AbPlus™ Anti-FAP Magnetic Beads (ESC14)
CAT#: VS-0424-XY97
The AbPlus Anti-FAP Magnetic Beads (ESC14) is an innovative affinity resin which is bound with anti-FAP specific antibody (ESC14). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of FAP protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_9_3.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_8_4.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_4_6.jpg
Normal Tissue
Figure 5 Smooth muscle
Smooth muscle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_B_6_7.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+, hTERT-RPE1, U-138 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000078098-FAP
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-FAP specific antibody (ESC14)
- Target
- FAP
- Immunogen
- Recombinant human FAP
- Target Species
- Human, Mouse
- Antibody Clone
- ESC14
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- FAP; fibroblast activation protein, alpha; FAPA; SIMP; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase
- Gene ID
- 2191
- UniProt ID
- B4DLR2
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Fap"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-211 | Anti-Human FAP Recombinant Antibody (TAB-211) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022WM | Human Anti-FAP Recombinant Antibody (TAB-022WM) | FC, ELISA | Human IgG1 |
| TAB-024WM | Human Anti-FAP Recombinant Antibody (TAB-024WM) | IHC, ELISA, FC, IF | Human IgG1 |
| TAB-022WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-022WM-S(P)) | FC, ELISA | Human scFv |
| TAB-022WM-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-022WM-F(E)) | FC, ELISA | Human Fab |
| TAB-024WM-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-024WM-F(E)) | ELISA, FC, IF | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-150LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-151LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-152LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-153LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-153LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0172-CN | Human Anti-FAP Recombinant Antibody (HPAB-0172-CN) | ELISA, IHC | Chimeric (mouse/human) IgG1, κ |
| HPAB-0176-CN | Human Anti-FAP Recombinant Antibody (clone cF19) | ELISA, FC, IHC, IP, IF | Chimeric (mouse/human) IgG1 |
| HPAB-0668-YJ | Human Anti-FAP Recombinant Antibody (HPAB-0668-YJ) | ELISA, Inhib, IHC, IF, FuncS | Human IgG1 |
| HPAB-A1373-YJ | Human Anti-FAP Recombinant Antibody (clone 34) | ELISA, IHC, FC, Inhib | Human IgG1 |
| HPAB-A1374-YJ | Human Anti-FAP Recombinant Antibody (clone 18) | ELISA, FC, Inhib | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0170-CN-S(P)) | ELISA, IF | Human scFv |
| HPAB-0171-CN-S(P) | Mouse Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0171-CN-S(P)) | ELISA | Mouse scFv |
| HPAB-0173-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0173-CN-S(P)) | ELISA | Humanized scFv |
| HPAB-0175-CN-S(P) | Human Anti-FAP Recombinant Antibody (clone ESC14); scFv Fragment | ELISA, WB, FC, IHC, IP | Human scFv |
| HPAB-0668-YJ-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0668-YJ-S(P)) | ELISA, Inhib, IHC, IF, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0170-CN-F(E)) | ELISA, IF | Human Fab |
| HPAB-0171-CN-F(E) | Mouse Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0171-CN-F(E)) | ELISA | Mouse Fab |
| HPAB-0173-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0173-CN-F(E)) | ELISA | Humanized Fab |
| HPAB-0175-CN-F(E) | Human Anti-FAP Recombinant Antibody (clone ESC14); Fab Fragment | ELISA, WB, FC, IHC, IP | Human Fab |
| HPAB-0172-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0172-CN-F(E)) | ELISA, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0619-CN | Recombinant Dromedary Anti-FAP Single Domain Antibody (HPAB-0619-CN) | ELISA | VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-211 | Afuco™ Anti-FAP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-211) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0661 | PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
| MHC-CN0662 | APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
| MHC-YF431 | A*02:01/Human FAP (GLFKCGIAV) MHC Pentamer | FCM | |
| MHC-YF432 | A*02:01/Human FAP alpha (ALVCYGPGI) MHC Pentamer | FCM | |
| MHC-YF573 | H-2Kb/Human muFAP alpha (SDYYFSWL) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY118 | Human Anti-FAP (clone cF19) scFv-Fc Chimera | FC, IHC, IP | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY813 | Anti-FAP Immunohistochemistry Kit | IHC | |
| VS-0525-XY2444 | Anti-Human FAP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC379 | CytoStream™ Mouse Anti-FAP Recombinant Antibody (VS13-YC379) | IHC-P, FC, ELISA | Mouse IgG1 |
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