Mouse Anti-MADCAM1 Recombinant Antibody (clone 10G3)
CAT#: PABL-640
Recombinant Mouse Antibody (10G3) is capable of binding to MAdCAM-1 D1D2.
Published Data
Gene Expression
Figure 1 Structure analysis of MAdCAM-Fab interfaces.
A, MAdCAM complex with 10G3 Fab. B, MAdCAM complex with PF-547659 Fab. Heavy chain is cyan; light chain is pink, and MAdCAM D1 is orange. Side chains and main chain atoms in the interfaces and the integrin binding loop of MAdCAM are in stick. MAdCAM Gly residues 40 and 46 have Cα spheres. Dashed lines show hydrogen bonds across the interfaces.
Yu, Y., Zhu, J., Huang, P. S., Wang, J. H., Pullen, N., & Springer, T. A. (2013). Domain 1 of mucosal addressin cell adhesion molecule has an I1-set fold and a flexible integrin-binding loop. Journal of Biological Chemistry, 288(9), 6284-6294.
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Normal Tissue
Figure 1 IHC staining of human appendix
Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/77998/169642_A_3_2_selected.jpg
Normal Tissue
Figure 2 Appendix
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_2_2_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes -
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_7_4.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HEK93, Hep G2, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000099866-MADCAM1
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Specifications
- Immunogen
- Human mucosal vascular addressin cell adhesion molecule 1
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MADCAM1
- Species Reactivity
- Human
- Clone
- 10G3
- Applications
- WB, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-509CL | Anti-Human MADCAM1 Recombinant Antibody (TAB-509CL) | IHC, FuncS | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-641 | Human Anti-MADCAM1 Recombinant Antibody (clone PF-547659) | WB, IF, FuncS | Human IgG |
| HPAB-0040-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0040-DJB) | ELISA | Human IgG2, κ |
| HPAB-0041-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0041-DJB) | ELISA | Human IgG4, κ |
| HPAB-0042-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0042-DJB) | ELISA | Human IgG4, κ |
| HPAB-0178-FY | Human Anti-MADCAM1 Recombinant Antibody (clone 7.16.6_S) | FC | Human IgG2, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-635 | Mouse Anti-MADCAM1 Recombinant Antibody (clone 10G3); Fab Fragment | WB, IF, FuncS | Mouse Fab |
| PFBL-636 | Human Anti-MADCAM1 Recombinant Antibody (clone PF-547659); Fab Fragment | WB, IF, FuncS | Human Fab |
| HPAB-0040-DJB-F(E) | Human Anti-MADCAM1 Recombinant Antibody; Fab Fragment (HPAB-0040-DJB-F(E)) | ELISA | Human Fab |
| HPAB-0041-DJB-F(E) | Human Anti-MADCAM1 Recombinant Antibody; Fab Fragment (HPAB-0041-DJB-F(E)) | ELISA | Human Fab |
| HPAB-0042-DJB-F(E) | Human Anti-MADCAM1 Recombinant Antibody; Fab Fragment (HPAB-0042-DJB-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-635 | Mouse Anti-MADCAM1 Recombinant Antibody (clone 10G3); scFv Fragment | WB, IF, FuncS | Mouse scFv |
| PSBL-636 | Human Anti-MADCAM1 Recombinant Antibody (clone PF-547659); scFv Fragment | WB, IF, FuncS | Human scFv |
| HPAB-0040-DJB-S(P) | Human Anti-MADCAM1 Recombinant Antibody; scFv Fragment (HPAB-0040-DJB-S(P)) | ELISA | Human scFv |
| HPAB-0178-FY-S(P) | Human Anti-MADCAM1 Recombinant Antibody (clone 7.16.6_S); scFv Fragment | FC | Human scFv |
| HPAB-692-FY-S(P) | Mouse Anti-MADCAM1 Recombinant Antibody; scFv Fragment (HPAB-692-FY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0714CL | Anti-Mouse Madcam1 Recombinant Antibody (MECA-367) | ELISA | |
| TAB-0714CL-S(P) | Anti-Mouse Madcam1 Recombinant Antibody scFv Fragment (MECA-367) | ELISA | |
| TAB-0714CL-F(E) | Anti-Mouse Madcam1 Recombinant Antibody Fab Fragment (MECA-367) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1715CQ | Recombinant Rat Anti-Madcam1 Antibody (11A55) | BL, WB | IgG2 |
| NEUT-1717CQ | Recombinant Mouse Anti-Madcam1 Antibody (CBL350) | BL, WB | IgG2a |
| NEUT-1718CQ | Recombinant Rat Anti-Madcam1 Antibody (MAB0842) | BL, FC, IHC-Fr, IP | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1716CQ | Recombinant Rat Anti-Madcam1 Antibody (CBL142) | Neut, WB | IgG2 |
| NEUT-1719CQ | Recombinant Rat Anti-Madcam1 Antibody (RM0284-11A55) | WB, Neut | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2118 | Hi-Affi™ Recombinant Rabbit Anti-MADCAM1 Monoclonal Antibody (DS2118AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-051CN | Human Anti-MADCAM1 Recombinant Antibody (NS-051CN) | ELISA, WB, IHC, FC, Block, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1284 | Anti-MAdCAM1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4162 | Anti-Human MADCAM1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY154 | Human Anti-MADCAM1 scFv-Fc Chimera (VS-0425-FY154) | IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC440 | Recombinant Anti-MADCAM1 Vesicular Antibody, EV Displayed (VS-0425-YC440) | Block, ELISA, FC, Cell-uptake |
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