Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H57)

Name: Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H57)
SKU: AFC-TAB-H57
Rating: 5 (1 reviews)

CAT#: AFC-TAB-H57

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human IL17A. It is a humanized monoclonal antibody designed for the treatment of arthritis. It binds to IL17A and acts as an immunomodulator.

Gene Expression

Normal Tissue Figure 1 IHC staining of human small intestine

Immunohistochemical staining of human small intestine shows distinct positivity in peripheral leukocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_B_7_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_8_3.jpg

Normal Tissue Figure 4 Liver

Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_4.jpg

Normal Tissue Figure 5 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_5.jpg

Normal Tissue Figure 6 Testis

Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_6.jpg

Normal Tissue Figure 7 Tonsil

Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_8.jpg

RNA Expression Figure 8 RNA cell line category: Group enriched (Karpas-707, U-266/84)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000112115-IL17A

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Specifications

Host Species
Human

Derivation
Humanized (from mouse)

Type
ADCC enhanced antibody

Specificity
IL17A (interleukin 17A, IL-17A) [Homo sapiens]

Species Reactivity
Human

Applications
ELISA, IP, FC, FuncS, Neut

Conjugate
Unconjugated

Generic Name
Perakizumab

Related Disease
Rheumatoid arthritis (RA)

Product Property

Purity
>95% by SDS-PAGE

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
IL-17; 3C1; IL17A; interleukin 17A; CTLA8, IL17, interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); interleukin-17A; cytotoxic T lymphocyte associated protein 8; IL 17; IL 17A; CTLA-8;

Gene ID
3605

UniProt ID
Q16552

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Biosimilar Overview

Please refer to Perakizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Perakizumab.

Related Diseases

Inflammatory Bowel Diseases

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-TAB-H57.pdf

MSDS

MSDS - AFC-TAB-H57.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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See other products for "perakizumab"

Anti-Human IL17A Recombinant Antibody (Perakizumab)
Recombinant Humanized (from mouse) antibody to Human IL17A. Perakizumab (INN) is a humanized monoclonal antibody designed for the treatment of arthritis. It binds to IL17A and acts as an immunomodulator.

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CAT	Product Name	Application	Type
TAB-H57	Anti-Human IL17A Recombinant Antibody (Perakizumab)	WB, ELISA, IP, FC, FuncS, Neut, IF	IgG1 - kappa
TAB-H08	Anti-Human IL17A/IL17F Recombinant Antibody (TAB-H08)	ELISA, FC, IP, FuncS, IF, Neut, WB	IgG1 - kappa
TAB-048ZJ	Human Anti-IL17A Recombinant Antibody (TAB-048ZJ)	ELISA, Neut	Humanized antibody
TAB-048ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-048ZJ-S(P))	ELISA, Neut	Human scFv
TAB-458CQ	Anti-Human IL17A Recombinant Antibody (TAB-458CQ)	ELISA, IHC, FC, IP, IF, Inhib	IgG1, κ

CAT	Product Name	Application	Type
TAB-399CL	Human Anti-IL17A Recombinant Antibody (TAB-399CL)	ELISA	Human IgG

CAT	Product Name	Application	Type
TAB-030ZJ	Mouse Anti-IL17A Recombinant Antibody (TAB-030ZJ)	ELISA, Neut	Mouse IgG
TAB-030ZJ-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-030ZJ-S(P))	ELISA, Neut	Mouse scFv
TAB-030ZJ-F(E)	Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-030ZJ-F(E))	ELISA, Neut	Mouse Fab

CAT	Product Name	Application	Type
TAB-078ZJ	Human Anti-IL17A Recombinant Antibody (TAB-078ZJ)	ELISA, Block, Neut	Human antibody
TAB-079ZJ	Human Anti-IL17A Recombinant Antibody (TAB-079ZJ)	ELISA, Block, Neut	Human IgG1
TAB-080ZJ	Human Anti-IL17A Recombinant Antibody (TAB-080ZJ)	ELISA, Block, Neut	Human antibody
TAB-078ZJ-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-078ZJ-F(E))	ELISA, Block, Neut	Human Fab
PABX-116	Recombinant Human Anti-Il-17A Antibody (CAT-2200)	WB, ELISA, FuncS	IgG

CAT	Product Name	Application	Type
Gly-077LC	Recombinant Anti-Human IL17A Antibody (Fc glycosylation)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
BRD-0289MZ	Chicken Anti-Interleukin-17a Polyclonal IgY	Indirect ELISA, WB	Chicken antibody

