Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) (CAT#: TAB-196)
Recombinant monoclonal antibody to TRAIL-R2. It is a monoclonal antibody for the treatment of cancer.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in SDS-PAGE
SDS-PAGE analysis of TAB-196 in reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result, different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
The purity of TAB-196 was greater than 95% as determined by SDS-PAGE.
SEC-HPLC
Figure 2 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in HPLC
The purity of TAB-196 was greater than 95% as determined by SEC-HPLC.
WB
Figure 3 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in WB
Western blot analysis of TAB-196 was performed by loading Recombinant Human TRAIL-R2.
TAB-196 incubation concentration: 2 ng/μL.
The secondary antibody: HRP-anti-human IgG
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)
ELISA
Figure 4 Anti-Human TRAIL-R2 Recombinant Antibody (TAB-196) in ELISA
ELISA analysis of TAB-196 was performed by coating with Recombinant Human TRAIL-R2.
The secondary antibody: HRP-anti-human IgG
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC, ICC
- MW
- 144.6 kDa
- Related Disease
- Unknown
Product Property
- Purity
- >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The TNFRSF10B antibody has been reported in applications of WB, Inhib, FC, IHC.
Target
- Alternative Names
- Tigatuzumab;918127-53-4;CS-1008;TRA-8;CS-1008;TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b;tumor necrosis factor receptor superfamily member 10B;CD262;DR5;KILLER;TRAIL R2;TRICK2A;TRICKB;Fas-like protein;death receptor 5;cytotoxic TRAIL
- Gene ID
- 8795
- UniProt ID
- O14763
Related Resources
Please refer to Tigatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tigatuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-052 | Recombinant Anti-human TNFRSF10B VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| HPAB-0703-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0703-YJ-VHH) | ELISA, Apop | Camelid VHH |
| HPAB-0704-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0704-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
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