7Chimera) (TAB-607LC) | ELISA, Neut, FuncS | Chimeric antibody (rat/human) |
TAB-607LC-S(P) | Anti-human IL23A scFv Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
TAB-607LC-F(E) | Anti-human IL23A Fab Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-614LC | Anti-human IL23A Recombinant Antibody (8C9) (TAB-614LC) | ELISA, Inhib | |
TAB-615LC | Anti-human IL23A Recombinant Antibody (2H6) (TAB-615LC) | ELISA, Inhib | |
TAB-621LC | Mouse Anti-IL23A Recombinant Antibody (TAB-621LC) | ELISA, WB, Neut | Mouse IgG |
TAB-606LC-S(P) | Anti-human IL23A scFv Fragment (E11E7) | ELISA | |
TAB-606LC-F(E) | Anti-human IL23A Fab Fragment (E11E7) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-605LC-F(E) | Anti-human IL23A Fab Fragment (FM303) | ELISA | Humanized antibody |
TAB-608LC-F(E) | Anti-human IL23A Fab Fragment (21-4) | ELISA | Humanized antibody |
TAB-609LC-F(E) | Anti-human IL23A Fab Fragment (8-22) | ELISA | Humanized antibody |
TAB-610LC-F(E) | Anti-human IL23A Fab Fragment (6-22) | ELISA | Humanized antibody |
TAB-611LC-F(E) | Anti-human IL23A Fab Fragment (1-4) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1335CQ | Mouse Anti-IL23A Recombinant Antibody (clone HNU2319) | FuncS, Neut | Mouse IgG1, κ |
NEUT-1336CQ | Rabbit Anti-IL23A Recombinant Antibody (VMC198) | WB, Neut | Rabbit IgG2b |
NEUT-1337CQ | Human Anti-IL23A Recombinant Antibody (clone CBL1018) | Neut | Human IgG1, κ |
NEUT-1338CQ | Mouse Anti-IL23A Recombinant Antibody (clone M066) | Neut | Mouse IgG1 |
NEUT-1339CQ | Mouse Anti-Il23a Recombinant Antibody (clone CBL1028) | Neut | Mouse IgG2b, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4335 | Rabbit Anti-IL23A Recombinant Antibody (clone SI424DS) | ELISA | Rabbit IgG |
MOR-4615 | Rabbit Anti-IL23A Recombinant Antibody (clone TH128DS) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0516-CN-F(E) | Human Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-0516-CN-F(E)) | ELISA, FC, Neut | Human Fab |
HPAB-0517-CN-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-0517-CN-F(E)) | ELISA, FC | Mouse Fab |
HPAB-0518-CN-F(E) | Human Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-0518-CN-F(E)) | ELISA, FC | Humanized Fab |
HPAB-655-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody (clone 8C92H6); Fab Fragment | ELISA | Mouse Fab |
HPAB-656-FY-F(E) | Human Anti-IL23A Recombinant Antibody (clone A5M20); Fab Fragment | Inhib | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-875 | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Tildrakizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
AFC-TAB-620LC | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Risankizumab), ADCC Enhanced | ELISA | ADCC enhanced antibody |
AFC-TAB-008ML | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Brazikumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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