MSLN
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0646-CN-S(P)) (HPAB-0646-CN-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody (TAB-0834CL) (TAB-0834CL)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FuncS, FC, SPR, Inhib
- Human Anti-MSLN Recombinant Antibody (HPAB-0646-CN) (HPAB-0646-CN)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-2427LY) (HPAB-2427LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, SPR
- Human Anti-MSLN Recombinant Antibody (HPAB-2428LY) (HPAB-2428LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, SPR
- PE-A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1049)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: PE
- APC-A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1050)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: APC
- FITC-A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1051)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: FITC
- APC-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer (MHC-CN0101)
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- Class: Class I
- Antigen: Mesothelin
- Antigen Species: Human
- Peptide: GQKMNAQAI
- Conjugate: APC
- Human Anti-MSLN Recombinant Antibody (HPAB-0706-CN) (HPAB-0706-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-0707-CN) (HPAB-0707-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: WB, ELISA, FC
- A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1052)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: Unconjugated
- Human Anti-MSLN Recombinant Antibody (HPAB-0708-CN) (HPAB-0708-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody (TAB-0835CL) (TAB-0835CL)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1, λ
- Application: ELISA, FC, FACS, Inhib
- PE-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer (MHC-CN0102)
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- Class: Class I
- Antigen: Mesothelin
- Antigen Species: Human
- Peptide: GQKMNAQAI
- Conjugate: PE
- Human Anti-MSLN Recombinant Antibody (clone M/YC-16) (HPAB-M0155-YC)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA, WB
- Human Anti-MSLN Recombinant Antibody (HPAB-M0157-YC) (HPAB-M0157-YC)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG
- Application: FuncS
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, IHC-Fr, WB
- Human Anti-MSLN Recombinant Antibody (HPAB-M0158-YC) (HPAB-M0158-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody (HPAB-M0159-YC) (HPAB-M0159-YC)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody (HPAB-M0160-YC) (HPAB-M0160-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody (HPAB-M0161-YC) (HPAB-M0161-YC)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0833CL-S(P)) (TAB-0833CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0834CL-S(P)) (TAB-0834CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0835CL-S(P)) (TAB-0835CL-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0833CL-F(E)) (TAB-0833CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0834CL-F(E)) (TAB-0834CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0835CL-F(E)) (TAB-0835CL-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, IHC
- Human Anti-MSLN Recombinant Antibody (TAB-0833CL) (TAB-0833CL)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FuncS, Activ, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-M0163-YC) (HPAB-M0163-YC)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG
- Application: FuncS
- Mouse Anti-MSLN Recombinant Antibody (HPAB-0042-CN) (HPAB-0042-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody (HPAB-M0162-YC) (HPAB-M0162-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
- Mouse Anti-MSLN Recombinant Antibody (HPAB-0041-CN) (HPAB-0041-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody (HPAB-0043-CN) (HPAB-0043-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody (HPAB-M0164-YC) (HPAB-M0164-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
- PE-A*02:01/Human MSLN (SLLFLLFSL) MHC Tetramer (MHC-CN1053)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: SLLFLLFSL
- Conjugate: PE
- Human Anti-MSLN Recombinant Antibody (HPAB-0044-CN) (HPAB-0044-CN)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody (HPAB-0884-FY) (HPAB-0884-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, WB
- APC-A*02:01/Human MSLN (SLLFLLFSL) MHC Tetramer (MHC-CN1054)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: SLLFLLFSL
- Conjugate: APC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC, IF
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0046-CN-F(E)) (HPAB-0046-CN-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0045-CN-F(E)) (HPAB-0045-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0043-CN-F(E)) (HPAB-0043-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0044-CN-F(E)) (HPAB-0044-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-1341-FY-F(E)) (HPAB-1341-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC, IF
- Human Anti-MSLN Recombinant Antibody (clone M/YC-16); Fab Fragment (HPAB-M0155-YC-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, WB
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- Target: mesothelin
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IL12-scFv
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0041-CN-S(P)) (HPAB-0041-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0042-CN-S(P)) (HPAB-0042-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0043-CN-S(P)) (HPAB-0043-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, WB, ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, IHC, FC, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0706-CN-S(P)) (HPAB-0706-CN-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0861-CN-S(P)) (HPAB-0861-CN-S(P))
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- Species Reactivity: Mouse
- Type: Human scFv
- Application: ELISA, FC, Neut
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0707-CN-S(P)) (HPAB-0707-CN-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FC
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0708-CN-S(P)) (HPAB-0708-CN-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0706-CN-F(E)) (HPAB-0706-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0707-CN-F(E)) (HPAB-0707-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0646-CN-F(E)) (HPAB-0646-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0708-CN-F(E)) (HPAB-0708-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB, ELISA, FC
- anti-MSLN immunotoxin K1 (IgG)-PE (AGTO-L035E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Anti-MSLN immunotoxin RG7787 (Fab)-PE (AGTO-G052E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- anti-MSLN immunotoxin 8B35 (scFv)-PE (AGTO-L063E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Anti-Msln immunotoxin (IgG)-PE (AGTO-G053E)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0042-CN-F(E)) (HPAB-0042-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0041-CN-F(E)) (HPAB-0041-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0046-CN-S(P)) (HPAB-0046-CN-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0442LY-F(E)) (HPAB-0442LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0443LY-F(E)) (HPAB-0443LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0045-CN-S(P)) (HPAB-0045-CN-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-2427LY-S(P)) (HPAB-2427LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0444LY-F(E)) (HPAB-0444LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0861-CN-F(E)) (HPAB-0861-CN-F(E))
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- Species Reactivity: Mouse
- Type: Human Fab
- Application: ELISA, FC, Neut
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0442LY-S(P)) (HPAB-0442LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0443LY-S(P)) (HPAB-0443LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0444LY-S(P)) (HPAB-0444LY-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human scfv
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2427LY-F(E)) (HPAB-2427LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2428LY-F(E)) (HPAB-2428LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0884-FY-F(E)) (HPAB-0884-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, IHC, ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0885-FY-F(E)) (HPAB-0885-FY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, IHC, ELISA
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0886-FY-F(E)) (HPAB-0886-FY-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse Fab
- Application: FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-1338-FY-F(E)) (HPAB-1338-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-1339-FY-F(E)) (HPAB-1339-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-1340-FY-F(E)) (HPAB-1340-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
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- Target: mesothelin
- Linker: cleavable di-peptide linker
- Drug: Duocarmycins
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
- Anti-Mesothelin-disulfide linker-DM4 ADC (ADC-145LCT)
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- Target: Mesothelin
- Linker: Cleavable, disulfide
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Target: MSLN
- Linker: protease-cleavable peptide linker
- Drug: MMAE (Monomethyl auristatin E)
- Anti-mesothelin ADC (ADC-126LZY)
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- Target: mesothelin
- Anti-MSLN (clone h7D9.v3)-mc-MMAF ADC (ADC-225LZY)
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- Target: MSLN
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-MSLN (clone h7D9.v3)-mc-vc-PABC-MMAE ADC (ADC-226LZY)
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- Target: MSLN
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
- Anti-MSLN (clone h7D9.v3)-mc-vc-PABC-MMAF ADC (ADC-227LZY)
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- Target: MSLN
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-mesothelin-SPDB-DM4 ADC (ADC-017LZY)
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- Target: mesothelin
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Chicken Anti-MSLN Polyclonal IgY (BRD-0376MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
- Anti-Mesothelin (MF-T)-DM4 ADC (BAY 94-9343) (ADC-L009)
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- Target: mesothelin
- Linker: disulfide
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4- methyl-1-oxopentyl)maytansine)
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
