PE-DR1/Human CEACAM5 (QRLLLTASLLTFWNP) MHC Tetramer (CAT#: MHC-LC1992)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human CEACAM5 of peptide QRLLLTASLLTFWNP covering 16-30 and DR1 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19758/1660_G5_2_selected.jpg

(Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in a subset of leukocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11041/ihc_selected.jpg

(Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Gradient
Gradient: Ascending
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21/19_A_7_3.jpg

(Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21/19_A_6_3.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105388-CEACAM5

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000105388-CEACAM5
Specifications
- Allele
- DR1
- Class
- Class II
- MHC Species
- Human
- Antigen
- CEACAM5
- Antigen Species
- Human
- Peptide
- QRLLLTASLLTFWNP
- Range
- 16-30
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
- Alternative Names
- CEACAM5; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e
- Gene ID
- 1048
- UniProt ID
- P06731
Downloads
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See other products for "CEACAM5"
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CAT | Product Name | Application | Type |
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MOB-1138z | Mouse Anti-CEACAM5 Recombinant Antibody (clone 32B10) | WB, IP, IF, FC | Mouse IgG1, κ |
MOB-0089MZ | Recombinant Mouse Anti-Carcinoembryonic antigen Antibody (clone A9203) | ELISA | Mouse antibody |
MRO-1770-CN | Rabbit Anti-CEACAM5 Polyclonal Antibody (MRO-1770-CN) | WB, IF, IHC, FC | Rabbit IgG |
VS-0323-XY5 | Human Anti-CEACAM5 Recombinant Antibody (clone αCEA4-8A) | ELISA | Human IgG |
VS3-WK1656 | Recombinant Mouse Anti-CEACAM5 Capture Antibody (clone 15A12) | ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
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