+ Filter

TP53

Anti-TP53 Products

Recombinant Mouse anti-Human TP53 Monoclonal antibody (5E2) (MOB-1423CT)
- Species Reactivity: Human
- Application: ELISA, FC, ICC, IF, IHC-Fr, IHC-P, IP, WB
Compare

PE-A*02:01/Human p53 (YLGSYGFRL) MHC Tetramer (MHC-LC075)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: YLGSYGFRL
- Conjugate: PE
Compare

APC-A*02:01/Human p53 (YLGSYGFRL) MHC Tetramer (MHC-LC076)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: YLGSYGFRL
- Conjugate: APC
Compare

BV421-A*02:01/Human p53 (YLGSYGFRL) MHC Tetramer (MHC-LC077)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: YLGSYGFRL
- Conjugate: BV421
Compare

PE-A*02:01/Human p53 (GLAPPQHLIRV) MHC Tetramer (MHC-LC036)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: GLAPPQHLIRV
- Conjugate: PE
Compare

APC-A*02:01/Human p53 (GLAPPQHLIRV) MHC Tetramer (MHC-LC037)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: GLAPPQHLIRV
- Conjugate: APC
Compare

BV421-A*02:01/Human p53 (GLAPPQHLIRV) MHC Tetramer (MHC-LC038)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: GLAPPQHLIRV
- Conjugate: BV421
Compare

PE-A*02:01/Human p53 (LLGRNSFEV) MHC Tetramer (MHC-LC139)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: LLGRNSFEV
- Conjugate: PE
Compare

PE-A*02:01/Human p53 (KLCPVQLWV) MHC Tetramer (MHC-LC051)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: KLCPVQLWV
- Conjugate: PE
Compare

APC-A*02:01/Human p53 (KLCPVQLWV) MHC Tetramer (MHC-LC052)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: KLCPVQLWV
- Conjugate: APC
Compare

PE-A*02:02/Human TP53 (LLGRNSFEV) MHC Tetramer (MHC-LC2142)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LLGRNSFEV
- Conjugate: PE
Compare

PE-A*02:05/Human TP53 (LLGRNSFEV) MHC Tetramer (MHC-LC2143)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LLGRNSFEV
- Conjugate: PE
Compare

PE-A*24:02/Human TP53 (KYPENFFLL) MHC Tetramer (MHC-LC2368)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: KYPENFFLL
- Conjugate: PE
Compare

PE-A*02:01/Human TP53 (RMPEAAPPV) MHC Tetramer (MHC-LC2718)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: RMPEAAPPV
- Conjugate: PE
Compare

PE-A*02:01/Human TP53 (AAPPVAPA) MHC Tetramer (MHC-LC3045)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: AAPPVAPA
- Conjugate: PE
Compare

PE-A*02:02/Human TP53 (AAPPVAPA) MHC Tetramer (MHC-LC3046)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: AAPPVAPA
- Conjugate: PE
Compare

PE-A*02:03/Human TP53 (AAPPVAPA) MHC Tetramer (MHC-LC3047)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: AAPPVAPA
- Conjugate: PE
Compare

PE-A*02:06/Human TP53 (AAPPVAPA) MHC Tetramer (MHC-LC3048)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: AAPPVAPA
- Conjugate: PE
Compare

PE-A*68:02/Human TP53 (AAPPVAPA) MHC Tetramer (MHC-LC3049)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: AAPPVAPA
- Conjugate: PE
Compare

PE-A*02:01/Human TP53 (ALNKMFCQL) MHC Tetramer (MHC-LC3052)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: ALNKMFCQL
- Conjugate: PE
Compare

PE-A*02:02/Human TP53 (ALNKMFCQL) MHC Tetramer (MHC-LC3053)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: ALNKMFCQL
- Conjugate: PE
Compare

PE-A*02:03/Human TP53 (ALNKMFCQL) MHC Tetramer (MHC-LC3054)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: ALNKMFCQL
- Conjugate: PE
Compare

PE-A*02:06/Human TP53 (ALNKMFCQL) MHC Tetramer (MHC-LC3055)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: ALNKMFCQL
- Conjugate: PE
Compare

PE-A*02:01/Human TP53 (CQLAKTCPV) MHC Tetramer (MHC-LC3065)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: CQLAKTCPV
- Conjugate: PE
Compare

PE-A*02:02/Human TP53 (CQLAKTCPV) MHC Tetramer (MHC-LC3066)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: CQLAKTCPV
- Conjugate: PE
Compare

PE-A*02:03/Human TP53 (CQLAKTCPV) MHC Tetramer (MHC-LC3067)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: CQLAKTCPV
- Conjugate: PE
Compare

PE-A*02:06/Human TP53 (CQLAKTCPV) MHC Tetramer (MHC-LC3068)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: CQLAKTCPV
- Conjugate: PE
Compare

PE-A*02:01/Human TP53 (ITLEDSSGNLL) MHC Tetramer (MHC-LC3092)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: ITLEDSSGNLL
- Conjugate: PE
Compare

