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Kunitz domains anti-FN1 (SKD-L093)

The Kunitz domain that bound fibronectin (α5β1) was isolated from the library using phage display techonology. Kunitz domains are stable as standalone peptides, able to recognise specific protein structures, and also work as competitive protease inhibitors in their free form. After affinity maturation, Kunitz domains variants were identified having affinities for fibronectin (α5β1) as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.      
Datasheet
Specifications
Scaffold Name
Kunitz domains
Origin
Knottin protein
Variable Regions
9-13 amino acids
Target
Fibronectin (α5β1)
Species Reactivity
Human
Expression Host
E. coli
Applications
ELISA; IHC; Microscopy; FC; WB; FuncS
Target
Alternative Names
knottin protein; Kunitz domains; FN; CIG; FNZ; MSF; ED-B; FINC
Entrez Gene ID
2335
UniProt ID
B7ZLE5

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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