Rabbit Anti-ITGA2 Recombinant Antibody (VS3-CJ711)
CAT#: VS3-CJ711
This product is a rabbit antibody that recognizes human, mouse, and rat ITGA2.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1358_H10_6_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1591_A6_2_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_6_6.jpg
Normal Tissue
Figure 8 Endometrium
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_6_3.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2
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Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat ITGA2
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC, IP, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Flow Cytometry.
Target
- Alternative Names
- BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2
- Gene ID
- 3673
- UniProt ID
- P17301
- Sequence Similarities
- Belongs to the integrin alpha chain family.
- Cellular Localization
- Membrane
- Protein Refseq
- NP_002194.2
- Function
- Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A.
(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "ITGA2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-251 | Anti-Human ITGA2 Recombinant Antibody (Vatelizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-714LC-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (TAB-714LC-S(P)) | ELISA | Mouse scFv |
| TAB-715LC-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (TAB-715LC-S(P)) | ELISA | Mouse scFv |
| TAB-716LC-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (TAB-716LC-S(P)) | ELISA | Mouse scFv |
| TAB-714LC-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (TAB-714LC-F(E)) | ELISA | Mouse Fab |
| TAB-715LC-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (TAB-715LC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2261MZ | Recombinant Mouse Anti-Human ITGA2 Antibody | WB | Mouse antibody |
| HPAB-0312-CN | Mouse Anti-ITGA2 Recombinant Antibody (HPAB-0312-CN) | ELISA, IHC, Block | Mouse IgG1, κ |
| HPAB-0313-CN | Human Anti-ITGA2 Recombinant Antibody (HPAB-0313-CN) | ELISA | Chimeric (mouse/human) IgG1, κ |
| HPAB-0314-CN | Human Anti-ITGA2 Recombinant Antibody (HPAB-0314-CN) | ELISA | Humanized IgG4, κ |
| FN-219CQ | Recombinant Armenian hamster Anti-ITGA2 Antibody (HMa2) | FC, FuncS | Armenian hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0293MZ | Chicken Anti-ITGA2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1542CQ | Recombinant Mouse Anti-ITGA2 Antibody (HAS-4) | FC, IHC-Fr, ICC, IP, BL | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1543CQ | Recombinant Mouse Anti-ITGA2 Antibody (NEUT-1543CQ) | FC, BL, IP, ELISA | IgG1, κ |
| NEUT-1544CQ | Recombinant Armenian Hamster Anti-Itga2 Antibody (HMα2) | FC, IF, IP, BL | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1871 | Hi-Affi™ Recombinant Rabbit Anti-ITGA2 Monoclonal Antibody (DS1871AB) | ICC, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0312-CN-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0312-CN-S(P)) | ELISA, IHC, Block | Mouse scFv |
| HPAB-0313-CN-S(P) | Human Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0313-CN-S(P)) | ELISA | Human scFv |
| HPAB-0314-CN-S(P) | Human Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0314-CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0312-CN-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0312-CN-F(E)) | ELISA, IHC, Block | Mouse Fab |
| HPAB-0313-CN-F(E) | Human Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0313-CN-F(E)) | ELISA | Human Fab |
| HPAB-0314-CN-F(E) | Human Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0314-CN-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-251 | Afuco™ Anti-ITGA2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-251) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY158 | AbPlus™ Anti-ITGA2 Magnetic Beads (HAS-4) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY288 | Mouse Anti-NHP ITGA2 Recombinant Antibody (clone AK7) | IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY149 | CytoStream™ Mouse Anti-ITGA2 Recombinant Antibody (VS-0225-XY149) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY137 | Human Anti-ITGA2 (clone Vatelizumab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC196 | Recombinant Anti-ITGA2 Vesicular Antibody, EV Displayed (VS-0425-YC196) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3615 | Anti-ITGA2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3616 | Anti-Mouse ITGA2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3617 | Anti-Human ITGA2 Immunohistochemistry Kit | IHC |
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