PE-A*02:02/Human TP53 (LAPPQHLIRV) MHC Tetramer (MHC-LC3122)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LAPPQHLIRV
- Conjugate: PE
Compare

PE-A*02:03/Human TP53 (LAPPQHLIRV) MHC Tetramer (MHC-LC3123)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LAPPQHLIRV
- Conjugate: PE
Compare

PE-A*02:06/Human TP53 (LAPPQHLIRV) MHC Tetramer (MHC-LC3124)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LAPPQHLIRV
- Conjugate: PE
Compare

PE-Mamu-A1*001:01/Human TP53 (RMPEAAPPV) MHC Tetramer (MHC-LC4506)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: RMPEAAPPV
- Conjugate: PE
Compare

PE-Mamu-A1*001:01/Human TP53 (KTYQGSYGFRL) MHC Tetramer (MHC-LC4516)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: KTYQGSYGFRL
- Conjugate: PE
Compare

PE-Mamu-A1*001:01/Human TP53 (STSRHKKLM) MHC Tetramer (MHC-LC4533)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: STSRHKKLM
- Conjugate: PE
Compare

BV421-A*02:01/Human p53 (KLCPVQLWV) MHC Tetramer (MHC-LC053)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: KLCPVQLWV
- Conjugate: BV421
Compare

PE-A*02:01/Human p53 (RMPEAAPPV) MHC Tetramer (MHC-LC063)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: RMPEAAPPV
- Conjugate: PE
Compare

APC-A*02:01/Human p53 (RMPEAAPPV) MHC Tetramer (MHC-LC064)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: RMPEAAPPV
- Conjugate: APC
Compare

BV421-A*02:01/Human p53 (RMPEAAPPV) MHC Tetramer (MHC-LC065)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: RMPEAAPPV
- Conjugate: BV421
Compare

PE-A*02:01/Human p53 (SLPPPGTRV) MHC Tetramer (MHC-LC069)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: SLPPPGTRV
- Conjugate: PE
Compare

APC-A*02:01/Human p53 (SLPPPGTRV) MHC Tetramer (MHC-LC070)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: SLPPPGTRV
- Conjugate: APC
Compare

BV421-A*02:01/Human p53 (SLPPPGTRV) MHC Tetramer (MHC-LC071)
- Class: Class I
- Antigen: p53
- Antigen Species: Human
- Peptide: SLPPPGTRV
- Conjugate: BV421
Compare

PE-A*02:02/Human TP53 (ITLEDSSGNLL) MHC Tetramer (MHC-LC3093)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: ITLEDSSGNLL
- Conjugate: PE
Compare

PE-A*02:01/Human TP53 (LLPENNVLSPL) MHC Tetramer (MHC-LC3125)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LLPENNVLSPL
- Conjugate: PE
Compare

PE-A*02:02/Human TP53 (LLPENNVLSPL) MHC Tetramer (MHC-LC3126)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LLPENNVLSPL
- Conjugate: PE
Compare

PE-A*02:03/Human TP53 (LLPENNVLSPL) MHC Tetramer (MHC-LC3127)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LLPENNVLSPL
- Conjugate: PE
Compare

PE-A*02:06/Human TP53 (LLPENNVLSPL) MHC Tetramer (MHC-LC3128)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LLPENNVLSPL
- Conjugate: PE
Compare

PE-A*68:02/Human TP53 (LLPENNVLSPL) MHC Tetramer (MHC-LC3129)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: LLPENNVLSPL
- Conjugate: PE
Compare

PE-A*02:01/Human TP53 (STPPPGTRV) MHC Tetramer (MHC-LC3155)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: STPPPGTRV
- Conjugate: PE
Compare

PE-A*02:02/Human TP53 (STPPPGTRV) MHC Tetramer (MHC-LC3156)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: STPPPGTRV
- Conjugate: PE
Compare

PE-A*02:03/Human TP53 (STPPPGTRV) MHC Tetramer (MHC-LC3157)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: STPPPGTRV
- Conjugate: PE
Compare

PE-A*68:02/Human TP53 (STPPPGTRV) MHC Tetramer (MHC-LC3158)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: STPPPGTRV
- Conjugate: PE
Compare

PE-B*27:05/Human TP53 (GRNSFEVRV) MHC Tetramer (MHC-LC4459)
- Class: Class I
- Antigen: TP53
- Antigen Species: Human
- Peptide: GRNSFEVRV
- Conjugate: PE
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 70237-85) (HPAB-0001-YC)
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: IHC, WB, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 240) (HPAB-0002-YC)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 246) (HPAB-0003-YC)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 421) (HPAB-0004-YC)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 6B2) (MRO-1147-CN)
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 6B5) (MRO-1148-CN)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
Compare

Mouse Anti-TP53 Recombinant Antibody (clone C8-A11) (MRO-1149-CN)
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: WB, IF, IHC
Compare

Rabbit Anti-TP53 Recombinant Antibody (clone CBACN-418) (MRO-1150-CN)
- Species Reactivity: Human, Zebrafish
- Type: Rabbit IgG
- Application: WB, IF
Compare

