Fap
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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- Class: Class I
- Antigen: muFAP alpha
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: FAP alpha
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: Unconjugated
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: FITC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: ALVCYGPGI
- Conjugate: PE
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: Unconjugated
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: FITC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: GLFKCGIAV
- Conjugate: PE
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: Unconjugated
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: FITC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: APC
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- Class: Class I
- Antigen: FAP
- Antigen Species: Human
- Peptide: SDYYFSWL
- Conjugate: PE
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IF, IP
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, Inhib
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, IHC, FC, Inhib
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA, IF
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, FC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IP, FC, FuncS, Neut, IF
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA, IF
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human scFv
- Application: FC, ELISA, IF
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human Fab
- Application: FC, ELISA, IF
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, Inhib, IHC, IF, FuncS
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, Inhib, IHC, IF, FuncS
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, Inhib, IHC, IF, FuncS
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- Species Reactivity: Human, Mouse, Cynomolgus monkey
- Type: Human IgG1
- Application: SPR, IHC
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, WB, FC, IHC, IP
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized scFv
- Application: ELISA
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- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA
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- Derivation: VHH phage display library
- Species Reactivity: Human
- Type: VHH
- Application: ELISA
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, WB, FC, IHC, IP
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG1, κ
- Application: ELISA
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human Fab
- Application: ELISA, FC, IF
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, ELISA
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human scFv
- Application: ELISA, FC, IF
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, ELISA
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
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- Target: FAP
- Linker: MC-PABC (maleimidocaproyl-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
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- Target: FAP
- Linker: AO-Mc-
- Drug: MMAE (Monomethyl auristatin E)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: ELISA, IP, FC, FuncS, Neut, IF, WB
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: ELISA
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- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, IF
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, FC, IHC, IP, IF
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, IHC
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, WB, FC, IHC, IP
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, FC, IHC, IP, IF
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2a
- Application: ELISA
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA, IF
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: Fc region
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, IP, IF
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: Fab-IL10
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- Target: FAP
- Species Reactivity: Human
- Cytokine 1: IL10
- Host: Human
- Cytokine 1 Species: Human
- Molecule Class: IgG1-IL10
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, IF
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- Species Reactivity: Human, Mouse, Monkey
- Type: Human IgG1
- Application: IHC, ELISA, FC, IF
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC, ELISA
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- Target: fibroblast activation proteinα
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, IHC
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For Research Use Only. Not For Clinical Use.