Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-069)
CAT#: AFC-TAB-069
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL17A. It is a human monoclonal antibody designed for the treatments of uveitis, rheumatoid arthritis, and psoriasis. It targets member A from the cytokine family of interleukin 17.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows distinct positivity in peripheral leukocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/ihc_selected.jpg
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Specifications
- Immunogen
- HuIL-17 coupled 10 KLH mixed 1:1 with huIL-17 in Gerbu adjuvant.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS, IF
- Conjugate
- Unconjugated
- Trade name
- Cosentyx
- Generic Name
- Secukinumab
- Related Disease
- Psoriatic arthritis (PSA)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Secukinumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Secukinumab.
Related Diseases
Inflammatory Bowel Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Secukinumab"
DrugMonitor™ Anti-Secukinumab Antibody (VS-1224-YC1069)Secukinumab is an immunomodulating agent and interleukin antagonist used to manage plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and other joint inflammatory disorders. The DrugMonitor™ Anti-Secukinumab Antibody (VS-1224-YC1069) is an anti-drug antibody (ADA) against Secukinumab. This drug-based antibody is raised in mice immunized with the Secukinumab. The anti-Secukinumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Secukinumab in samples.
See other products for "IL17A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H57 | Anti-Human IL17A Recombinant Antibody (Perakizumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG1 - kappa |
| TAB-H08 | Anti-Human IL17A/IL17F Recombinant Antibody (TAB-H08) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG1 - kappa |
| TAB-048ZJ | Human Anti-IL17A Recombinant Antibody (TAB-048ZJ) | ELISA, Neut | Humanized antibody |
| TAB-048ZJ-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-048ZJ-F(E)) | ELISA, Neut | Humanized Fab |
| TAB-458CQ | Anti-Human IL17A Recombinant Antibody (TAB-458CQ) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-399CL | Human Anti-IL17A Recombinant Antibody (TAB-399CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-030ZJ | Mouse Anti-IL17A Recombinant Antibody (TAB-030ZJ) | ELISA, Neut | Mouse IgG |
| TAB-030ZJ-S(P) | Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-030ZJ-S(P)) | ELISA, Neut | Mouse scFv |
| TAB-030ZJ-F(E) | Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-030ZJ-F(E)) | ELISA, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-078ZJ | Human Anti-IL17A Recombinant Antibody (TAB-078ZJ) | ELISA, Block, Neut | Human antibody |
| TAB-078ZJ-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-078ZJ-S(P)) | ELISA, Block, Neut | Human scFv |
| TAB-079ZJ-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-079ZJ-S(P)) | ELISA, Block, Neut | Human scFv |
| TAB-080ZJ-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-080ZJ-S(P)) | ELISA, Block, Neut | Human scFv |
| PABX-116 | Recombinant Human Anti-Il-17A Antibody (CAT-2200) | WB, ELISA, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-077LC | Recombinant Anti-Human IL17A Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0289MZ | Chicken Anti-Interleukin-17a Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1202CQ | Mouse Anti-IL17A Recombinant Antibody (NEUT-1202CQ) | Neut | Mouse IgG2a |
| NEUT-1203CQ | Mouse Anti-IL17A Recombinant Antibody (NEUT-1203CQ) | Neut | Mouse IgG1 |
| NEUT-1204CQ | Mouse Anti-IL17A Recombinant Antibody (clone 403D10.01) | Neut, FC | Mouse IgG1 |
| NEUT-1205CQ | Mouse Anti-IL17A Recombinant Antibody (clone 408H6.01) | Neut, ELISA, FC | Mouse IgG2a |
| NEUT-1206CQ | Mouse Anti-IL17A Recombinant Antibody (clone 409H7.05) | Neut, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0207-LSX | Human Anti-IL17A Recombinant Antibody (HPAB-0207-LSX) | ELISA | Human IgG |
| HPAB-0208-LSX | Human Anti-IL17A Recombinant Antibody (HPAB-0208-LSX) | ELISA, FuncS | Human IgG |
| HPAB-0209-LSX | Human Anti-IL17A Recombinant Antibody (HPAB-0209-LSX) | ELISA | Chimeric IgG1, κ |
| HPAB-0016-WJ | Human Anti-IL17A Recombinant Antibody (clone CJM112) | ELISA | Human IgG1, κ |
| HPAB-0059-WJ | Mouse Anti-IL17A Recombinant Antibody (HPAB-0059-WJ) | ELISA, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0207-LSX-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0207-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0208-LSX-S(P) | Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0208-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0210-LSX-S(P) | Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0210-LSX-S(P)) | ELISA | Humanized scFv |
| HPAB-0211-LSX-S(P) | Rat Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0211-LSX-S(P)) | ELISA | Rat scFv |
| HPAB-0212-LSX-S(P) | Rat Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0212-LSX-S(P)) | ELISA | Rat scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-042CN | Mouse Anti-IL17A Recombinant Antibody (NS-042CN) | ELISA, FC | Mouse IgG |
| NS-042CN-F(E) | Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (NS-042CN-F(E)) | ELISA, FC | Mouse Fab |
| NS-042CN-S(P) | Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (NS-042CN-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0148-FY-F(E) | Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0148-FY-F(E)) | AG | Humanized Fab |
| HPAB-0240CQ-F(E) | Human Anti-IL17A Recombinant Antibody (clone h142); Fab Fragment | ELISA, Block | Human Fab |
| HPAB-M0104-YC-F(E) | Human Anti-IL17A Recombinant Antibody (clone H1-2/L5); Fab Fragment | ELISA | Human Fab |
| HPAB-M0105-YC-F(E) | Human Anti-IL17A Recombinant Antibody (clone H1-2/L7); Fab Fragment | ELISA | Human Fab |
| HPAB-M0106-YC-F(E) | Human Anti-IL17A Recombinant Antibody (clone H3-1/L5); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-458CQ | Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-458CQ) | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| AFC-TAB-H08 | Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H08) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-H57 | Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H57) | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY147 | AbPlus™ Anti-IL17A Magnetic Beads (41809) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY130 | CytoStream™ Mouse Anti-IL17A Recombinant Antibody (VS-0225-XY130) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY96 | Human Anti-IL17A (clone Antibody 7) scFv-Fc Chimera | ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3489 | Anti-IL17A Immunohistochemistry Kit | IHC | |
| VS-0525-XY3490 | Anti-Human IL17A Immunohistochemistry Kit | IHC | |
| VS-0525-XY3491 | Anti-Mouse IL17A Immunohistochemistry Kit | IHC |
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