Afuco™ Anti-MSLN ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-201)
CAT#: AFC-TAB-201
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Mesothelin. It is a chimeric monoclonal antibody designed for the treatment of cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17172/1276_A4_4_selected.jpg
Normal Tissue
Figure 2 Fallopian tube
Ciliated cells (cilia axoneme)
Staining:
High
Intensity: Strong
Ciliated cells (tip of cilia)
Staining:
High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2216/6076_A_7_7.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, EFO-21, HeLa, hTCEpi, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102854-MSLN
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Specifications
- Immunogen
- Spleen lymphocytes from mice fused with OVCAR-3, an ovarian tumorcell line derived from poorly differentiated adenocarcinoma of the ovary.
- Host Species
- Chimeric
- Derivation
- Chimeric (mouse/human)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- IP, IF, FuncS, FC, Neut, ELISA
- Conjugate
- Unconjugated
- Generic Name
- Amatuximab
- Related Disease
- Pancreatic cancers
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Amatuximab"
DrugMonitor™ Anti-Amatuximab Antibody (VS-1224-YC67)Amatuximab is a chimeric monoclonal antibody designed for cancer treatment, used in trials for Mesothelioma, Ovarian Cancer, Pancreatic Cancer, and other malignancies. The DrugMonitor™ Anti-Amatuximab Antibody (VS-1224-YC67) is an anti-drug antibody (ADA) against Amatuximab. This drug-based antibody is raised in mice immunized with the Amatuximab. The anti-Amatuximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Amatuximab in samples.
See other products for "MSLN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-009 | Recombinant Anti-human MSLN VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
| HPAB-M0391-YC | Recombinant Llama Anti-MSLN Single Domain Antibody (HPAB-M0391-YC) | ELISA, FC, IF | Llama VHH |
| HPAB-M0392-YC | Recombinant Llama Anti-MSLN Single Domain Antibody (HPAB-M0392-YC) | ELISA, FC, IF | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-201 | Anti-Human Mesothelin Recombinant Antibody (TAB-201) | IP, IF, FuncS, FC, Neut, ELISA, IHC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G052E | Anti-MSLN immunotoxin RG7787 (Fab)-PE | Cytotoxicity assay, Function study | |
| AGTO-G053E | Anti-Msln immunotoxin (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-L035E | anti-MSLN immunotoxin K1 (IgG)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L063E | anti-MSLN immunotoxin 8B35 (scFv)-PE | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-652 | Mouse Anti-MSLN Recombinant Antibody (clone MORAb-009); scFv Fragment | WB | Mouse scFv |
| HPAB-0041-CN-S(P) | Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0041-CN-S(P)) | FC, WB, ELISA | Mouse scFv |
| HPAB-0042-CN-S(P) | Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0042-CN-S(P)) | FC, WB, ELISA | Mouse scFv |
| HPAB-0043-CN-S(P) | Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0043-CN-S(P)) | FC, WB, ELISA | Mouse scFv |
| HPAB-0045-CN-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0045-CN-S(P)) | FC, WB, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0833CL-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0833CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0834CL-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0834CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0835CL-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0835CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0833CL-F(E) | Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0833CL-F(E)) | ELISA, FC | Human Fab |
| TAB-0834CL-F(E) | Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0834CL-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0376MZ | Chicken Anti-MSLN Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2302 | Hi-Affi™ Recombinant Rabbit Anti-MSLN Monoclonal Antibody (DS2302AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0861-CN | Human Anti-MSLN Recombinant Antibody (HPAB-0861-CN) | ELISA, FC, Neut | Human IgG, λ |
| HPAB-2427LY | Human Anti-MSLN Recombinant Antibody (HPAB-2427LY) | ELISA, FC, SPR | Human IgG |
| HPAB-2428LY | Human Anti-MSLN Recombinant Antibody (HPAB-2428LY) | ELISA, FC, SPR | Human IgG |
| HPAB-AP736-YC | Human Anti-MSLN Recombinant Antibody (HPAB-AP736-YC) | ELISA, FuncS | Human IgG |
| VS3-WK932 | Mouse Anti-MSLN Recombinant Antibody (VS3-WK932) | IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0101 | APC-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer | FCM | |
| MHC-CN0102 | PE-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer | FCM | |
| MHC-YF238 | A*02:01/Human Mesothelin (SLLFLLFSL) MHC Monomer | MHC Multimer | |
| MHC-YF239 | A*02:01/Human Mesothelin (VLPLTVAEV) MHC Monomer | MHC Multimer | |
| MHC-YF553 | A*01:01/Human Mesothelin (TLDTLTAFY) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0884-FY-S(P) | Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0884-FY-S(P)) | FC, IHC, ELISA | Mouse scFv |
| HPAB-0885-FY-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0885-FY-S(P)) | FC, IHC, ELISA | Human scFv |
| HPAB-0886-FY-S(P) | Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0886-FY-S(P)) | FC | Mouse scFv |
| HPAB-2735LY-F(E) | Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2735LY-F(E)) | ELISA, FC | Human Fab |
| HPAB-2736LY-F(E) | Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2736LY-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY69 | Human Anti-MSLN (clone SS) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC539 | Recombinant Anti-MSLN Vesicular Antibody, EV Displayed (VS-0425-YC539) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4533 | Anti-MSLN Immunohistochemistry Kit | IHC | |
| VS-0525-XY4534 | Anti-Mouse MSLN Immunohistochemistry Kit | IHC | |
| VS-0525-XY4535 | Anti-Rat MSLN Immunohistochemistry Kit | IHC |
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