Anti-Human NOTCH3 Recombinant Antibody (TAB-559MZ) (CAT#: TAB-559MZ)
This antibody has similar activity in blocking Notch2 and Notch 3 signaling. This Notch-binding agent works as an antagonist and for treating diseases such as cancer.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FC
Figure 1 Anti-Human NOTCH3 Recombinant Antibody (TAB-559MZ) in FC
Flow cytometry analysis of U87 MG cells with purified antibody TAB-559MZ (QCAb253, Blue). Cells were blocked with Human TruStain FcXTM and washed with 0.5% BSA-PBS. Cells were then incubated with TAB-559MZ (5 μl/5x10^5 cells) for 60 min at 4°C. The secondary antibody was FITC anti-human IgG antibody (3 μl) for 60 min at 4°C.
SEC-HPLC
Figure 2 Anti-Human NOTCH3 Recombinant Antibody (TAB-559MZ) in SEC-HPLC
SEC-HPLC analysis of TAB-559MZ shows that the purity is more than 95%.
ELISA
Figure 3 Anti-Human NOTCH3 Recombinant Antibody (TAB-559MZ) in ELISA
ELISA analysis of TAB-559MZ was performed by coating with Recombinant Human NOTCH3 Protein.
The secondary antibody: HRP-anti-Human IgG
WB
Figure 4 Anti-Human NOTCH3 Recombinant Antibody (TAB-559MZ) in WB
Western blot analysis of TAB-559MZ was performed with Recombinant Human NOTCH3 Protein.
TAB-559MZ incubation concentration: 2 ng/μL.
The secondary antibody: Goat Anti-Human IgG(H+L)-HRP
Lane 1: Reducing antigen (0.1μg)
Lane 2: Reducing antigen (0.3μg)
Lane 3: Reducing antigen (0.6μg)
DB
Figure 5 Anti-Human NOTCH3 Recombinant Antibody (TAB-559MZ) in DB
Dot Blot analysis of TAB-559MZ was performed by coating with Recombinant Human NOTCH3 Protein.
The secondary antibody: HRP-anti-Human IgG
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human antibody
- Specificity
- Human
- Applications
- FC, Inhib, FuncS
- Related Disease
- Breast cancer, pancreatic cancer, melanoma, colon cancer
Applications
- Application Notes
- The antibody was validated for Flow Cytometry, Inhibition, Functional Assay. For details, refer to Published Data.
Target
- Alternative Names
- NOTCH3; notch 3; IMF2; CASIL; CADASIL; neurogenic locus notch homolog protein 3; Notch homolog 3
- Gene ID
- 4854
- UniProt ID
- Q9UM47
Related Resources
Breast Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NOTCH3"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1929z | Mouse Anti-NOTCH3 Recombinant Antibody (clone 22H2) | WB, ELISA | Mouse IgG2a |
| HPAB-1010WJ | Human Anti-NOTCH3 Recombinant Antibody (clone N3WCR3P1B12) | ELISA, WB, FC | Human IgG |
| HPAB-1011WJ | Human Anti-NOTCH3 Recombinant Antibody (clone hN3S2_160) | ELISA, WB, FC | Human IgG |
| HPAB-1012WJ | Human Anti-NOTCH3 Recombinant Antibody (clone N3LHCS_18) | ELISA, WB, FC | Human IgG |
| VS3-QX826 | Mouse Anti-NOTCH3 Recombinant Antibody (clone 487CT6.9.2) | WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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