AbPlus™ Anti-BRD4 Magnetic Beads (D392) (CAT#: VS-0424-XY33)

• Applications
• Immunoprecipitation-Mass Spectrometry

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-BRD4 specific antibody (D392)

• Target
• BRD4

• Immunogen
• Recombinant BRD4 protein

• Target Species
• Human

• Antibody Clone
• D392

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is homologous to the mouse protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

• Alternative Names
• BRD4; bromodomain containing 4; CAP; MCAP; HUNK1; HUNKI; bromodomain-containing protein 4; bromodomain-containing 4; chromosome-associated protein

• Gene ID
• 23476

• UniProt ID
• O60885

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