Recombinant Anti-human VCAM-1 Intrabody [(D-Arg)9] (CAT#: IAB-B067(A))
Recombinant anti-VCAM-1 intrabody linked to (D-Arg)9 works within cells to bind human VCAM-1, expressed in CHO cells.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69867/1706_F12_18_cr57d839e75f94b_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69867/1706_F12_18_cr57d839e75f94b_selected.jpg
Figure 2 Kidney
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_8_5.jpg
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_8_5.jpg
Figure 3 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_6_6.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_8_8.jpg
Figure 5 High expression in spleen
(Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_B_7_4.jpg
(Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_B_7_4.jpg
Figure 6 RNA cell line category: Group enriched (HHSteC, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162692-VCAM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162692-VCAM1
Specifications
- Immunogen
- human vascular cell adhesion molecule 1
- Host Species
- mouse
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Products can be used for: Fluorescence-activated cell sorting; Enzyme-linked Immunosorbent Assay; Immunofluorescence; Functional studies
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- Store at – 20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.
Target
- Alternative Names
- VCAM1; vascular cell adhesion molecule 1; CD106; INCAM-100; vascular cell adhesion protein 1; CD106 antigen
- Gene ID
- 7412
- UniProt ID
- P19320
Related Resources
TNF Signaling Pathway
AGE-RAGE Signaling Pathway in Diabetic Complications
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "VCAM1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1467z | Mouse Anti-VCAM1 Recombinant Antibody (clone 23B9) | ELISA, FC, IHC, FuncS | Mouse IgG1 |
| MOB-2174MZ | Recombinant Mouse Anti-Human VCAM1 Antibody (clone TUB) | ELISA, FC, IHC-Fr, IP | Mouse antibody |
| MRO-2266-CN | Rabbit Anti-VCAM1 Polyclonal Antibody (MRO-2266-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-CJ745 | Rabbit Anti-VCAM1 Recombinant Antibody (VS3-CJ745) | WB, ICC, IF, IHC, IP | Rabbit IgG |
| VS3-XY1584 | Mouse Anti-VCAM1 Recombinant Antibody, FITC (clone 4AP8B1) | FC, IF | Mouse IgG2b |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-061 | Recombinant Anti-Human VCAM1 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
| HPAB-0351-YC-VHH | Recombinant Dromedary Anti-VCAM1 Single Domain Antibody (cAbVCAM1-8) | ELISA, FC | Dromedary VHH |
| HPAB-0352-YC-VHH | Recombinant Dromedary Anti-VCAM1 Single Domain Antibody (cAbVCAM1-9) | ELISA, FC | Dromedary VHH |
| HPAB-0353-YC-VHH | Recombinant Dromedary Anti-VCAM1 Single Domain Antibody (cAbVCAM1-5) | FuncS | Dromedary VHH |
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B067(G) | Recombinant Anti-human VCAM-1 Intrabody [+36 GFP] | FACS, ICC, FuncS | scFv-(+36GFP) |
| IAB-B067(T) | Recombinant Anti-human VCAM-1 Intrabody [Tat] | PCA, WB, FuncS | scFv-Tat |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-249CQ | Anti-Human VCAM1 Recombinant Antibody (H6) | ELISA | Human antibody |
| TAB-249CQ-S(P) | Anti-Human VCAM1 Recombinant Antibody scFv Fragment (H6) | ELISA, FC, Neut | Human antibody |
| TAB-249CQ-F(E) | Anti-Human VCAM1 Recombinant Antibody Fab Fragment (H6) | ELISA, FC, Neut | Human antibody |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-250CQ | Human Anti-VCAM1 Recombinant Antibody (TAB-250CQ) | ELISA, FC, WB, IHC | Humanized IgG |
