Recombinant Anti-IL13 Biparatopic Antibody, Tandem scFv (Anrukinzumab x Clone IMA-026) (CAT#: VS-0525-YC216)

This biparatopic antibody (bpAb) binds two distinct IL13 epitopes, having been designed as a tandem scFv. The Anrukinzumab scFv (specific for the IL-13 epitope that binds IL-4Rα) is N-terminally fused to the IMA-026 scFv (specific for the IL-13 epitope that binds IL-13Rα1 and IL-13Rα2).

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
RNA Expression

Specifications

  • Host Animal 1
  • Mouse
  • Host Animal 2
  • Human
  • Specificity
  • Human IL13
  • Species Reactivity
  • Human
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • Anrukinzumab
  • Clone 2
  • IMA-026
  • Epitope 1
  • An epitope that binds IL-4Rα on Interleukin-13 (IL-13).
  • Epitope 2
  • An epitope that binds IL-13Rα1 and IL-13Rα2 on Interleukin-13 (IL-13).
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Interleukin 13

Target

  • Introduction
  • Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located on chromosome 5q31 with a length of 1.4kb. IL-13 and IL-4 exhibit a 30% of sequence similarity and have a similar structure.
  • Alternative Names
  • IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13;

Related Resources

  • Related Diseases

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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