Human Anti-DDR1 Recombinant Antibody (clone PRTH-101)
CAT#: VS-0126-FY41
The DDR1 antibody (VS-0126-FY41) is a specialized Human monoclonal antibody optimized for the precise detection and study of DDR1. Developed against purified antigens, this antibody exhibits exceptional binding affinity and high specificity for its target. It is validated for use in ELISA, making it a versatile tool for various experimental protocols. Specifically recognizing the AA 192-367 region, it ensures accurate results across different research contexts. With demonstrated reactivity in Human and Mouse models, it is suitable for multiple biological research applications. This high-quality reagent is essential for investigating the functional roles of DDR1 in cellular signaling and its involvement in various human disease mechanisms.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57194/if_selected.jpg
Normal Tissue
Figure 2 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_9_8.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_5.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_8_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_A_5_6.jpg
Normal Tissue
Figure 6 Skin
Melanocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25656/57796_B_7_1.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HaCaT, HBEC3-KT, RT4, T-47d)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204580-DDR1
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Specifications
- Host Species
- Human
- Derivation
- Derived from Rabbit
- Type
- Human IgG1
- Antibody Isotype
- IgG1
- Species Reactivity
- Human, Mouse
- Clone
- PRTH-101
- Applications
- ELISA
- Related Disease
- Lung Adenocarcinoma, Pancreatic Cancer, Kidney Fibrosis, Atherosclerosis, Chronic Obstructive Pulmonary Disease (COPD)
Product Property
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Discoidin Domain Receptor Tyrosine Kinase 1; CD167 Antigen-Like Family Member A; Protein-Tyrosine Kinase RTK-6; Mammary Carcinoma Kinase 10; Tyrosine-Protein Kinase CAK; Cell Adhesion Kinase; Tyrosine Kinase DDR; EC 2.7.10.1; EDDR1; NTRK4; PTK3A; HGK2; RTK6; TRKE; CAK; NEP; Epithelial Discoidin Domain-Containing Receptor 1
- Gene ID
- 780
- UniProt ID
- Q08345
- Long Name
- Discoidin Domain Receptor Tyrosine Kinase 1
- Function
- A receptor tyrosine kinase that is uniquely activated by collagen rather than soluble growth factors. It regulates cell adhesion, proliferation, and extracellular matrix remodeling, playing a key role in wound healing and cancer progression.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "DDR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-436 | Mouse Anti-DDR1 Recombinant Antibody (clone mAb 3E3) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-433 | Mouse Anti-DDR1 Recombinant Antibody (clone 3E3); Fab Fragment | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-433 | Mouse Anti-DDR1 Recombinant Antibody (clone mAb 3E3); scFv Fragment | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-176MZ | Anti-Human DDR1 Recombinant Antibody (DDR1-ab1) | FuncS | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-177MZ | Anti-Human DDR1 Recombinant Antibody (DDR1-ab2) | FuncS | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-178MZ | Anti-Human DDR1 Recombinant Antibody (DDR1-ab3) | FuncS | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-179MZ | Anti-Human DDR1 Recombinant Antibody (AB2004) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-180MZ | Anti-Human DDR1 Recombinant Antibody (AB2009) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-181MZ | Anti-Human DDR1 Recombinant Antibody (AB2041) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-182MZ | Mouse Anti-DDR1 Recombinant Antibody (TAB-182MZ) | FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-183MZ | Anti-Human DDR1 Recombinant Antibody (1F10) | WB, ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-176MZ-S(P) | Anti-Human DDR1 Recombinant Antibody scFv Fragment (DDR1-ab1) | IF | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-177MZ-S(P) | Anti-Human DDR1 Recombinant Antibody scFv Fragment (DDR1-ab2) | IF | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1224CT | Recombinant Mouse anti-Human DDR1 Monoclonal antibody (3H5F23) | ELISA, IHC-P, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0953 | Hi-Affi™ Rabbit Anti-DDR1 Recombinant Antibody (clone DS953AB) | ELISA, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0077-CN | Human Anti-DDR1 Recombinant Antibody (clone APE05570) | ELISA, FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0078-CN | Human Anti-DDR1 Recombinant Antibody (clone APE05571) | ELISA, FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0077-CN-S(P) | Human Anti-DDR1 Recombinant Antibody (clone APE05570); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0078-CN-S(P) | Human Anti-DDR1 Recombinant Antibody (clone APE05571); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0077-CN-F(E) | Human Anti-DDR1 Recombinant Antibody (clone APE05570); Fab Fragment | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0078-CN-F(E) | Human Anti-DDR1 Recombinant Antibody (clone APE05571); Fab Fragment | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0061-LSX | Mouse Anti-DDR1 Recombinant Antibody (clone AB2026) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0061-LSX-S(P) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2026); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0062-LSX-S(P) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2039); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0061-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2026); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0062-LSX-F(E) | Mouse Anti-DDR1 Recombinant Antibody (clone AB2039); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1235 | AbPlus™ Anti-DDR1 Magnetic Beads (VS-0724-YC1235) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY638 | Anti-DDR1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC431 | Recombinant Anti-DDR1 Vesicular Antibody, EV Displayed (VS-0425-YC431) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC97 | SmartAb™ Recombinant Anti-DDR1 pH-dependent Antibody (Clone AB2004) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
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