Rabbit Anti-CD46 Recombinant Antibody (VS-0723-WK258) (CAT#: VS-0723-WK258)
This product is a rabbit IgG antibody that recognizes human CD46, which has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. This antibody is recommended for flow cytometry (1/100) and ELISA (1/5000-1/10000) assays.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/if_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/ihc_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/211_E5_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/211_E5_1_blue_red_green.jpg
Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/209_E5_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10401/209_E5_1_blue_red_green.jpg
Figure 5 Colon
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16903/38899_A_9_3.jpg
(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16903/38899_A_9_3.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117335-CD46
Specifications
- Immunogen
- Recombinant human CD46 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CD46
- Species Reactivity
- Human
- Applications
- ELISA, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 1×PBS
- Preservative
- No Preservative
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- ELISA: 1/5000-1/10000
Flow Cytometry: 1/100
Target
- Alternative Names
- CD46; AHUS2; MCP; MIC10; TLX; TRA2.10
- Gene ID
- 4179
- UniProt ID
- P15529
- Long Name
- CD46 Molecule
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1132z | Mouse Anti-CD46 Recombinant Antibody (clone 12A2) | WB, ELISA, FC, IF, IHC, IP, FuncS | Mouse IgG1, κ |
| HPAB-0524-CN | Human Anti-CD46 Recombinant Antibody (HPAB-0524-CN) | WB, ELISA, FC, IHC, IP | Human IgG1 |
| HPAB-0525-CN | Human Anti-CD46 Recombinant Antibody (HPAB-0525-CN) | WB, ELISA, FC, IHC, IP | Human IgG1 |
| HPAB-0367-YC | Mouse Anti-CD46 Recombinant Antibody (clone SC1.N122) | ELISA, FC | Mouse IgG |
| HPAB-0368-YC | Mouse Anti-CD46 Recombinant Antibody (HPAB-0368-YC) | ELISA, FC | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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