CAT	Product Name	Application	Type
NEUT-1202CQ	Mouse Anti-IL17A Recombinant Antibody (NEUT-1202CQ)	Neut	Mouse IgG2a
NEUT-1203CQ	Mouse Anti-IL17A Recombinant Antibody (NEUT-1203CQ)	Neut	Mouse IgG1
NEUT-1204CQ	Mouse Anti-IL17A Recombinant Antibody (clone 403D10.01)	Neut, FC	Mouse IgG1
NEUT-1205CQ	Mouse Anti-IL17A Recombinant Antibody (clone 408H6.01)	Neut, ELISA, FC	Mouse IgG2a
NEUT-1206CQ	Mouse Anti-IL17A Recombinant Antibody (clone 409H7.05)	Neut, FC	Mouse IgG1

CAT	Product Name	Application	Type
HPAB-0207-LSX	Human Anti-IL17A Recombinant Antibody (HPAB-0207-LSX)	ELISA	Human IgG
HPAB-0208-LSX	Human Anti-IL17A Recombinant Antibody (HPAB-0208-LSX)	ELISA, FuncS	Human IgG
HPAB-0209-LSX	Human Anti-IL17A Recombinant Antibody (HPAB-0209-LSX)	ELISA	Chimeric IgG1, κ
HPAB-0210-LSX	Human Anti-IL17A Recombinant Antibody (HPAB-0210-LSX)	ELISA	Humanized IgG1, κ
HPAB-0211-LSX	Rat Anti-IL17A Recombinant Antibody (HPAB-0211-LSX)	ELISA, FuncS	Rat IgG1, κ

CAT	Product Name	Application	Type
HPAB-0207-LSX-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0207-LSX-S(P))	ELISA	Mouse scFv
HPAB-0208-LSX-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0208-LSX-S(P))	ELISA	Mouse scFv
HPAB-0210-LSX-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0210-LSX-S(P))	ELISA	Humanized scFv
HPAB-0211-LSX-S(P)	Rat Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0211-LSX-S(P))	ELISA	Rat scFv
HPAB-0212-LSX-S(P)	Rat Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0212-LSX-S(P))	ELISA	Rat scFv

CAT	Product Name	Application	Type
NS-042CN	Mouse Anti-IL17A Recombinant Antibody (NS-042CN)	ELISA, FC	Mouse IgG
NS-042CN-F(E)	Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (NS-042CN-F(E))	ELISA, FC	Mouse Fab
NS-042CN-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (NS-042CN-S(P))	ELISA, FC	Mouse scFv

CAT	Product Name	Application	Type
HPAB-0148-FY-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0148-FY-F(E))	AG	Humanized Fab
HPAB-0240CQ-F(E)	Human Anti-IL17A Recombinant Antibody (clone h142); Fab Fragment	ELISA, Block	Human Fab
HPAB-2339LY-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-2339LY-F(E))	ELISA, Inhib	Human Fab
HPAB-2340LY-F(E)	Mouse Anti-IL17A Recombinant Antibody (clone CBL151); Fab Fragment	ELISA	Mouse Fab
HPAB-M0104-YC-F(E)	Human Anti-IL17A Recombinant Antibody (clone H1-2/L5); Fab Fragment	ELISA	Human Fab

CAT	Product Name	Application	Type
AFC-TAB-458CQ	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-458CQ)	ELISA, IHC, FC, IP, IF, Inhib	ADCC enhanced antibody
AFC-TAB-069	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-069)	FC, IP, ELISA, Neut, FuncS, IF	ADCC enhanced antibody
AFC-TAB-H08	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H08)	ELISA, FC, IP, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0424-XY147	AbPlus™ Anti-IL17A Magnetic Beads (41809)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0225-XY130	CytoStream™ Mouse Anti-IL17A Recombinant Antibody (VS-0225-XY130)	FC	Mouse IgG1, kappa

CAT	Product Name	Application	Type
VS-0325-FY96	Human Anti-IL17A (clone Antibody 7) scFv-Fc Chimera	ELISA, Inhib	Human IgG1, scFv-Fc

CAT	Product Name	Application
VS-0525-XY3489	Anti-IL17A Immunohistochemistry Kit	IHC
VS-0525-XY3490	Anti-Human IL17A Immunohistochemistry Kit	IHC
VS-0525-XY3491	Anti-Mouse IL17A Immunohistochemistry Kit	IHC

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