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    Mouse Anti-TFRC Recombinant Antibody Fab Fragment (HPAB-0380-CN-F(E)) (CAT#: HPAB-0380-CN-F(E))

    This is a novel anti-CD71 monoclonal antibody, which is useful for inhibiting proliferation and killing malignant tumor cells, especially metastatic cutaneous and uveal melanoma cells.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to endosomes & lysosomes.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28598/546_F8_1_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/207_B2_1_blue_red_green.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/208_B2_1_blue_red_green.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_9_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Glandular cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_3.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining:

    Medium

    Intensity: Strong
    Quantity: <25%
    Pachytene spermatocytes
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_6_6.jpg
    Figure 7 Bone marrow
    Figure 7 Bone marrow
    (Hematopoietic cells
    Staining:

    High

    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_B_6_4.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Germinal center cells
    Staining:

    Medium

    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/
    membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/153/2800_A_8_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    (Cell lines ordered by descending RNA expression order.)
    * https://v21.proteinatlas.org/ENSG00000072274-TFRC
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    Figure 9 RNA cell line category: Cell line enhanced (HDLM-2)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000072274-TFRC

    Specifications

    • Immunogen
    • Human Thymic T cell clones
    • Host Species
    • Mouse
    • Type
    • Mouse Fab
    • Specificity
    • Human TFRC
    • Species Reactivity
    • Human
    • Applications
    • ELISA, FC, IF, IP
    • Related Disease
    • Metastatic cutaneous and uveal melanoma cells

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TFRC"

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    CAT Product Name Application Type
    AGTO-G067E Anti-TFRC immunotoxin HB21 (scFv)-PE Cytotoxicity assay, Function study
    AGTO-G067D Anti-TFRC immunotoxin HB21 (scFv)-DT Cytotoxicity assay, Function study
    AGTO-G067G Anti-TFRC immunotoxin HB21 (scFv)-Gel Cytotoxicity assay, Function study
    AGTO-G067R Anti-TFRC immunotoxin HB21 (scFv)-RTA Cytotoxicity assay, Function study
    AGTO-G067S Anti-TFRC immunotoxin HB21 (scFv)-Sap Cytotoxicity assay, Function study

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