Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H08)

Name: Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H08)
SKU: AFC-TAB-H08
Rating: 5 (1 reviews)

CAT#: AFC-TAB-H08

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized antibody to Human IL17A

Gene Expression

Normal Tissue Figure 1 IHC staining of human small intestine

Immunohistochemical staining of human small intestine shows distinct positivity in peripheral leukocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_B_7_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_8_3.jpg

Normal Tissue Figure 4 Liver

Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_4.jpg

Normal Tissue Figure 5 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_5.jpg

Normal Tissue Figure 6 Testis

Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_6.jpg

Normal Tissue Figure 7 Tonsil

Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_8.jpg

RNA Expression Figure 8 RNA cell line category: Group enriched (Karpas-707, U-266/84)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000112115-IL17A

❮

❯

Specifications

Host Species
Human

Derivation
Humanized

Type
ADCC enhanced antibody

Specificity
IL17A (interleukin 17A, IL-17A) [Homo sapiens];

Species Reactivity
Human

Applications
ELISA, FC, IP, FuncS, IF, Neut

Conjugate
Unconjugated

Generic Name
Bimekizumab

Related Disease
Psoriasis

Product Property

Purity
>95% by SDS-PAGE

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
IL17A; interleukin 17A; CTLA8, IL17, interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); interleukin-17A; cytotoxic T lymphocyte associated protein 8; IL 17; IL 17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8;

Gene ID
3605

UniProt ID
Q16552

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for AFC-TAB-H08. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Biosimilar Overview

Please refer to Bimekizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Bimekizumab.

Related Diseases

Inflammatory Bowel Diseases

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-TAB-H08.pdf

MSDS

MSDS - AFC-TAB-H08.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "Bimekizumab"

DrugMonitor™ Anti-Bimekizumab Antibody (VS-1224-YC202)
Bimekizumab is a humanized monoclonal antibody directed towards IL-17, developed for plaque psoriasis treatment. The DrugMonitor™ Anti-Bimekizumab Antibody (VS-1224-YC202) is an anti-drug antibody (ADA) against Bimekizumab. This drug-based antibody is raised in mice immunized with the Bimekizumab. The anti-Bimekizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Bimekizumab in samples.

See other products for "IL17A"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
TAB-H57	Anti-Human IL17A Recombinant Antibody (Perakizumab)	WB, ELISA, IP, FC, FuncS, Neut, IF	IgG1 - kappa
TAB-H08	Anti-Human IL17A/IL17F Recombinant Antibody (TAB-H08)	ELISA, FC, IP, FuncS, IF, Neut, WB	IgG1 - kappa
TAB-048ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-048ZJ-S(P))	ELISA, Neut	Human scFv
TAB-048ZJ-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-048ZJ-F(E))	ELISA, Neut	Humanized Fab
TAB-458CQ	Anti-Human IL17A Recombinant Antibody (TAB-458CQ)	ELISA, IHC, FC, IP, IF, Inhib	IgG1, κ

CAT	Product Name	Application	Type
TAB-399CL	Human Anti-IL17A Recombinant Antibody (TAB-399CL)	ELISA	Human IgG

CAT	Product Name	Application	Type
PABL-237	Human Anti-IL17A Recombinant Antibody (clone CNTO7357)	WB, IHC, FuncS	Human IgG
PABL-238	Human Anti-IL17A Recombinant Antibody (clone Fab6785)	WB, ELISA, FuncS	Human IgG
HPAB-0207-LSX	Human Anti-IL17A Recombinant Antibody (HPAB-0207-LSX)	ELISA	Human IgG
HPAB-0208-LSX	Human Anti-IL17A Recombinant Antibody (HPAB-0208-LSX)	ELISA, FuncS	Human IgG
HPAB-0209-LSX	Human Anti-IL17A Recombinant Antibody (HPAB-0209-LSX)	ELISA	Chimeric IgG1, κ

CAT	Product Name	Application	Type
TAB-030ZJ	Mouse Anti-IL17A Recombinant Antibody (TAB-030ZJ)	ELISA, Neut	Mouse IgG
TAB-030ZJ-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-030ZJ-S(P))	ELISA, Neut	Mouse scFv
TAB-030ZJ-F(E)	Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-030ZJ-F(E))	ELISA, Neut	Mouse Fab

