Human Anti-MSTN Recombinant Antibody (TAB-453MZ) (CAT#: TAB-453MZ)
This product is a recombinant human antibody that recognizes Pro/latent-Myostatin. The antibody was purified by affinity chromatography. It can be used for Functional assays, Inhibition and other applications. Affinity optimization using antibody display was performed to identify a higher affinity variant Ab6. The affinity optimized variant Ab6 is similarly constructed on the human IgG4/lambda isotype frameworks. It binds to human pro- and latent- myostatin with a high affinity.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human skeletal muscle
(Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg
(Immunohistochemical staining of human skeletal muscle shows strong plasma positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9963/166785_B_1_6_selected.jpg
Figure 2 RNA cell line category: Group enriched (LHCN-M2, RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138379-MSTN
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG4, λ
- Specificity
- Human
- Species Reactivity
- Human
- Applications
- FuncS, Inhib
- Related Disease
- Muscle atrophy
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- MSTN; myostatin; GDF8; MSLHP; growth/differentiation factor 8; GDF-8; growth differentiation factor 8
- Gene ID
- 2660
- UniProt ID
- O14793
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2313z | Mouse Anti-MSTN Recombinant Antibody (clone 19F12) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2b |
| HPAB-0056-WJ | Human Anti-MSTN Recombinant Antibody (HPAB-0056-WJ) | ELISA, WB | Humanized IgG1, κ |
| VS3-XY1117 | Mouse Anti-MSTN Recombinant Antibody (clone 6E4B2) | ELISA, WB, IHC, FC | Mouse IgG2b |
| VS3-XY1118 | Mouse Anti-MSTN Recombinant Antibody (clone 6E4E6) | ELISA, WB, IHC | Mouse IgG2b |
| VS3-XY1119 | Mouse Anti-MSTN Recombinant Antibody (clone 6H12) | ELISA, WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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