Anti-Human NRG1 Antibody, Research Grade Biosimilar (CAT#: TAB-679CL)
Recombinant Human monoclonal antibody expressed in CHO binding to Human NRG1. The anti-neuregulin1 antibodiess which bind to both neuregulin1α and neuregulin 1β isoforms are used in treating diseases or disorders, such as cancer.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/1446_D11_3_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/1446_D11_3_selected.jpg
Figure 2 IHC staining of human caudate
(Immunohistochemical staining of human caudate shows weak positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_7_selected.jpg
(Immunohistochemical staining of human caudate shows weak positivity.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_7_selected.jpg
Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_7_5.jpg
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_7_5.jpg
Figure 4 Cerebellum
(Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_8.jpg
(Cells in granular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Purkinje cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_B_8_8.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_A_7_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10964/27907_A_7_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (A549, BJ, fHDF/TERT166, GAMG, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157168-NRG1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157168-NRG1
Specifications
- Host Species
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- NRG1; neuregulin 1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha
- Gene ID
- 3084
- UniProt ID
- A6MW56
Related Resources
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-579MZ | Mouse Anti-NRG1 Recombinant Antibody (TAB-579MZ) | ELISA, FC, WB | Mouse IgG |
| TAB-579MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-579MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-580MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-580MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-581MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-581MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-582MZ-S(P) | Mouse Anti-NRG1 Recombinant Antibody; scFv Fragment (TAB-582MZ-S(P)) | ELISA, FC | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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