CAT	Product Name	Application	Type
TAB-078ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-078ZJ-S(P))	ELISA, Block, Neut	Human scFv
TAB-079ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-079ZJ-S(P))	ELISA, Block, Neut	Human scFv
TAB-080ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-080ZJ-S(P))	ELISA, Block, Neut	Human scFv
PABX-116	Recombinant Human Anti-Il-17A Antibody (CAT-2200)	WB, ELISA, FuncS	IgG
PABX-116-S (P)	Recombinant Human Anti-Il-17A Antibody scFv Fragment (CAT-2200)	WB, ELISA, FuncS	scFv

CAT	Product Name	Application	Type
Gly-077LC	Recombinant Anti-Human IL17A Antibody (Fc glycosylation)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
BRD-0289MZ	Chicken Anti-Interleukin-17a Polyclonal IgY	Indirect ELISA, WB	Chicken antibody

CAT	Product Name	Application	Type
NEUT-1202CQ	Mouse Anti-IL17A Recombinant Antibody (NEUT-1202CQ)	Neut	Mouse IgG2a
NEUT-1203CQ	Mouse Anti-IL17A Recombinant Antibody (NEUT-1203CQ)	Neut	Mouse IgG1
NEUT-1204CQ	Mouse Anti-IL17A Recombinant Antibody (clone 403D10.01)	Neut, FC	Mouse IgG1
NEUT-1205CQ	Mouse Anti-IL17A Recombinant Antibody (clone 408H6.01)	Neut, ELISA, FC	Mouse IgG2a
NEUT-1206CQ	Mouse Anti-IL17A Recombinant Antibody (clone 409H7.05)	Neut, FC	Mouse IgG1

CAT	Product Name	Application	Type
HPAB-0061-YC-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0061-YC-S(P))	ELISA, Neut	Humanized scFv
HPAB-0063-YC-S(P)	Human Anti-IL17A Recombinant Antibody (clone Antibody 7); scFv Fragment	FuncS	Human scFv
HPAB-0148-FY-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0148-FY-S(P))	AG	Human scFv
HPAB-0862-CN-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0862-CN-S(P))	ELISA, Neut	Mouse scFv
HPAB-0863-CN-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0863-CN-S(P))	ELISA, Neut	Mouse scFv

CAT	Product Name	Application	Type
NS-042CN	Mouse Anti-IL17A Recombinant Antibody (NS-042CN)	ELISA, FC	Mouse IgG
NS-042CN-F(E)	Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (NS-042CN-F(E))	ELISA, FC	Mouse Fab
NS-042CN-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (NS-042CN-S(P))	ELISA, FC	Mouse scFv

CAT	Product Name	Application	Type
HPAB-0866-CN-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0866-CN-F(E))	ELISA, Neut	Humanized Fab
HPAB-0867-CN-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0867-CN-F(E))	ELISA, Neut	Humanized Fab
HPAB-0868-CN-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0868-CN-F(E))	ELISA, Neut	Chimeric (mouse/human) Fab
HPAB-0869-CN-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0869-CN-F(E))	ELISA, Neut	Chimeric (mouse/human) Fab
HPAB-0240CQ-F(E)	Human Anti-IL17A Recombinant Antibody (clone h142); Fab Fragment	ELISA, Block	Human Fab

CAT	Product Name	Application	Type
AFC-TAB-458CQ	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-458CQ)	ELISA, IHC, FC, IP, IF, Inhib	ADCC enhanced antibody
AFC-TAB-069	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-069)	FC, IP, ELISA, Neut, FuncS, IF	ADCC enhanced antibody
AFC-TAB-H57	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H57)	ELISA, IP, FC, FuncS, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0424-XY147	AbPlus™ Anti-IL17A Magnetic Beads (41809)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0225-XY130	CytoStream™ Mouse Anti-IL17A Recombinant Antibody (VS-0225-XY130)	FC	Mouse IgG1, kappa

CAT	Product Name	Application	Type
VS-0325-FY96	Human Anti-IL17A (clone Antibody 7) scFv-Fc Chimera	ELISA, Inhib	Human IgG1, scFv-Fc

CAT	Product Name	Application
VS-0525-XY3489	Anti-IL17A Immunohistochemistry Kit	IHC
VS-0525-XY3490	Anti-Human IL17A Immunohistochemistry Kit	IHC
VS-0525-XY3491	Anti-Mouse IL17A Immunohistochemistry Kit	IHC

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 5 Anti-Human TNFSF11 Antibody (TAB-H18) in DB

Human Anti-TNFSF11 Recombinant Antibody (TAB-H18) (CAT# TAB-H18)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 3 Anti-Human NRP1 Therapeutic Antibody (TAB-264) in ELISA

