Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-452MZ-F(E)) (CAT#: TAB-452MZ-F(E))
This product is a recombinant human antibody Fab fragment that recognizes Pro/latent-Myostatin. The antibody was purified by affinity chromatography. It can be used for Functional assays, Inhibition and other applications. Affinity optimization using antibody display was performed to identify a higher affinity variant Ab4. The affinity optimized variant Ab4 is similarly constructed on the human IgG4/lambda isotype frameworks. the Fab fragment of Ab4 binds to human pro- and latent- myostatin with a high affinity.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 IHC staining of human skeletal muscle
(Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg
(Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg
Figure 2 RNA cell line category: Group enriched (LHCN-M2, RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human Fab
- Specificity
- Human
- Species Reactivity
- Human
- Applications
- Enzyme-linked Immunosorbent Assay
- Related Disease
- Muscle atrophy
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MSTN; myostatin; GDF8; MSLHP; growth/differentiation factor 8; GDF-8; growth differentiation factor 8
- Gene ID
- 2660
- UniProt ID
- O14793
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
ScFv-Fc Chimeras
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0476CL | Mouse Anti-MSTN Recombinant Antibody (TAB-0476CL) | ELISA, WB | Mouse IgG |
| TAB-0477CL | Mouse Anti-MSTN Recombinant Antibody (TAB-0477CL) | ELISA, WB | Mouse IgG |
| TAB-0478CL | Mouse Anti-MSTN Recombinant Antibody (TAB-0478CL) | ELISA, WB | Mouse IgG |
| TAB-0479CL | Mouse Anti-MSTN Recombinant Antibody (TAB-0479CL) | ELISA, WB | Mouse IgG |
| TAB-0480CL | Mouse Anti-MSTN Recombinant Antibody (TAB-0480CL) | ELISA, WB | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
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