Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0442-FY-S(P)) (CAT#: HPAB-0442-FY-S(P))
This product is a recombinant human antibody scFv fragment that recognizes FGFR4. The antibody was purified by affinity chromatography.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg
Figure 2 IHC staining of human gall bladder
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg
Figure 3 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg
Figure 8 RNA cell line category: Group enriched (CACO-2, Hep G2, RH-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human FGFR4
- Species Reactivity
- Human
- Applications
- Inhib
- Related Disease
- Heart hypertrophy or chronic kidney disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Fibroblast Growth Factor Receptor 4; EC 2.7.10.1; JTK2; TKF; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; Hydroxyaryl-Protein Kinase; Protein-Tyrosine Kinase;
- Gene ID
- 2264
- UniProt ID
- P22455
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3383z | Mouse Anti-FGFR4 Recombinant Antibody (clone 31F7) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
| HPAB-2922LY | Mouse Anti-FGFR4 Recombinant Antibody (HPAB-2922LY) | ELISA, FC | Mouse IgG |
| VS1-YJ59 | Mouse Anti-FGFR4 Recombinant Antibody (clone 19H3) | WB, IP | Mouse IgG1 |
| VS3-XY708 | Mouse Anti-FGFR4 Recombinant Antibody (clone 4H2B10B2) | ELISA, WB, IHC | Mouse IgG1 |
| VS-0723-WK114 | Human Anti-FGFR4 Recombinant Antibody (VS-0723-WK114) | FC | Chimeric (rabbit/human) IgG1 |
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