AbPlus™ Anti-IL17A Magnetic Beads (41809)
CAT#: VS-0424-XY147
The AbPlus Anti-IL17A Magnetic Beads (41809) is an innovative affinity resin which is bound with anti-IL17A specific antibody (41809). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IL17A protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows distinct positivity in peripheral leukocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_6.jpg
Normal Tissue
Figure 7 Tonsil
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (Karpas-707, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000112115-IL17A
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-IL17A specific antibody (41809)
- Target
- IL17A
- Immunogen
- Recombinant human IL17A (aa 20-155)
- Target Species
- Human
- Antibody Clone
- 41809
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
- Alternative Names
- IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
- Gene ID
- 3605
- UniProt ID
- Q16552
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Related Diseases
Inflammatory Bowel Diseases
Downloadable Resources
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-399CL | Human Anti-IL17A Recombinant Antibody (TAB-399CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
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| TAB-030ZJ | Mouse Anti-IL17A Recombinant Antibody (TAB-030ZJ) | ELISA, Neut | Mouse IgG |
| TAB-030ZJ-S(P) | Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-030ZJ-S(P)) | ELISA, Neut | Mouse scFv |
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| CAT | Product Name | Application | Type |
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| TAB-078ZJ-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-078ZJ-F(E)) | ELISA, Block, Neut | Human Fab |
| TAB-079ZJ-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-079ZJ-F(E)) | ELISA, Block, Neut | Human Fab |
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|---|---|---|---|
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| HPAB-0208-LSX | Human Anti-IL17A Recombinant Antibody (HPAB-0208-LSX) | ELISA, FuncS | Human IgG |
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| HPAB-0211-LSX | Rat Anti-IL17A Recombinant Antibody (HPAB-0211-LSX) | ELISA, FuncS | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0207-LSX-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0207-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0208-LSX-S(P) | Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0208-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0210-LSX-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0210-LSX-S(P)) | ELISA | Humanized scFv |
| HPAB-0211-LSX-S(P) | Rat Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0211-LSX-S(P)) | ELISA | Rat scFv |
| HPAB-0212-LSX-S(P) | Rat Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0212-LSX-S(P)) | ELISA | Rat scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-042CN | Mouse Anti-IL17A Recombinant Antibody (NS-042CN) | ELISA, FC | Mouse IgG |
| NS-042CN-F(E) | Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (NS-042CN-F(E)) | ELISA, FC | Mouse Fab |
| NS-042CN-S(P) | Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (NS-042CN-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0148-FY-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0148-FY-F(E)) | AG | Humanized Fab |
| HPAB-1045LY-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-1045LY-F(E)) | ELISA | Human Fab |
| HPAB-1046LY-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-1046LY-F(E)) | ELISA | Human Fab |
| HPAB-N0145-YC-F(E) | Human Anti-IL17A Recombinant Antibody (clone NOV006YC); Fab Fragment | ELISA | Humanized Fab |
| HPAB-N0146-YC-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-N0146-YC-F(E)) | ELISA, FuncS | Humanized Fab |
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