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Recombinant Anti-FAP Antibody (Fc glycosylation/Non fucosylated) (Gly-153LC)

This product is a non-glycosylated human monoclonal antibody with glycosylation site in the Fc region. The antibody 4G8 with enhanced ADCC specifically binds human FAP and can be potentially used in the treatment of breast cancer, colon adenocarcinomas and NSCLC.      

Glyco-engineering
Classification
Fc glycosylation/Non fucosylated
Glycosylation site
Fc region
Glycosylation Type
N-glycosylation
Activity
Enhanced ADCC
Specifications
Target
FAP (Fibroblast Activation Protein)
Host Animal
Human
Type
Human antibody
Specificity
Human
Antibody Isotype
IgG1
Clone
4G8
Expression Host
HEK293-EBNA
Applications
ELISA
Target
Alternative Names
FAP; fibroblast activation protein, alpha; FAPA; SIMP; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha
Related Disease
Breast cancer, colon adenocarcinomas and NSCLC
Entrez Gene ID
2191
UniProt ID
B4DLR2

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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