Anti-Human TRAIL-R2 Recombinant Antibody (TAB-195)
CAT#: TAB-195
Recombinant monoclonal antibody to TRAIL-R2. It is an experimental agonistic human monoclonal antibody against TRAIL-R2 (DR5, APO-2) undergoing clinical trials for the treatment of cancer.








Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1 - lambda
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF, ICC
- MW
- 143.6 kDa
- Related Disease
- Cancers
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The TNFRSF10B antibody has been reported in applications of IP, WB.
Target
- Alternative Names
- Lexatumumab;845816-02-6;ETR2-ST01;HGS-ETR2;HGS1018;ETR2-ST01;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b;tumor necrosis factor receptor superfamily member 10B;CD262;DR5;KILLER;TRAIL R2;TRICK2A;TRICKB;Fas-like protein;death receptor 5;
- Gene ID
- 8795
- UniProt ID
- O14763
Customer Review
There are currently no Customer reviews or questions for TAB-195. Click the button above to contact us or submit your feedback about this product.

20.Aug,23

04.Nov,22

28.Jun,21
Q&As
-
Is the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab suitable for use in Western blotting?
A: Yes, the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) is suitable for use in Western blotting. It provides specific binding to TRAIL-R2, allowing for reliable detection in Western blot assays.
-
What are the storage recommendations for the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab?
A: The recommended storage condition for the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) is at -20°C or lower. For short-term storage, it can be kept at 2-8°C. To ensure stability, avoid repeated freeze-thaw cycles.
-
Can the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab be used in immunoprecipitation assays?
A: Yes, the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) can be used in immunoprecipitation assays. It provides specific binding to TRAIL-R2, enabling the successful precipitation of the target protein from complex mixtures.
-
Is the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab effective in ELISA applications?
A: Yes, the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) is effective in ELISA applications. It has been validated for use in such assays and provides reliable detection of TRAIL-R2.
-
What is the optimal dilution for using the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab in immunofluorescence?
A: The optimal dilution for using the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) in immunofluorescence is typically 1:100 to 1:500. It is advisable to perform a dilution series to determine the best working concentration for your specific experimental conditions.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-195, RRID: AB_3111865)
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Biosimilar Overview
Please refer to Lexatumumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lexatumumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "TNFRSF10B"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
NABL-052 | Recombinant Anti-human TNFRSF10B VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
HPAB-0703-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0703-YJ-VHH) | ELISA, Apop | Camelid VHH |
HPAB-0704-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0704-YJ-VHH) | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-203 | Human Anti-TNFRSF10B Recombinant Antibody (TAB-203) | ELISA, IP, FC, FuncS, Neut, IF, ICC | Human IgG1, κ |
TAB-253MZ | Anti-Human TNFRSF10B Recombinant Antibody (AU11) | ELISA, FuncS | Human antibody |
TAB-254MZ | Anti-Human TNFRSF10B Recombinant Antibody (AU12) | ELISA, FuncS | Human antibody |
TAB-253MZ-F(E) | Anti-Human TNFRSF10B Recombinant Antibody Fab Fragment (AU11) | FC, ELISA | Human antibody |
TAB-254MZ-F(E) | Anti-Human TNFRSF10B Recombinant Antibody Fab Fragment (AU12) | FC, ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-196 | Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 |
TAB-250MZ | Human Anti-TNFRSF10B Recombinant Antibody (TAB-250MZ) | FuncS | Humanized IgG |
TAB-251MZ | Human Anti-TNFRSF10B Recombinant Antibody (TAB-251MZ) | FuncS | Humanized IgG |
TAB-250MZ-F(E) | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (TAB-250MZ-F(E)) | FC, ELISA | Humanized Fab |
TAB-251MZ-F(E) | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (TAB-251MZ-F(E)) | FC, ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-625CL | Human Anti-TNFRSF10B Recombinant Antibody (TAB-625CL) | ELISA | Single Domain Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-029 | Human Anti-TNFRSF10B Recombinant Antibody (PABL-029) | WB, ELISA, FuncS | Human IgG |
PABL-030 | Human Anti-TNFRSF10B Recombinant Antibody (PABL-030) | WB, ELISA, FuncS | Human IgG |
MOB-2091MZ | Recombinant Mouse Anti-Human TNFRSF10B Antibody (clone C-L30) | FC | Mouse antibody |
HPAB-0412-CN | Human Anti-TNFRSF10B Recombinant Antibody (HPAB-0412-CN) | WB, ELISA | Human IgG1, λ |
FN-235CQ | Hamster Anti-Tnfrsf10b Recombinant Antibody (clone MD5-1) | FC, FuncS | Hamster IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-029 | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment | WB, ELISA, FuncS | Human Fab |
PFBL-030 | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (PFBL-030) | WB, ELISA, FuncS | Human Fab |
PFBC-123 | Human Anti-TNFRSF10B Recombinant Antibody (clone BDF1); Fab Fragment | ELISA | Human Fab |
HPAB-M0231-YC-F(E) | Human Anti-TNFRSF10B Recombinant Antibody (clone TR2-3); Fab Fragment | ELISA, WB | Human Fab |
HPAB-1145WJ-F(E) | Mouse Anti-TNFRSF10B Recombinant Antibody (clone E-11-13); Fab Fragment | ELISA, FC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-247MZ | Mouse Anti-TNFRSF10B Recombinant Antibody (TAB-247MZ) | ELISA, FC, FuncS, Inhib | Mouse IgG3, κ |
TAB-248MZ | Mouse Anti-TNFRSF10B Recombinant Antibody (TAB-248MZ) | ELISA, FuncS, Inhib | Mouse IgG |
TAB-249MZ | Mouse Anti-TNFRSF10B Recombinant Antibody (TAB-249MZ) | ELISA, FuncS, Inhib | Mouse IgG |
TAB-252MZ | Anti-Human TNFRSF10B Recombinant Antibody | ELISA | |
TAB-247MZ-F(E) | Mouse Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (TAB-247MZ-F(E)) | ELISA, WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3604 | Rabbit Anti-TNFRSF10B Recombinant Antibody (clone DS3604AB), PE | FC, WB | Rabbit IgG |
MOR-3605 | Rabbit Anti-Tnfrsf10b Recombinant Antibody (clone DS3605AB) | ELISA | Rabbit IgG |
MOR-4468 | Rabbit Anti-Tnfrsf10b Recombinant Antibody (clone SI562DS) | ELISA | Rabbit IgG |
MOR-4469 | Rabbit Anti-TNFRSF10B Recombinant Antibody (clone SI563DS) | ELISA, FC | Rabbit IgG |
MOR-4473 | Rabbit Anti-TNFRSF10B Recombinant Antibody (clone SI567DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-104LC | Human Anti-TNFRSF10B Recombinant Antibody (MOB-104LC) | FuncS | Chimeric (mouse/human) IgG1, κ |
VS-0724-XY43 | Mouse Anti-TNFRSF10B Agonistic Antibody (VS-0724-XY43) | Agonistic assays | Mouse IgG1 |
VS-0724-XY44 | Mouse Anti-TNFRSF10B Agonistic Antibody (clone B-D37) | ELISA, FC, FuncS, IP | Mouse IgG2b, kappa |
VS-0724-XY60 | Human Anti-TNFRSF10B Agonistic Antibody (clone AMG 655) | ELISA, Agonistic assays | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0303-YC-S(P) | Human Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (HPAB-0303-YC-S(P)) | ELISA, FuncS | Human scFv |
HPAB-0304-YC-S(P) | Human Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (HPAB-0304-YC-S(P)) | FuncS | Human scFv |
HPAB-1145WJ-S(P) | Mouse Anti-TNFRSF10B Recombinant Antibody (clone E-11-13); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1146WJ-S(P) | Mouse Anti-TNFRSF10B Recombinant Antibody (clone L-30-10); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1147WJ-S(P) | Mouse Anti-TNFRSF10B Recombinant Antibody (clone H-48-2); scFv Fragment | ELISA, FC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-196 | Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-196) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-203 | Afuco™ Anti-TNFRSF10B Recombinant Antibody (AFC-TAB-203), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | Human IgG1, κ |
AFC-TAB-180 | Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-180) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-195 | Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-195) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0125-FY72 | Human Anti-TNFRSF10B (clone Lexatumumab) scFv-Fc Chimera | ELISA, IP, FC, FuncS, Neut, IF, ADCC | Human IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC222 | Recombinant Anti-TNFRSF10B Vesicular Antibody, EV Displayed (VS-0425-YC222) | ELISA, FC, Neut, Cell-uptake |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY7361 | Anti-Mouse TNFRSF10B Immunohistochemistry Kit | IHC | |
VS-0525-XY7362 | Anti-Monkey TNFRSF10B Immunohistochemistry Kit | IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-YC232 | Recombinant Anti-TNFRSF10B (ECD x DD) Biparatopic Antibody, Tandem scFv | ELISA, FC, ICC, IF, IP, Neut | Tandem scFv |
Popular Products
Application: WB, IHC-Fr, IHC-P, ICC, IF
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
Application: WB, IHC-Fr, IHC-P, ICC, IF
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.