Anti-Human IL-13 Recombinant Antibody scFv Fragment (CNTO 607) (CAT#: TAB-067ZJ-S(P))
CNTO607 binds human IL-13 with high affinity (Kd=15pM) and prevents binding of IL-13 to both IL-13Rα1 and IL-13Rα2. CNTO607 potently neutralizes the activity of IL-13 in a variety of bioassays, including cell survival, eotaxin production, and STAT6 signaling.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/475_E8_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42421/477_E8_1_blue_red_green.jpg
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Figure 4 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000169194-IL13
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- CNTO 607
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Inhibition; Functional Study
- Related Disease
- Allergic, Asthma and other atopic diseases
Target
Related Resources
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone CNTO 607"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1287z | Mouse Anti-IL13 Recombinant Antibody (clone 39B4) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| FN-189CQ | Rat Anti-Il13 Recombinant Antibody (clone CBL-1328) | FuncS, Neut, Block | Rat IgG1, κ |
| FN-190CQ | Rat Anti-Il13 Recombinant Antibody (clone CBL-1329) | ELISA, FuncS, FC | Rat IgG1, κ |
| HPAB-0286-YJ | Human Anti-IL13 Recombinant Antibody (HPAB-0286-YJ) | ELISA, Antagonist, FuncS | Human IgG1, κ |
| HPAB-0287-YJ | Mouse Anti-IL13 Recombinant Antibody (HPAB-0287-YJ) | ELISA, Neut, Inhib, FuncS | Mouse IgG1, κ |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218 | Anti-Human IL13 Recombinant Antibody (Tralokinumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG4 - lambda |
| TAB-067ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (CNTO 607) | ELISA, Inhib | Human antibody |
| TAB-068ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (01471/G6) | ELISA, Neut | Human antibody |
| TAB-069ZJ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (TAB-069ZJ-F(E)) | ELISA, Neut, FC | Human Fab |
| TAB-070ZJ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (TAB-070ZJ-F(E)) | ELISA, Neut, FC | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-232 | Human Anti-IL13 Recombinant Antibody (clone M1295); scFv Fragment | WB, IHC, FuncS | Human scFv |
| PSBL-600 | Human Anti-IL13 Recombinant Antibody (clone H2L6); scFv Fragment | ELISA | Humanized scFv |
| PSBL-601 | Mouse Anti-IL13 Recombinant Antibody (clone X836); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| PSBW-170 | Human Anti-IL13 Recombinant Antibody (clone CNTO607); scFv Fragment | ELISA, WB, Neut | Human scFv |
| HPAB-0045LY-S(P) | Human Anti-IL13 Recombinant Antibody (clone IMA-026); scfv Fragment | WB | Humanized scfv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-232 | Human Anti-IL13 Recombinant Antibody (clone M1295); Fab Fragment | WB, IHC, FuncS | Human Fab |
| HPAB-0226CQ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-0226CQ-F(E)) | ELISA, Neut, FC, FuncS | Human Fab |
| HPAB-0227CQ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (HPAB-0227CQ-F(E)) | ELISA, Neut, FC, FuncS | Human Fab |
| HPAB-0228CQ-F(E) | Mouse Anti-IL13 Recombinant Antibody (clone MJ2-7); Fab Fragment | ELISA, FC, Neut | Mouse Fab |
| HPAB-0229CQ-F(E) | Human Anti-IL13 Recombinant Antibody (clone huMJ2-7); Fab Fragment | ELISA, FC, Neut | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022ZJ | Anti-Human IL-13 Recombinant Antibody (C836) | ELISA | |
| TAB-023ZJ | Mouse Anti-IL13 Recombinant Antibody (TAB-023ZJ) | ELISA, Block | Mouse IgG |
| TAB-022ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (C836) | ELISA | |
| TAB-023ZJ-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-023ZJ-S(P)) | ELISA, Block | Mouse scFv |
| TAB-022ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (C836) | ELISA |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-043ZJ | Anti-Human IL-13 Recombinant Antibody (Lc6Hc2) | ELISA | Humanized antibody |
| TAB-044ZJ | Human Anti-IL13 Recombinant Antibody (TAB-044ZJ) | ELISA, Neut | Humanized IgG |
| TAB-045ZJ | Human Anti-IL13 Recombinant Antibody (TAB-045ZJ) | ELISA, Block | Humanized IgG |
| TAB-046ZJ | Human Anti-IL13 Recombinant Antibody (TAB-046ZJ) | ELISA, Block | Humanized IgG |
| TAB-043ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (Lc6Hc2) | ELISA | Humanized antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-094ZJ | Anti-Human IL-13 Recombinant Antibody (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1171CQ | Mouse Anti-IL13 Recombinant Antibody (clone B-B13) | ELISA, ELISPOT, Neut | Mouse IgG1 |
| NEUT-1172CQ | Mouse Anti-IL13 Recombinant Antibody (clone 10X28) | Neut, WB | Mouse IgG1 |
| NEUT-1173CQ | Mouse Anti-IL13 Recombinant Antibody (clone 15H10) | Neut | Mouse IgG2b |
| NEUT-1174CQ | Mouse Anti-IL13 Recombinant Antibody (clone 32116.11) | ELISA, Neut, WB | Mouse IgG1 |
| NEUT-1175CQ | Rat Anti-IL13 Recombinant Antibody (clone 5A2) | Neut | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1790 | Rabbit Anti-IL13 Recombinant Antibody (clone DS1790AB) | WB, ICC, FC, IP | Rabbit IgG |
| MOR-4610 | Rabbit Anti-IL13 Recombinant Antibody (clone TH123DS) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H05 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Anrukinzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-017ML | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Dectrekumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| AFC-TAB-219 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Lebrikizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
| AFC-TAB-218 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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