| TAB-251CQ | Human Anti-VCAM1 Recombinant Antibody (TAB-251CQ) | ELISA, FC, WB, IHC | Humanized IgG |
| TAB-250CQ-S(P) | Human Anti-VCAM1 Recombinant Antibody; scFv Fragment (TAB-250CQ-S(P)) | ELISA, FC, WB, IHC | Humanized scFv |
| TAB-250CQ-F(E) | Human Anti-VCAM1 Recombinant Antibody; Fab Fragment (TAB-250CQ-F(E)) | ELISA, FC, WB, IHC | Humanized Fab |
| TAB-251CQ-F(E) | Human Anti-VCAM1 Recombinant Antibody; Fab Fragment (TAB-251CQ-F(E)) | ELISA, FC, WB, IHC | Humanized Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2248CQ | Rat Anti-Vcam1 Recombinant Antibody (VMC209) | FC, IP, Block, IHC | Rat IgG2a, κ |
| NEUT-2249CQ | Rat Anti-Vcam1 Recombinant Antibody (clone M/K-2.7) | Block, IF | Rat IgG1 |
| NEUT-2251CQ | Mouse Anti-VCAM1 Recombinant Antibody (clone B-K9) | Block, FuncS, FC | Mouse IgG1 |
| NEUT-2252CQ | Mouse Anti-VCAM1 Recombinant Antibody (clone M/K-2), PE | FC, ICC, IF, Block, IP | Mouse IgG1, κ |
| NEUT-2254CQ | Mouse Anti-VCAM1 Recombinant Antibody (clone BBIG-V1) | Block, WB, IP, ICC | Mouse IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2250CQ | Rat Anti-Vcam1 Recombinant Antibody (clone mAb0829) | Neut, FC, IHC, IHC-Fr, IP, CyTOF | Rat IgG1 |
| NEUT-2253CQ | Mouse Anti-VCAM1 Recombinant Antibody (clone 1.G11B1) | WB, Neut, ELISA, FC, IHC, IHC-Fr, IP, ICC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3829 | Rabbit Anti-VCAM1 Recombinant Antibody (clone DS3829AB) | WB, ICC, IP | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0218-YC-S(P) | Human Anti-VCAM1 Recombinant Antibody (clone HS-1); scFv Fragment | ELISA, Neut | Rabbit scFv |
| HPAB-0860-CN-S(P) | Human Anti-VCAM1 Recombinant Antibody (clone 7H); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-AP205-YC-S(P) | Human Anti-VCAM1 Recombinant Antibody; scFv Fragment (HPAB-AP205-YC-S(P)) | IHC, DB | Human scFv |
| HPAB-AP206-YC-S(P) | Human Anti-VCAM1 Recombinant Antibody; scFv Fragment (HPAB-AP206-YC-S(P)) | IHC, DB | Human scFv |
| HPAB-AP207-YC-S(P) | Human Anti-VCAM1 Recombinant Antibody; scFv Fragment (HPAB-AP207-YC-S(P)) | IHC, DB | Human scFv |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-100CN | Human Anti-VCAM1 Recombinant Antibody (clone 7C) | ELISA | Human IgG |
| NS-101CN | Human Anti-VCAM1 Recombinant Antibody (clone 4B) | ELISA | Human IgG |
| NS-100CN-F(E) | Human Anti-VCAM1 Recombinant Antibody (clone 7C); Fab Fragment | ELISA | Human Fab |
| NS-101CN-F(E) | Human Anti-VCAM1 Recombinant Antibody (clone 4B); Fab Fragment | ELISA | Human Fab |
| NS-100CN-S(P) | Human Anti-VCAM1 Recombinant Antibody (clone 7C); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0860-CN-F(E) | Human Anti-VCAM1 Recombinant Antibody (clone 7H); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-AP205-YC-F(E) | Human Anti-VCAM1 Recombinant Antibody; Fab Fragment (HPAB-AP205-YC-F(E)) | IHC, DB | Human Fab |
| HPAB-AP206-YC-F(E) | Human Anti-VCAM1 Recombinant Antibody; Fab Fragment (HPAB-AP206-YC-F(E)) | IHC, DB | Human Fab |
| HPAB-AP207-YC-F(E) | Human Anti-VCAM1 Recombinant Antibody; Fab Fragment (HPAB-AP207-YC-F(E)) | IHC, DB | Human Fab |
| FAMAB-0009JF-F(E) | Human Anti-VCAM1 Recombinant Antibody (clone ch2A2); Fab Fragment | FC, ELISA, FuncS | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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