Fap
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2a
- Application: ELISA
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, WB, FC, IHC, IP
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human IgG1
- Application: IHC, ELISA, FC, IF
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, WB
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC, IHC, IP, IF
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, Inhib, IHC, IF, FuncS
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human Fab
- Application: ELISA, FC, IF
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA
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- Class: Class I
- Antigen: muFAP alpha
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA, IF
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, FC, IHC, IP, IF
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG1, κ
- Application: ELISA
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IP, FC, FuncS, Neut, IF
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human scFv
- Application: ELISA, FC, IF
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF, IP
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC, ELISA
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unconjugated
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: FITC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: PE
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unconjugated
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: FITC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: PE
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, FC
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human IgG1
- Application: SPR, IHC
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- Class: Class I
- Antigen: FAP alpha
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, Inhib
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, IHC, FC, Inhib
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unconjugated
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: FITC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: PE
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- Target: FAP
- Target Species: Human, Mouse
- Application: IP, Protein Purification
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, Inhib, IHC, IF, FuncS
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL13
- Host: Human
- Cytokine 1 Species: Mouse
- Molecule Class: IgG-IL13
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL13
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG-IL13
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: scfv-IL12
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Human
- Cytokine 1 Species: Mouse
- Molecule Class: scfv-IL12
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human scFv
- Application: FC, ELISA, IF
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human Fab
- Application: FC, ELISA, IF
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA, IF
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA, IF
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, Inhib, IHC, IF, FuncS
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- Derivation: VHH phage display library
- Species Reactivity: Human
- Type: VHH
- Application: ELISA
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, IHC
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, WB, FC, IHC, IP
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, IP, IF
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: ELISA
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, IF
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, WB, FC, IHC, IP
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized scFv
- Application: ELISA
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, IF
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- Target: fibroblast activation proteinα
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
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- Target: FAP
- Linker: MC-PABC (maleimidocaproyl-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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For Research Use Only. Not For Clinical Use.