Human Anti-L1CAM Recombinant Antibody (clone Ab4); Fab Fragment

Name: Human Anti-L1CAM Recombinant Antibody (clone Ab4); Fab Fragment
SKU: HPAB-J0160-YC-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-J0160-YC-F(E)

This product is a monoclonal antibody Fab fragment that specifically binds to L1CAM (L1 cell adhesion molecule) protein expressed in human and mouse. This antibody can suppress the migration and proliferation of cancer cells.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10896/208_G1_2_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10896/207_G1_1_red_green.jpg

Subcellular Location Figure 3 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10896/206_G1_1_red_green.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuropil
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10896/27469_B_8_5.jpg

Normal Tissue Figure 5 Colon

Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%

Peripheral nerve/ganglion
Staining:

High

Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10896/27469_A_7_3.jpg

Normal Tissue Figure 6 Kidney

Collecting ducts
Staining:

High

Intensity: Strong
Quantity:>75%
Distal tubules
Staining:

High

Intensity: Strong
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10896/27469_A_8_5.jpg

RNA Expression Figure 7 RNA cell line category: Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+ RasG12V, HeLa, RH-30, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198910-L1CAM

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Specifications

Host Species
Human

Derivation
Human antibody library

Type
Human Fab

Specificity
Human L1CAM

Species Reactivity
Human, Mouse

Clone
Ab4

Applications
ELISA, FC, WB, FuncS

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1

Gene ID
3897

UniProt ID
P32004

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-J0160-YC-F(E).pdf

MSDS

MSDS - HPAB-J0160-YC-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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CAT
Product Name

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