Rabbit Anti-TP53 Recombinant Antibody (clone CBACN-640) (MRO-2351-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
Compare

Rabbit Anti-TP53 Recombinant Antibody (clone CBACN-641) (MRO-2352-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
Compare

Mouse Anti-TP53 Recombinant Antibody (clone Ab421) (HPAB-0662-YJ)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (MOB-0157F) (MOB-0157F)
- Species Reactivity: Human, Rat, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
Compare

Mouse Anti-TP53 Recombinant Antibody (MOB-0159F) (MOB-0159F)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC-P, IF, WB
Compare

Rabbit Anti-TP53 Recombinant Antibody (clone S11-K) (ZG-0332U)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: ELISA, WB, IP, ICC
Compare

Rabbit Anti-TP53 Recombinant Antibody (clone M26-A) (ZG-0345U)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
Compare

Rabbit Anti-Phospho-TP53 (T55) Recombinant Antibody (clone 3C3) (ZG-0599U)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IF
Compare

Rabbit Anti-Phospho-TP53 (S392) Recombinant Antibody (clone 3F5) (ZG-0600U)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB
Compare

Recombinant anti-TP53 antibody svFv Fragment (DrMAB-994)
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, Agonist
Compare

Recombinant Anti-p53 VHH Single Domain Antibody (PNBL-072) (PNBL-072)
- Derivation: Llama
- Species Reactivity: Human
- Type: Llama VHH
- Application: Inhib, IP, WB, ELISA, FuncS
Compare

Mouse Anti-TP53 Recombinant Antibody (clone Ab421); Fab Fragment (HPAB-0662-YJ-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone Ab421); scFv Fragment (HPAB-0662-YJ-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare

Camelid Anti-TP53 Recombinant Single Domain Antibody (HPAB-0746-YJ-VHH) (HPAB-0746-YJ-VHH)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Camelid VHH
- Application: ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody; Fab Fragment (clone 11D3) (HPAB-1568WJ-F(E))
- Derivation: Hybridoma
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 421); Fab Fragment (HPAB-0004-YC-F(E))
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone ME1); Fab Fragment (HPAB-0005-YC-F(E))
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
Compare

Human Anti-TP53 Recombinant Antibody Fab Fragment (HPAB-0006-YC-F(E)) (HPAB-0006-YC-F(E))
- Derivation: Human synthetic combinatorial library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, FuncS
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); scFv Fragment (HPAB-0001-YC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: IHC, WB, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 240); scFv Fragment (HPAB-0002-YC-S(P))
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 246); scFv Fragment (HPAB-0003-YC-S(P))
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 421); scFv Fragment (HPAB-0004-YC-S(P))
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone ME1); scFv Fragment (HPAB-0005-YC-S(P))
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
Compare

Human Anti-TP53 Recombinant Antibody scFv Fragment (HPAB-0006-YC-S(P)) (HPAB-0006-YC-S(P))
- Derivation: Human synthetic combinatorial library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC, FuncS
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); Fab Fragment (HPAB-0001-YC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: IHC, WB, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 240); Fab Fragment (HPAB-0002-YC-F(E))
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone 246); Fab Fragment (HPAB-0003-YC-F(E))
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: IP, ELISA
Compare

Mouse Anti-TP53 Recombinant Antibody (clone p53-11) (EPAF-0633CQ)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-1.1) (MD-ZBF-YC001)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish, Human
- Type: Mouse antibody
- Application: WB, ICC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-2.1) (MD-ZBF-YC002)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish
- Type: Mouse antibody
- Application: WB, ICC, IHC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-3.1) (MD-ZBF-YC003)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish
- Type: Mouse antibody
- Application: WB, ICC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-4.1) (MD-ZBF-YC004)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish, Human
- Type: Mouse antibody
- Application: WB, ICC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-5.1) (MD-ZBF-YC005)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish
- Type: Mouse antibody
- Application: WB, ICC, IHC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-6.1) (MD-ZBF-YC006)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish
- Type: Mouse antibody
- Application: WB, ICC, IHC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-7.1) (MD-ZBF-YC007)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish
- Type: Mouse antibody
- Application: WB, ICC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-8.1) (MD-ZBF-YC008)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish
- Type: Mouse antibody
- Application: WB, ICC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-9.1) (MD-ZBF-YC009)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish
- Type: Mouse antibody
- Application: WB, ICC, IHC
Compare

Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-10.1) (MD-ZBF-YC010)
- Derivation: Hybridoma
- Species Reactivity: Zebrafish, Human
- Type: Mouse antibody
- Application: WB
Compare

Rabbit Anti-TP53 Recombinant Antibody (clone DS3644AB) (MOR-3644)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
Compare

Rabbit Anti-TP53 Recombinant Antibody (clone TH212DS) (MOR-4698)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, ICC, FC, ChIP, FRET
Compare

View More Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.

Background

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants.

Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance