MSLN
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB
- Human Anti-MSLN Recombinant Antibody (TAB-0834CL) (TAB-0834CL)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, FuncS, FC, SPR, Inhib
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0646-CN-S(P)) (HPAB-0646-CN-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-0861-CN) (HPAB-0861-CN)
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- Species Reactivity: Mouse
- Type: Human IgG, λ
- Application: ELISA, FC, Neut
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA, IHC
- Mouse Anti-MSLN Recombinant Antibody (HPAB-0041-CN) (HPAB-0041-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody (HPAB-0042-CN) (HPAB-0042-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody (TAB-0835CL) (TAB-0835CL)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1, λ
- Application: ELISA, FC, FACS, Inhib
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0833CL-S(P)) (TAB-0833CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0834CL-S(P)) (TAB-0834CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0835CL-S(P)) (TAB-0835CL-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0833CL-F(E)) (TAB-0833CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0834CL-F(E)) (TAB-0834CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (TAB-0835CL-F(E)) (TAB-0835CL-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-0442LY) (HPAB-0442LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody (HPAB-0443LY) (HPAB-0443LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody (HPAB-0444LY) (HPAB-0444LY)
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody (HPAB-0706-CN) (HPAB-0706-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-0707-CN) (HPAB-0707-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-0708-CN) (HPAB-0708-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: WB, ELISA, FC
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IP, IF, FuncS, FC, Neut, ELISA
- PE-A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1049)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: PE
- APC-A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1050)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: APC
- FITC-A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1051)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: FITC
- A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer (MHC-CN1052)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: TLDTLTAFY
- Conjugate: Unconjugated
- PE-A*02:01/Human MSLN (SLLFLLFSL) MHC Tetramer (MHC-CN1053)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: SLLFLLFSL
- Conjugate: PE
- APC-A*02:01/Human MSLN (SLLFLLFSL) MHC Tetramer (MHC-CN1054)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: SLLFLLFSL
- Conjugate: APC
- FITC-A*02:01/Human MSLN (SLLFLLFSL) MHC Tetramer (MHC-CN1055)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: SLLFLLFSL
- Conjugate: FITC
- A*02:01/Human MSLN (SLLFLLFSL) MHC Tetramer (MHC-CN1056)
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- Class: Class I
- Antigen: MSLN
- Antigen Species: Human
- Peptide: SLLFLLFSL
- Conjugate: Unconjugated
- Human Anti-MSLN Recombinant Antibody (HPAB-2427LY) (HPAB-2427LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, SPR
- Human Anti-MSLN Recombinant Antibody (HPAB-2428LY) (HPAB-2428LY)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC, SPR
- APC-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer (MHC-CN0101)
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- Class: Class I
- Antigen: Mesothelin
- Antigen Species: Human
- Peptide: GQKMNAQAI
- Conjugate: APC
- PE-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer (MHC-CN0102)
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- Class: Class I
- Antigen: Mesothelin
- Antigen Species: Human
- Peptide: GQKMNAQAI
- Conjugate: PE
- Human Anti-MSLN Recombinant Antibody (clone M/YC-16) (HPAB-M0155-YC)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: ELISA, WB
- Human Anti-MSLN Recombinant Antibody (HPAB-M0157-YC) (HPAB-M0157-YC)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG
- Application: FuncS
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, IHC-Fr, WB
- Human Anti-MSLN Recombinant Antibody (HPAB-1338-FY) (HPAB-1338-FY)
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- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody (TAB-0833CL) (TAB-0833CL)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA, FuncS, Activ, FC
- Human Anti-MSLN Recombinant Antibody (HPAB-1339-FY) (HPAB-1339-FY)
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- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA, FC
- Mouse Anti-MSLN Recombinant Antibody (clone MN); scFv Fragment (HPAB-1780-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0041-CN-S(P)) (HPAB-0041-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0042-CN-S(P)) (HPAB-0042-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0043-CN-S(P)) (HPAB-0043-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0045-CN-S(P)) (HPAB-0045-CN-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0046-CN-S(P)) (HPAB-0046-CN-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0861-CN-S(P)) (HPAB-0861-CN-S(P))
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- Species Reactivity: Mouse
- Type: Human scFv
- Application: ELISA, FC, Neut
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0646-CN-F(E)) (HPAB-0646-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-2427LY-S(P)) (HPAB-2427LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0884-FY-S(P)) (HPAB-0884-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, IHC, ELISA
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0885-FY-S(P)) (HPAB-0885-FY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC, IHC, ELISA
