Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-452MZ-F(E))

Name: Human Anti-MSTN Recombinant Antibody; Fab Fragment (TAB-452MZ-F(E))
SKU: TAB-452MZ-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-452MZ-F(E)

This product is a recombinant human antibody Fab fragment that recognizes Pro/latent-Myostatin. The antibody was purified by affinity chromatography. It can be used for Functional assays, Inhibition and other applications. Affinity optimization using antibody display was performed to identify a higher affinity variant Ab4. The affinity optimized variant Ab4 is similarly constructed on the human IgG4/lambda isotype frameworks. the Fab fragment of Ab4 binds to human pro- and latent- myostatin with a high affinity.

Gene Expression

Normal Tissue Figure 1 IHC staining of human skeletal muscle

Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg

RNA Expression Figure 2 RNA cell line category: Group enriched (LHCN-M2, RH-30)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN

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Specifications

Host Species
Human

Derivation
Phage display library

Type
Human Fab

Specificity
Human

Species Reactivity
Human

Applications
Enzyme-linked Immunosorbent Assay

Related Disease
Muscle atrophy

Product Property

Purity
>95% as determined by SDS-PAGE

Buffer
PBS

Preservative
No preservatives

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
MSTN; myostatin; GDF8; MSLHP; growth/differentiation factor 8; GDF-8; growth differentiation factor 8

Gene ID
2660

UniProt ID
O14793

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-452MZ-F(E).pdf

MSDS

MSDS - TAB-452MZ-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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