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BRD4
Loading...Anti-BRD4 Products
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, IF, FC, IP, ChIP
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- AbPlus™ Anti-BRD4 Magnetic Beads (D392) (VS-0424-XY33)
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- Target: BRD4
- Target Species: Human
- Application: IP-MS, Protein Purification
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- Anti-Mouse BRD4 Immunohistochemistry Kit (VS-0525-XY829)
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- Species Reactivity: Human, Mouse
- Target: BRD4
- Application: IHC
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- Anti-BRD4 Immunohistochemistry Kit (VS-0325-XY261)
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- Species Reactivity: Human, Mouse, Rat
- Target: BRD4
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is homologous to the mouse protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.