Anti-Human CSF1 Recombinant Antibody (Lacnotuzumab) (CAT#: TAB-029ML)
Recombinant monoclonal antibody to CSF1. Lacnotuzumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, breast, Pigmented villonodular synovitis (PVNS), Tenosynovitis.
Specific Inquiry
PK
Figure 1 Mean (standard error) collagen type 1 cross-linked C-telopeptide: ratio to baseline versus time profiles by lacnotuzumab dose.
CTX-I, collagen type 1 cross-linked C-telopeptide; LZB, lacnotuzumab; q21d, every 21 days.
Pognan, F., Couttet, P., Demin, I., Jaitner, B., Pang, Y., Roubenoff, R.,... & Woerly, G. (2019). CSF-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes. The Journal of pharmacology and experimental therapeutics.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- IgG1, κ
- Specificity
- Human CSF1
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS, PK
- Conjugate
- Unconjugated
- CAS
- 1831128-32-5
- Generic Name
- Lacnotuzumab
- UNII
- 77624NN1TU
- Related Disease
- Cancers, breast, Pigmented villonodular synovitis (PVNS), Tenosynovitis
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The CSF1 antibody has been reported in applications of ELISA, IHC, FC, IP, IF, FuncS, PK.
Target
- Alternative Names
- Colony stimulating factor 1; "colony stimulating factor 1 macrophage"; M-CSF; macrophage colony stimulating factor 1; MCSF; MGC31930
- Gene ID
- 1435
- UniProt ID
- P09603
Related Resources
Please refer to Lacnotuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lacnotuzumab.
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Lacnotuzumab"
Afuco™ Anti-CSF1 ADCC Recombinant Antibody (Lacnotuzumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CSF1. Lacnotuzumab is a human monoclonal antibody that can be potentially used in the treatment of Cancers, breast, Pigmented villonodular synovitis (PVNS), Tenosynovitis.
See other products for "CSF1"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-245-F(E) | Recombinant Anti-human CSF1 Antibody Fab Fragment | WB, RIA, FuncS | Fab |
| HPAB-0532-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0532-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0533-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0533-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0534-CN-F(E) | Mouse Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0534-CN-F(E)) | ELISA, FC, Neut | Mouse Fab |
| HPAB-0535-CN-F(E) | Human Anti-CSF1 Recombinant Antibody; Fab Fragment (HPAB-0535-CN-F(E)) | ELISA, FC, Neut | Humanized Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-187CL | Human Anti-CSF1 Recombinant Antibody (TAB-187CL) | ELISA | Human IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1152CT | Recombinant Mouse anti-Human CSF1 Monoclonal antibody | ELISA, WB | |
| HPAB-0532-CN | Mouse Anti-CSF1 Recombinant Antibody (HPAB-0532-CN) | ELISA, FC, Neut | Mouse IgG |
| HPAB-0533-CN | Mouse Anti-CSF1 Recombinant Antibody (HPAB-0533-CN) | ELISA, FC, Neut | Mouse IgG |
| HPAB-0534-CN | Mouse Anti-CSF1 Recombinant Antibody (HPAB-0534-CN) | ELISA, FC, Neut | Mouse IgG |
| VS3-CJ542 | Rabbit Anti-CSF1 Recombinant Antibody (VS3-CJ542) | WB, ICC, IHC, IP | Rabbit IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-501CQ | Mouse Anti-CSF1 Recombinant Antibody (clone 3V17) | Neut, WB | Mouse IgG2 |
| NEUT-502CQ | Mouse Anti-CSF1 Recombinant Antibody (clone CBL140) | Neut, WB | Mouse IgG2 |
| NEUT-503CQ | Mouse Anti-CSF1 Recombinant Antibody (clone CBL441) | WB, Neut | Mouse IgG2a |
| NEUT-505CQ | Rat Anti-Csf1 Recombinant Antibody (clone CBL205) | WB, Neut | Rat IgG2 |
| NEUT-506CQ | Rat Anti-Csf1 Recombinant Antibody (clone CBL535) | WB, Neut | Rat IgG2b |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-504CQ | Rat Anti-Csf1 Recombinant Antibody (clone 5A1) | Block | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0824 | Hi-Affi™ Rabbit Anti-CSF1 Recombinant Antibody (clone DS824AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0150CQ-S(P) | Human Anti-CSF1 Recombinant Antibody; scFv Fragment (HPAB-0150CQ-S(P)) | ELISA, WB, FC, Inhib | Human scFv |
| HPAB-0151CQ-S(P) | Human Anti-CSF1 Recombinant Antibody; scFv Fragment (HPAB-0151CQ-S(P)) | ELISA, WB, FC, Inhib | Human scFv |
| HPAB-0110-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody; scFv Fragment (HPAB-0110-WJ-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-0748-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody (clone 88); scFv Fragment | ELISA, WB, FC | Human scFv |
| HPAB-0749-WJ-S(P) | Human Anti-CSF1 Recombinant Antibody (clone 100); scFv Fragment | ELISA, WB, FC | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-029ML | Afuco™ Anti-CSF1 ADCC Recombinant Antibody (Lacnotuzumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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