Human Anti-MADCAM1 Recombinant Antibody (clone PF-547659); Fab Fragment (CAT#: PFBL-636)
Recombinant Human Antibody (PF-547659) is capable of binding to MAdCAM-1 D1D2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-MAdCAM-1 D1D2 fab and CH1-3 region of human fab and a light chain (LC) encoding VL from anti-MAdCAM-1 D1D2 proteins fab and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human appendix
(Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/77998/169642_A_3_2_selected.jpg
(Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/77998/169642_A_3_2_selected.jpg
Figure 2 Appendix
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_2_2_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_2_2_val_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_8_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_7_4.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HEK93, Hep G2, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000099866-MADCAM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000099866-MADCAM1
Specifications
- Immunogen
- Human mucosal vascular addressin cell adhesion molecule 1
- Host Species
- Human
- Derivation
- Human
- Type
- Human Fab
- Specificity
- Human MADCAM1
- Species Reactivity
- Human
- Clone
- PF-547659
- Applications
- WB, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MACAM1; MADCAM1; mucosal vascular addressin cell adhesion molecule 1
- Gene ID
- 8174
- UniProt ID
- Q13477
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1935z | Mouse Anti-MADCAM1 Recombinant Antibody (MOB-1935z) | IHC, IF, ELISA | Mouse IgG2a |
| HPAB-0040-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0040-DJB) | ELISA | Human IgG2, κ |
| HPAB-0041-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0041-DJB) | ELISA | Human IgG4, κ |
| HPAB-0042-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0042-DJB) | ELISA | Human IgG4, κ |
| HPAB-0178-FY | Human Anti-MADCAM1 Recombinant Antibody (clone 7.16.6_S) | FC | Human IgG2, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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