Afuco™ Anti-IL4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-221)
CAT#: AFC-TAB-221
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL4. It is a humanized monoclonal antibody for the treatment of asthma.
Gene Expression
Normal Tissue
Figure 1 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78477/168090_A_5_6.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113520-IL4
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF
- Conjugate
- Unconjugated
- Generic Name
- Pascolizumab
- Related Disease
- Allergy
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Pascolizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Pascolizumab.
Related Diseases
Asthma
Autoimmune Thyroid Disease
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Pascolizumab"
DrugMonitor™ Anti-Pascolizumab Antibody (VS-1224-YC888)Pascolizumab (SB 240683) is a humanized anti-interleukin-4 antibody with therapeutic potential in asthma treatment. The DrugMonitor™ Anti-Pascolizumab Antibody (VS-1224-YC888) is an anti-drug antibody (ADA) against Pascolizumab. This drug-based antibody is raised in mice immunized with the Pascolizumab. The anti-Pascolizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Pascolizumab in samples.
See other products for "Il4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-221 | Anti-Human IL4 Recombinant Antibody (TAB-221) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-666LC | Anti-human IL4 Recombinant Antibody (6A1) (TAB-666LC) | ELISA, FC | |
| TAB-666LC-S(P) | Anti-human IL4 scFv Fragment (6A1) | ELISA, FC | |
| TAB-666LC-F(E) | Anti-human IL4 Fab Fragment (6A1) | ELISA, FC | |
| MOB-0341MC | Recombinant Mouse Anti-IL4 Antibody | WB, Neut |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-667LC | Human Anti-IL4 Recombinant Antibody (TAB-667LC) | ELISA, FC | Human IgG1 |
| TAB-667LC-S(P) | Human Anti-IL4 Recombinant Antibody; scFv Fragment (TAB-667LC-S(P)) | ELISA, FC | Human scFv |
| TAB-667LC-F(E) | Human Anti-IL4 Recombinant Antibody; Fab Fragment (TAB-667LC-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1399CQ | Mouse Anti-IL4 Recombinant Antibody (clone CBL398) | Neut | Mouse IgG1 |
| NEUT-1400CQ | Mouse Anti-IL4 Recombinant Antibody (clone CBL335) | WB, ELISA, Neut | Mouse IgG2a |
| NEUT-1401CQ | Mouse Anti-IL4 Recombinant Antibody (clone 2G3) | ELISA, Neut, WB | Mouse IgG1, κ |
| NEUT-1402CQ | Rabbit Anti-IL4 Recombinant Antibody (NEUT-1402CQ) | Neut | Rabbit IgG |
| NEUT-1404CQ | Mouse Anti-IL4 Recombinant Antibody (clone 4D9) | ICC, IF, Neut, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1403CQ | Rat Anti-IL4 Recombinant Antibody (clone 25D2), Biotin | Block, ELISA, IHC, WB | Rat IgG1 |
| NEUT-1420CQ | Rat Anti-Il4 Recombinant Antibody (NEUT-1420CQ) | Block, DB | Rat IgG1 |
| NEUT-1428CQ | Rat Anti-Il4 Recombinant Antibody (clone 1D11) | Block, ELISA, FC, ICC, IF, WB | Rat IgG2b |
| NEUT-1429CQ | Rat Anti-Il4 Recombinant Antibody (clone 24G2) | Block, ELISA, ICC, IF, IHC, WB | Rat IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1812 | Rabbit Anti-IL4 Recombinant Antibody (clone DS1812AB) | ICC, WB | Rabbit IgG |
| MOR-4273 | Rabbit Anti-IL4 Recombinant Antibody (clone SI356DS) | ELISA | Rabbit IgG |
| MOR-4621 | Rabbit Anti-Il4 Recombinant Antibody (clone TH134DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0079-YC-S(P) | Mouse Anti-IL4 Recombinant Antibody (clone m3B9); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0080-YC-S(P) | Human Anti-IL4 Recombinant Antibody (clone hu3B9); scFv Fragment | ELISA | Humanized scFv |
| HPAB-1537WJ-S(P) | Human Anti-IL4 Recombinant Antibody; scFv Fragment (clone h25D2-9) | ELISA, WB, Neut | Human scFv |
| HPAB-1539WJ-S(P) | Mouse Anti-IL4 Recombinant Antibody; scFv Fragment (clone 3B9) | ELISA, WB, FC | Mouse scFv |
| HPAB-1540WJ-S(P) | Human Anti-IL4 Recombinant Antibody; scFv Fragment (clone ch3B9) | ELISA, WB, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0079-YC-F(E) | Mouse Anti-IL4 Recombinant Antibody (clone m3B9); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0080-YC-F(E) | Human Anti-IL4 Recombinant Antibody (clone hu3B9); Fab Fragment | ELISA | Humanized Fab |
| HPAB-1537WJ-F(E) | Human Anti-IL4 Recombinant Antibody; Fab Fragment (clone h25D2-9) | ELISA, WB, Neut | Human Fab |
| HPAB-1539WJ-F(E) | Mouse Anti-IL4 Recombinant Antibody; Fab Fragment (clone 3B9) | ELISA, WB, FC | Mouse Fab |
| HPAB-1540WJ-F(E) | Human Anti-IL4 Recombinant Antibody; Fab Fragment (clone ch3B9) | ELISA, WB, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1537WJ | Human Anti-IL4 Recombinant Antibody (clone h25D2-9) | ELISA, WB, Neut | Human IgG4 |
| HPAB-1539WJ | Mouse Anti-IL4 Recombinant Antibody (clone 3B9) | ELISA, WB, FC | Mouse IgG |
| HPAB-1540WJ | Human Anti-IL4 Recombinant Antibody (clone ch3B9) | ELISA, WB, FC | Chimeric (human/mouse) IgG |
| ZG-0766J | Rabbit Anti-IL4 Recombinant Antibody (clone 5D8) | ELISA, IHC | Rabbit IgG |
| VS3-FY754 | Recombinant Rabbit Anti-IL4 Antibody (clone R08-2A7) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1322 | Mouse Anti-IL4 Recombinant Antibody (VS3-WK1322) | ELISA, WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY141 | CytoStream™ Rat Anti-IL4 Recombinant Antibody (clone 11B11) | FC | Rat IgG1 |
| VS-0225-XY142 | CytoStream™ Mouse Anti-IL4 Recombinant Antibody (VS-0225-XY142) | ELISA, FC | Mouse IgG1, kappa |
| VS-0225-XY143 | CytoStream™ Rat Anti-IL4 Recombinant Antibody (VS-0225-XY143) | ELISA, FC, Neut, WB | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY131 | Human Anti-IL4 scFv-Fc Chimera (VS-0425-FY131) | ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3531 | Anti-Mouse IL4 Immunohistochemistry Kit | IHC |
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