Mouse Anti-MADCAM1 Recombinant Antibody (clone 10G3) (CAT#: PABL-640)
Recombinant Mouse Antibody (10G3) is capable of binding to MAdCAM-1 D1D2.
Specific Inquiry
Figure 1 Structure analysis of MAdCAM-Fab interfaces.
A, MAdCAM complex with 10G3 Fab. B, MAdCAM complex with PF-547659 Fab. Heavy chain is cyan; light chain is pink, and MAdCAM D1 is orange. Side chains and main chain atoms in the interfaces and the integrin binding loop of MAdCAM are in stick. MAdCAM Gly residues 40 and 46 have Cα spheres. Dashed lines show hydrogen bonds across the interfaces.
Yu, Y., Zhu, J., Huang, P. S., Wang, J. H., Pullen, N., & Springer, T. A. (2013). Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop. Journal of Biological Chemistry, 288(9), 6284-6294.
Specifications
- Immunogen
- Human mucosal vascular addressin cell adhesion molecule 1
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MADCAM1
- Species Reactivity
- Human
- Clone
- 10G3
- Applications
- WB, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MACAM1; MADCAM1; mucosal vascular addressin cell adhesion molecule 1
- Gene ID
- 8174
- UniProt ID
- Q13477
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1935z | Mouse Anti-MADCAM1 Recombinant Antibody (MOB-1935z) | IHC, IF, ELISA | Mouse IgG2a |
| PABL-641 | Human Anti-MADCAM1 Recombinant Antibody (clone PF-547659) | WB, IF, FuncS | Human IgG |
| HPAB-0178-FY | Human Anti-MADCAM1 Recombinant Antibody (clone 7.16.6_S) | FC | Human IgG2, κ |
| HPAB-692-FY | Mouse Anti-MADCAM1 Recombinant Antibody (HPAB-692-FY) | ELISA | Mouse IgG |
| VS4-CJ24 | Recombinant Rabbit Anti-MADCAM1 Antibody (clone 12B5) | ELISA, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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