Mouse Anti-TP53 Recombinant Antibody (clone 421); scFv Fragment (CAT#: HPAB-0004-YC-S(P))
The p53 protein is the product of a tumor suppressor gene that functions to arrest the growth of mutated or aberrant cells. The p53 protein is a transcription factor that binds specifically to a consensus site present in the regulatory sequences of p53-dependent genes. Thus the wild-type p53 molecule, and not only the mutated p53 molecule, can serve as a target for a potentially therapeutic anti-tumor immune response.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39239/651_G2_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39239/651_G2_2_selected.jpg
Figure 2 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63532/1113_C11_2_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63532/1113_C11_2_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, cytosol & mitochondria.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79965/1999_E7_4_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm, cytosol & mitochondria.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79965/1999_E7_4_selected.jpg
Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39238/656_H2_1_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39238/656_H2_1_red_green.jpg
Figure 5 Oral mucosa
(Squamous epithelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2973/6986_A_8_1.jpg
(Squamous epithelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2973/6986_A_8_1.jpg
Figure 6 Colon
(Enterocytes
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2973/6986_A_9_3.jpg
(Enterocytes
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2973/6986_A_9_3.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000141510-TP53
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000141510-TP53
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141510-TP53
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141510-TP53
Specifications
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human TP53
- Species Reactivity
- Human, Mouse
- Clone
- 421
- Applications
- IP, ELISA
- Related Disease
- Lung carcinoma metastasis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 421"
See other products for "TP53"
Select a product category from the dropdown menu below to view related products.
Please select product type
ScFv Antibody Products
Single Domain Antibody Products
MHC Tetramer Products for Cancer
Rabbit Monoclonal Antibody Products
Model Organism Antibody Products
Fab Antibody Products
Epitope-Specific Antibody Products
IgG Antibody Products
Antibody Magnetic Beads
Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-994 | Recombinant anti-TP53 antibody svFv Fragment | ELISA, Agonist | scFv |
| HPAB-0001-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); scFv Fragment | IHC, WB, ELISA | Mouse scFv |
| HPAB-0002-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 240); scFv Fragment | IP, ELISA | Mouse scFv |
| HPAB-0003-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 246); scFv Fragment | IP, ELISA | Mouse scFv |
| HPAB-0005-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone ME1); scFv Fragment | ELISA | Mouse scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0004-YC-S(P). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: ELISA, WB, BLI, SPR
Application: WB, ELISA, FuncS
Application: FC, IHC-Fr, IP, ELISA, Block
Application: ELISA, IHC, FC, IP, IF, FuncS
-2.png)
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
