PE-A*02:02/Human TP53 (CQLAKTCPV) MHC Tetramer (CAT#: MHC-LC3066)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TP53 of peptide CQLAKTCPV covering 135-143 and A*02:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:02
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • TP53
  • Antigen Species
  • Human
  • Peptide
  • CQLAKTCPV
  • Range
  • 135-143
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
  • Alternative Names
  • TP53; P53_HUMAN Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13); P53; BCC7; LFS1; TRP53

Related Resources

  • Related Diseases

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "TP53"

Select a product category from the dropdown menu below to view related products.
Please select product type
Single-domain Antibody MHC Tetramer for Cancer Rabbit Monoclonal Antibody Model Organism Antibody Recombinant Antibody scFv Fragment Antibody Fab Fragment Antibody Epitope-Specific Antibody

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for MHC-LC3066. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare