Afuco™ Anti-IL13 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-219) (CAT#: AFC-TAB-219)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL13. It is a humanized monoclonal antibody and an experimental immunosuppresive drug for the treatment of asthma that cannot be adequately controlled with inhalable glucocorticoids.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, Neut, IF, IP, FC, FuncS
- Conjugate
- Unconjugated
- Trade name
- Tnx-650
- Generic Name
- Lebrikizumab
- Related Disease
- Idiopathic pulmonary fibrosis
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13;
- Gene ID
- 3596
- UniProt ID
- P35225
Related Resources
Please refer to Lebrikizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lebrikizumab.
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Lebrikizumab"
DrugMonitor™ Anti-Lebrikizumab Antibody (VS-1224-YC647)Lebrikizumab is a monoclonal antibody binding IL-13 with high affinity and slow off-rate, approved for treating moderate-to-severe atopic dermatitis. The DrugMonitor™ Anti-Lebrikizumab Antibody (VS-1224-YC647) is an anti-drug antibody (ADA) against Lebrikizumab. This drug-based antibody is raised in mice immunized with the Lebrikizumab. The anti-Lebrikizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Lebrikizumab in samples.
See other products for "IL13"
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-232 | Human Anti-IL13 Recombinant Antibody (clone M1295) | WB, IHC, FuncS | Human IgG |
| PABL-603 | Human Anti-IL13 Recombinant Antibody (clone C836) | Neut | Chimeric (mouse/human) IgG |
| PABL-605 | Human Anti-IL13 Recombinant Antibody (clone H2L6) | ELISA | Humanized IgG |
| PABL-606 | Human Anti-IL13 Recombinant Antibody (clone X836) | WB, ELISA, FuncS | Chimeric (mouse/human) IgG |
| VS3-FY2195 | Rabbit Anti-IL13 Recombinant Antibody (clone R25-8A-1) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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