Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) (CAT#: TAB-196)
Recombinant monoclonal antibody to TRAIL-R2. It is a monoclonal antibody for the treatment of cancer.
Specific Inquiry
SDS-PAGE
Figure 1 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in SDS-PAGE
SDS-PAGE analysis of TAB-196 in reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result, different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
The purity of TAB-196 was greater than 95% as determined by SDS-PAGE.
SEC-HPLC
Figure 2 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in HPLC
The purity of TAB-196 was greater than 95% as determined by SEC-HPLC.
WB
Figure 3 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in WB
Western blot analysis of TAB-196 was performed by loading Recombinant Human TRAIL-R2.
TAB-196 incubation concentration: 2 ng/μL.
The secondary antibody: HRP-anti-human IgG
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)
ELISA
Figure 4 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in ELISA
ELISA analysis of TAB-196 was performed by coating with Recombinant Human TRAIL-R2.
The secondary antibody: HRP-anti-human IgG
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC, ICC
- MW
- 144.6 kDa
- Related Disease
- Unknown
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The TNFRSF10B antibody has been reported in applications of WB, Inhib, FC, IHC.
Target
- Alternative Names
- Tigatuzumab;918127-53-4;CS-1008;TRA-8;CS-1008;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b;tumor necrosis factor receptor superfamily member 10B;CD262;DR5;KILLER;TRAIL R2;TRICK2A;TRICKB;Fas-like protein;death receptor 5;cytotoxic TRAIL
- Gene ID
- 8795
- UniProt ID
- O14763
Related Resources
Please refer to Tigatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tigatuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-052 | Recombinant Anti-human TNFRSF10B VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| HPAB-0703-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0703-YJ-VHH) | ELISA, Apop | Camelid VHH |
| HPAB-0704-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0704-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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