Afuco™ Anti-Human NOTCH2 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-663CL
Anti-NOTCH2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is anti-Notch antibodies, and in particular, antibodies that bind Notch2 NRR and is used for B-cell neoplasms.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/714_F8_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Sertoli cells Staining: Low Intensity: Moderate Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48743/120061_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134250-NOTCH2
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Specifications
- Host Species
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- B-cell Neoplasms
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
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Related Diseases
Breast Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "NOTCH2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2555z | Mouse Anti-NOTCH2 Recombinant Antibody (clone 19B5) | ELISA, IHC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H67 | Anti-Human NOTCH2 Recombinant Antibody (TAB-H67) | FuncS, Block, ELISA | IgG2 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-552MZ | Human Anti-NOTCH2 Recombinant Antibody (TAB-552MZ) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-552MZ-S(P) | Human Anti-NOTCH2 Recombinant Antibody; scFv Fragment (TAB-552MZ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-552MZ-F(E) | Human Anti-NOTCH2 Recombinant Antibody; Fab Fragment (TAB-552MZ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0038-CN | Human Anti-NOTCH2 Recombinant Antibody (HPAB-0038-CN) | FC, ELISA | Human IgG2, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0039-CN | Human Anti-NOTCH2 Recombinant Antibody (HPAB-0039-CN) | FC, ELISA | Human IgG2, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0038-CN-S(P) | Human Anti-NOTCH2 Recombinant Antibody; scFv Fragment (HPAB-0038-CN-S(P)) | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0039-CN-S(P) | Human Anti-NOTCH2 Recombinant Antibody; scFv Fragment (HPAB-0039-CN-S(P)) | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0038-CN-F(E) | Human Anti-NOTCH2 Recombinant Antibody; Fab Fragment (HPAB-0038-CN-F(E)) | FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0039-CN-F(E) | Human Anti-NOTCH2 Recombinant Antibody; Fab Fragment (HPAB-0039-CN-F(E)) | FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H67 | Afuco™ Anti-NOTCH2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H67) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0595-WJ | Human Anti-NOTCH2 Recombinant Antibody (HPAB-0595-WJ) | ELISA, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0596-WJ | Human Anti-NOTCH2 Recombinant Antibody (HPAB-0596-WJ) | ELISA, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0595-WJ-F(E) | Human Anti-NOTCH2 Recombinant Antibody Fab Fragment (HPAB-0595-WJ-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0596-WJ-F(E) | Human Anti-NOTCH2 Recombinant Antibody Fab Fragment (HPAB-0596-WJ-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0597-WJ-F(E) | Human Anti-NOTCH2 Recombinant Antibody Fab Fragment (HPAB-0597-WJ-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0595-WJ-S(P) | Human Anti-NOTCH2 Recombinant Antibody scFv Fragment (HPAB-0595-WJ-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0596-WJ-S(P) | Human Anti-NOTCH2 Recombinant Antibody scFv Fragment (HPAB-0596-WJ-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0597-WJ-S(P) | Human Anti-NOTCH2 Recombinant Antibody scFv Fragment (HPAB-0597-WJ-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC621 | AbPlus™ Anti-NOTCH2 Magnetic Beads (VS-0724-YC621) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC80 | Rabbit Anti-NOTCH2 Antibody (VS-0924-YC80) - Cancer Stem Cell Marker | IHC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY171 | CytoStream™ Rat Anti-NOTCH2 Recombinant Antibody (clone 16F11) | FC | Rat IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY160 | Human Anti-NOTCH2 scFv-Fc Chimera (VS-0425-FY160) | ELISA, Block, WB | Human IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1507 | Anti-NOTCH2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC664 | Recombinant Anti-NOTCH2 Vesicular Antibody, EV Displayed (VS-0425-YC664) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4909 | Anti-Mouse NOTCH2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4908 | Anti-Human NOTCH2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC268 | SmartAb™ Recombinant Anti-NOTCH2 pH-dependent Antibody (VS-0825-YC268) | Block, ELISA | Human IgG2 kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1025-YC29 | Anti-NOTCH2 Antibody Prodrug, Protease Activated (VS-1025-YC29) | ISZ, Cyt, FuncS |
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