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-2428LY-S(P)) (HPAB-2428LY-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0886-FY-S(P)) (HPAB-0886-FY-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: FC
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC, IF
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0044-CN-F(E)) (HPAB-0044-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, WB, ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0045-CN-F(E)) (HPAB-0045-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0046-CN-F(E)) (HPAB-0046-CN-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2427LY-F(E)) (HPAB-2427LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2428LY-F(E)) (HPAB-2428LY-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: ELISA, FC, IF
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0444LY-F(E)) (HPAB-0444LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody (clone M/YC-16); scFv Fragment (HPAB-M0155-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0157-YC-S(P)) (HPAB-M0157-YC-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0158-YC-S(P)) (HPAB-M0158-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0159-YC-S(P)) (HPAB-M0159-YC-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0160-YC-S(P)) (HPAB-M0160-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0161-YC-S(P)) (HPAB-M0161-YC-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0162-YC-S(P)) (HPAB-M0162-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0163-YC-S(P)) (HPAB-M0163-YC-S(P))
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- Species Reactivity: Human
- Type: Rabbit scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0164-YC-S(P)) (HPAB-M0164-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-1338-FY-F(E)) (HPAB-1338-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-1339-FY-F(E)) (HPAB-1339-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC
- Anti-MSLN immunotoxin RG7787 (Fab)-PE (AGTO-G052E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Anti-Msln immunotoxin (IgG)-PE (AGTO-G053E)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
- anti-MSLN immunotoxin K1 (IgG)-PE (AGTO-L035E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- anti-MSLN immunotoxin 8B35 (scFv)-PE (AGTO-L063E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0041-CN-F(E)) (HPAB-0041-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0042-CN-F(E)) (HPAB-0042-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, WB, ELISA
- Mouse Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0043-CN-F(E)) (HPAB-0043-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, WB, ELISA
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, IHC, FC, FuncS
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- Target: mesothelin
- Species Reactivity: Human
- Cytokine 1: IL12
- Host: Mouse
- Cytokine 1 Species: Human
- Molecule Class: IL12-scFv
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0706-CN-S(P)) (HPAB-0706-CN-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FC
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0707-CN-S(P)) (HPAB-0707-CN-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FC
- Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0708-CN-S(P)) (HPAB-0708-CN-S(P))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0706-CN-F(E)) (HPAB-0706-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB, ELISA, FC
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0442LY-F(E)) (HPAB-0442LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IHC, WB
- Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-0443LY-F(E)) (HPAB-0443LY-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC, IHC, WB
- Anti-Mesothelin (MF-T)-DM4 ADC (BAY 94-9343) (ADC-L009)
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- Target: mesothelin
- Linker: disulfide
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4- methyl-1-oxopentyl)maytansine)
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- Target: mesothelin
- Linker: cleavable di-peptide linker
- Drug: Duocarmycins
- Anti-Mesothelin-disulfide linker-DM4 ADC (ADC-145LCT)
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- Target: Mesothelin
- Linker: Cleavable, disulfide
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
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- Target: MSLN
- Linker: protease-cleavable peptide linker
- Drug: MMAE (Monomethyl auristatin E)
- Anti-mesothelin-SPDB-DM4 ADC (ADC-017LZY)
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- Target: mesothelin
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-mesothelin ADC (ADC-126LZY)
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- Target: mesothelin
- Anti-MSLN (clone h7D9.v3)-mc-MMAF ADC (ADC-225LZY)
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- Target: MSLN
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-MSLN (clone h7D9.v3)-mc-vc-PABC-MMAE ADC (ADC-226LZY)
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- Target: MSLN
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAE (monomethyl auristatin E)
- Anti-MSLN (clone h7D9.v3)-mc-vc-PABC-MMAF ADC (ADC-227LZY)
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- Target: MSLN
- Linker: mc-VC-PABC (maleimidocaproyl valine-citrulline-p-aminobenzyl carbamoyl)
- Drug: MMAF (monomethyl auristatin F)
- Chicken Anti-MSLN Polyclonal IgY (BRD-0376MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
Mesothelin (MSLN) is a glycosylphosphatidylinositol (GPI)-anchored protein expressed on mesothelial cells of the pleura, peritoneum, and pericardium, with low normal tissue expression. It is overexpressed in mesothelioma, pancreatic cancer, ovarian cancer, and lung adenocarcinoma, promoting cell adhesion and tumor progression. MSLN's restricted normal tissue expression and high tumor specificity make it an attractive target.

