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PE-A*02:02/Human TP53 (CQLAKTCPV) MHC Tetramer (CAT#: MHC-LC3066)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human TP53 of peptide CQLAKTCPV covering 135-143 and A*02:02 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39239/651_G2_2_selected.jpg
Figure 2 IF staining of human cell line A549
Figure 2 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63532/1113_C11_2_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, cytosol & mitochondria.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79965/1999_E7_4_selected.jpg
Figure 4 IF staining of human cell line U-251 MG
Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39238/656_H2_1_red_green.jpg
Normal Tissue
Figure 5 Oral mucosa
Figure 5 Oral mucosa
(Squamous epithelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2973/6986_A_8_1.jpg
Figure 6 Colon
Figure 6 Colon
(Enterocytes
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2973/6986_A_9_3.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000141510-TP53
Figure 7 RNA cell line category: Low cell line specificity
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141510-TP53

Specifications

  • Allele
  • A*02:02
  • Class
  • Class I
  • Antigen
  • TP53
  • Antigen Species
  • Human
  • Peptide
  • CQLAKTCPV
  • Range
  • 135-143
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
  • Alternative Names
  • TP53; P53_HUMAN Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13); P53; BCC7; LFS1; TRP53

Related Resources

  • Related Diseases

Downloads

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Single-domain Antibody

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MHC Tetramer for Cancer

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MHC-LC052 APC-A*02:01/Human p53 (KLCPVQLWV) MHC Tetramer FCM

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3644 Rabbit Anti-TP53 Recombinant Antibody (clone DS3644AB) IHC-P Rabbit IgG
MOR-4524 Rabbit Anti-TP53 Recombinant Antibody (clone TH32DS) WB, IF, ICC Rabbit IgG
MOR-4698 Rabbit Anti-TP53 Recombinant Antibody (clone TH212DS) WB, IF, ICC, FC, ChIP, FRET Rabbit IgG

Model Organism Antibody

CAT Product Name Application Type
MD-ZBF-YC001 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-1.1) WB, ICC Mouse antibody
MD-ZBF-YC002 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-2.1) WB, ICC, IHC Mouse antibody
MD-ZBF-YC003 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-3.1) WB, ICC Mouse antibody
MD-ZBF-YC004 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-4.1) WB, ICC Mouse antibody
MD-ZBF-YC005 Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-5.1) WB, ICC, IHC Mouse antibody

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0001-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); Fab Fragment IHC, WB, ELISA Mouse Fab
HPAB-0002-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 240); Fab Fragment IP, ELISA Mouse Fab
HPAB-0003-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 246); Fab Fragment IP, ELISA Mouse Fab
HPAB-0004-YC-F(E) Mouse Anti-TP53 Recombinant Antibody (clone 421); Fab Fragment IP, ELISA Mouse Fab
HPAB-1568WJ-F(E) Mouse Anti-TP53 Recombinant Antibody; Fab Fragment (clone 11D3) ELISA, WB Mouse Fab

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0633CQ Mouse Anti-TP53 Recombinant Antibody (clone p53-11) WB Mouse IgG

Recombinant Antibody

CAT Product Name Application Type
MRO-1045-CN Rabbit Anti-TP53 Recombinant Antibody (clone JB42-26) WB, IHC, FC, IP, IF Rabbit IgG
MRO-2103-CN Rabbit Anti-TP53 Polyclonal Antibody (MRO-2103-CN) WB, IF, IHC, FC Rabbit IgG
HPAB-0662-YJ Mouse Anti-TP53 Recombinant Antibody (clone Ab421) ELISA Mouse IgG
ZG-1013F Mouse Anti-TP53 Recombinant Antibody (clone Bp53.12) FC, ICC, IHC-Fr, IHC-P, WB Mouse IgG2a
ZG-1023F Mouse Anti-TP53 Recombinant Antibody (clone DO-1) ELISA, FC, IB, ICC, IF, IHC-Fr, IHC-P, WB Mouse IgG2a, κ

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