Anti-Human TRAIL-R2 Recombinant Antibody (TAB-195)

CAT#: TAB-195

Recombinant monoclonal antibody to TRAIL-R2. It is an experimental agonistic human monoclonal antibody against TRAIL-R2 (DR5, APO-2) undergoing clinical trials for the treatment of cancer.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Colon Figure 3 Liver Figure 4 Kidney Figure 5 Testis Figure 6 Lymph node Figure 7 RNA cell line category: Low cell line specificity Figure 7 RNA cell line category: Low cell line specificity

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1 - lambda
  • Specificity
  • Tested positive against native human antigen.
  • Species Reactivity
  • Human
  • MW
  • 143.6 kDa
  • Related Disease
  • Cancers

Product Property

  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The TNFRSF10B antibody has been reported in applications of IP, WB.

Target

  • Alternative Names
  • Lexatumumab;845816-02-6;ETR2-ST01;HGS-ETR2;HGS1018;ETR2-ST01;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b;tumor necrosis factor receptor superfamily member 10B;CD262;DR5;KILLER;TRAIL R2;TRICK2A;TRICKB;Fas-like protein;death receptor 5;
REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS
Inquiry
Navs

Customer Review

Submit a review or a question

There are currently no Customer reviews or questions for TAB-195. Click the button above to contact us or submit your feedback about this product.
Breast cancer biomarkers at key points during disease progression Michael White
20.Aug,23
Excellent for TRAIL-R2 Research
The Anti-Human TRAIL-R2 Therapeutic Antibody (Lexatumumab) has been excellent for our TRAIL-R2 studies. Its specificity and sensitivity are outstanding, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
Breast cancer biomarkers at key points during disease progression Laura Scott
04.Nov,22
Effective and Dependable
We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for TRAIL-R2 is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
Breast cancer biomarkers at key points during disease progression Brian Young
28.Jun,21
Consistent High-Quality Results
This antibody has proven to be consistent and dependable in our assays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for TRAIL-R2 have been particularly beneficial.

Q&As

  1. Is the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab suitable for use in Western blotting?

    A: Yes, the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) is suitable for use in Western blotting. It provides specific binding to TRAIL-R2, allowing for reliable detection in Western blot assays.

  2. What are the storage recommendations for the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab?

    A: The recommended storage condition for the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) is at -20°C or lower. For short-term storage, it can be kept at 2-8°C. To ensure stability, avoid repeated freeze-thaw cycles.

  3. Can the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab be used in immunoprecipitation assays?

    A: Yes, the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) can be used in immunoprecipitation assays. It provides specific binding to TRAIL-R2, enabling the successful precipitation of the target protein from complex mixtures.

  4. Is the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab effective in ELISA applications?

    A: Yes, the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) is effective in ELISA applications. It has been validated for use in such assays and provides reliable detection of TRAIL-R2.

  5. What is the optimal dilution for using the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab in immunofluorescence?

    A: The optimal dilution for using the anti-Human TRAIL-R2 therapeutic antibody Lexatumumab (TAB-195) in immunofluorescence is typically 1:100 to 1:500. It is advisable to perform a dilution series to determine the best working concentration for your specific experimental conditions.

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-195, RRID: AB_3111865)

Copy citation

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Article title:
DOI/PubMed URL:
Email:
Name:

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Biosimilar Overview

Please refer to Lexatumumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lexatumumab.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "TNFRSF10B"

Select a product category from the dropdown menu below to view related products.

CAT Product Name Application Type
TAB-625CL Human Anti-TNFRSF10B Recombinant Antibody (TAB-625CL) ELISA Single Domain Antibody
CAT Product Name Application Type
MOB-104LC Human Anti-TNFRSF10B Recombinant Antibody (MOB-104LC) FuncS Chimeric (mouse/human) IgG1, κ
VS-0724-XY43 Mouse Anti-TNFRSF10B Agonistic Antibody (VS-0724-XY43) Agonistic assays Mouse IgG1
VS-0724-XY44 Mouse Anti-TNFRSF10B Agonistic Antibody (clone B-D37) ELISA, FC, FuncS, IP Mouse IgG2b, kappa
VS-0724-XY60 Human Anti-TNFRSF10B Agonistic Antibody (clone AMG 655) ELISA, Agonistic assays Human IgG
CAT Product Name Application Type
AFC-TAB-196 Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-196) IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-203 Afuco™ Anti-TNFRSF10B Recombinant Antibody (AFC-TAB-203), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF Human IgG1, κ
AFC-TAB-180 Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-180) FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-195 Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-195) ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
CAT Product Name Application Type
VS-0125-FY72 Human Anti-TNFRSF10B (clone Lexatumumab) scFv-Fc Chimera ELISA, IP, FC, FuncS, Neut, IF, ADCC Human IgG1, scFv-Fc
CAT Product Name Application Type
VS-0425-YC222 Recombinant Anti-TNFRSF10B Vesicular Antibody, EV Displayed (VS-0425-YC222) ELISA, FC, Neut, Cell-uptake
CAT Product Name Application Type
VS-0525-YC232 Recombinant Anti-TNFRSF10B (ECD x DD) Biparatopic Antibody, Tandem scFv ELISA, FC, ICC, IF, IP, Neut Tandem scFv
Specific Inquiry
Go to compare Add to compare

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Go to compare

Go to compare