Anti-Human NRP1 Recombinant Antibody (Vesencumab) (CAT# TAB-264)
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 2 Anti-Human CXCR4 Recombinant Antibody (TAB-H72) in HPLC

Human Anti-Human CXCR4 Recombinant Antibody (TAB-H72) (CAT# TAB-H72)
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 3 Anti-Human EGFR Antibody (TAB-003) in DB

Anti-Human EGFR Recombinant Antibody (Cetuximab) (CAT# TAB-003)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 3 Anti-Human HSP90 Recombinant Antibody (TAB-368CL) in ELISA

Anti-Human HSP90 Recombinant Antibody (CAT# TAB-368CL)
Application:

Figure 3 Anti-HIV-1 gp120 Antibody (PABL-163) in Dot Blot

Human Anti-HIV-1 gp120 Recombinant Antibody (clone 3bnc117) (CAT# PABL-163)
Application: Neut, ELISA, FuncS

Figure 2 Anti-C3b Antibody (PABL-420) in HPLC

Human Anti-C3b Recombinant Antibody (clone S77) (CAT# PABL-420)
Application: FuncS, Inhib, IP, ELISA

Figure 2 Anti-Mouse TIGIT Recombinant Antibody (TAB-0279CL) in HPLC

Hamster Anti-TIGIT Recombinant Antibody (TAB-0279CL) (CAT# TAB-0279CL)
Application: FuncS

Figure 2 Anti-Human TREM1 Recombinant Antibody (TAB-167CQ) in SDS-PAGE

Human Anti-TREM1 Recombinant Antibody (TAB-167CQ) (CAT# TAB-167CQ)
Application: ELISA, FC, WB, Block

Figure 2 Anti-Human CCP Recombinant Antibody (TAB-393CQ) in HPLC

Anti-Human CCP Recombinant Antibody (A02) (CAT# TAB-393CQ)
Application: ELISA, IHC

Figure 3 Anti-RABV G Recombinant Antibody (MRO-730LC) in WB

Anti-RABV G Recombinant Antibody (MRO-730LC) (CAT# MRO-730LC)
Application: ELISA, Neut, WB

Figure 2 Human Anti-RSV F Recombinant Antibody (MRO-878LC) in ELISA

Human Anti-RSV F Recombinant Antibody (MRO-878LC) (CAT# MRO-878LC)
Application: ELISA, Neut

Figure 4 Rat Anti-CD38 Recombinant Antibody (NEUT-349CQ) in ELISA

Rat Anti-CD38 Recombinant Antibody (clone NIMR-5) (CAT# NEUT-349CQ)
Application: Neut, FC, IHC-Fr, IP, BA

Figure 5 Anti-Human TNFRSF9 Recombinant Antibody (TAB-457CQ)-Low endotoxin in ELISA

Anti-Human TNFRSF9 Recombinant Antibody (TAB-457CQ) (CAT# TAB-457CQ)
Application: ELISA, IHC, FC, IP, IF, FuncS

Figure 2 Anti-Human ERBB2 Protein Antibody in ELISA

Mouse Anti-ERBB2 Recombinant Antibody (MOB-014LC) (CAT# MOB-014LC)
Application: ELISA, FC

Figure 3 Anti-IL2 Recombinant Antibody (PABC-506) in DB

Human Anti-IL2 Recombinant Antibody (PABC-506) (CAT# PABC-506)
Application: Inhib, ELISA, FC, FuncS

Figure 7 Human Anti-IAV HA Recombinant Antibody (HPAB-M0100-YC) in DB

Human Anti-HA Recombinant Antibody (HPAB-M0100-YC) (CAT# HPAB-M0100-YC)
Application: ELISA, FuncS

Figure 2 Mouse Anti-OxPL Recombinant Antibody (HPAB-0399-YJ) in HPLC

Mouse Anti-OxPL Recombinant Antibody (clone E06) (CAT# HPAB-0399-YJ)
Application: ELISA, FuncS

Figure 1 Mouse Anti-T7 RNA Polymerase Antibody (CBL-C001) (MOB-400CQ) in ELISA

Mouse Anti-T7 RNA Polymerase Antibody (CBL-C001) (CAT# MOB-400CQ)
Application: ELISA, WB

Figure 2 Human Anti-Insulin Recombinant Antibody (clone mAb48) (FAMAB-0224WJ) in ELISA

Human Anti-Insulin Recombinant Antibody (clone mAb48) (CAT# FAMAB-0224WJ)
Application: ELISA, WB

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.