Human Anti-FLT1 Recombinant Antibody (clone 6F9) (CAT#: HPAB-1702-FY)
This product is a recombinant antibody that recognizes FLT1. The monoclonal antibody 6F9 reacts with the epitope of FLT1.
Specific Inquiry
ELISA
Figure 1 A chart depicts the results of an ELISA-based binding assay measuring in vitro binding activity of embodiments of anti-VEGFR-I antibodies to VEGFR-I.
Block
Figure 2 A chart depicts the results of an ELISA-based blocking assay measuring in vitro competition of embodiments of anti-VEGFR-I antibodies with P1GF for VEGFR-I binding.
Block
Figure 3 A chart depicts the results of an ELISA-based blocking assay measuring in vitro competition of embodiments of anti-VEGFR-I antibodies with VEGF for VEGFR-I binding.
FC
Figure 4 Shows the results of flow cytometry analysis showing binding reactivity of embodiments of anti-VEGFR-I antibodies with VEGFR-I expressing porcine aorta endothelial cells.
Inhib
Figure 5 Shows a dose response curve showing the inhibition of VEGF stimulated cell proliferation in DU4475 breast carcinoma cells treated with embodiments of anti-VEGFR-I antibodies in a dose response manner.
Inhib
Figure 6 Shows a chart plotting tumor growth of DU4475 (FIG. 25A) and MDA-MB-435 (FIG. 25B) breast tumors versus days after treatment with anti-VEGFR-I antibodies 18F1, 6F9 and 15F11.
Specifications
- Immunogen
- Recombinant human VEGFR-I
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human FLT1
- Species Reactivity
- Human
- Clone
- 6F9
- Applications
- ELISA, WB
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The FLT1 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Blocking, Flow Cytometry, Inhibition.
Target
- Alternative Names
- Fms Related Tyrosine Kinase 1; Vascular Permeability Factor Receptor; Fms-Related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Vascular Permeability Factor Receptor); Vascular Endothelial Growth Factor Receptor 1; Tyrosine-Protein Kinase Receptor FLT; Tyrosine-Protein Kinase FRT; Fms-Like Tyrosine Kinase 1; EC 2.7.10
- Gene ID
- 2321
- UniProt ID
- P17948
Related Resources
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-177 | Anti-Human VEGFR-1 Recombinant Antibody (TAB-177) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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