This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human RSV. Palivizumab is a monoclonal antibody produced by recombinant DNA technology. It is used in the prevention of respiratory syncytial virus (RSV) infections. It is recommended for infants that are high-risk because of prematurity or other medical problems such as congenital heart disease. Palivizumab is a humanized monoclonal antibody (IgG) directed against an epitope in the A antigenic site of the F protein of RSV.
Figure 1 Afuco Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced (AFC-TAB-009) in SDS-PAGE
SDS-PAGE analysis of AFC-TAB-009 in reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result, different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
The purity of AFC-TAB-009 was greater than 95% as determined by SDS-PAGE.
Figure 2 Afuco Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced (AFC-TAB-009) in HPLC
The purity of AFC-TAB-009 was greater than 94% as determined by SEC-HPLC
Figure 3 Afuco Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced (AFC-TAB-009) in Lectin WB
Western blot analysis of AFC-TAB-009 was performed and fucose was detected by AOL-Biotin and SA-HRP. The result was negative, which indicates that there is almost no fucose produced.
Lane 1: Reducing AFC-TAB-009 (2 μg)
Lane 2: Reducing positive control antibody (2 μg)
Figure 4 Afuco Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced (AFC-TAB-009) in Lectin ELISA
Lectin ELISA analysis of AFC-TAB-009 was conducted and fucose was detected using AOL-Biotin and SA-HRP
The result indicates that there is almost no fucose produced.
Figure 5 Afuco Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced (AFC-TAB-009) in WB
Western blot analysis of AFC-TAB-009 was performed by loading RSV F.
AFC-TAB-009 incubation concentration: 2 ng/μL.
The secondary antibody: HRP-anti-human IgG
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)
Figure 6 Afuco Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced (AFC-TAB-009) in ELISA
ELISA analysis of AFC-TAB-009 was performed by coating with RSV F.
The secondary antibody: HRP-anti-human IgG
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
Anti-RSV Recombinant Antibody (Palivizumab)Recombinant monoclonal antibody to Human RSV. Palivizumab is a monoclonal antibody produced by recombinant DNA technology. It is used in the prevention of respiratory syncytial virus (RSV) infections. It is recommended for infants that are high-risk because of prematurity or other medical problems such as congenital heart disease. Palivizumab is a humanized monoclonal antibody (IgG) directed against an epitope in the A antigenic site of the F protein of RSV.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-009 | Anti-RSV Recombinant Antibody (Palivizumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
TAB-709 | Anti-RSV glycoprotein F Recombinant Antibody (Motavizumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
MRO-1209LC | Anti-HRSV F Recombinant Antibody (MEDI-493) | ELISA, Neut, PK | Humanized antibody |
MRO-1209LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (MEDI-493) | ELISA | Humanized antibody |
MRO-1209LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (MEDI-493) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-358CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-358CT-S(P)) | ELISA, WB, Neut, IF, FC | Human scFv |
TAB-361CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-361CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
TAB-362CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-362CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
TAB-363CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-363CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
TAB-364CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-364CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-878LC-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (MRO-878LC-S(P)) | ELISA, Neut | Human scFv |
PSBC-276 | Recombinant Mouse Anti-RSV F Antibody scFv Fragment (5C4) | ELISA, Neut | Mouse scFv |
HPAB-0105-WJ-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (HPAB-0105-WJ-S(P)) | ELISA, WB | Human scFv |
PABJ-0100-S(P) | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6); scFv Fragment | ELISA, Neut | Mouse scFv |
PABJ-0166-S(P) | Human Anti-RSV F Recombinant Antibody (clone RSD5); scFv Fragment | ELISA, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-878LC-F(E) | Human Anti-RSV F Recombinant Antibody; Fab Fragment (MRO-878LC-F(E)) | ELISA, Neut | Human Fab |
PFBC-276 | Recombinant Mouse Anti-RSV F Antibody Fab Fragment (5C4) | ELISA, Neut | Mouse Fab |
PFBC-494 | Recombinant Human Anti-RSV F Antibody Fab Fragment (14N4) | ELISA, Neut | Human Fab |
HPAB-0105-WJ-F(E) | Human Anti-RSV F Recombinant Antibody; Fab Fragment (HPAB-0105-WJ-F(E)) | ELISA, WB | Human Fab |
PABJ-0100-F(E) | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6); Fab fragment | ELISA, Neut | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-1210LC | Anti-HRSV F Recombinant Antibody (C11) | ELISA | Mouse Antibody |
MRO-1210LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (C11) | ELISA | Mouse Antibody |
MRO-1211LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (C13) | ELISA | Mouse Antibody |
MRO-1210LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (C11) | ELISA | Mouse Antibody |
MRO-1211LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (C13) | ELISA | Mouse Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0293CQ | Human Anti-RSV F Recombinant Antibody (HPAB-0293CQ) | ELISA, Neut, FuncS | Human IgG1 |
PABC-276 | Recombinant Mouse Anti-RSV F Antibody (5C4) | ELISA, Neut, DB, FC | Mouse IgG |
PABS-0157 | Human Anti-RSV F Recombinant Antibody (clone C57) | FC, ELISA | Human IgG |
PABS-0166 | Human Anti-RSV F Recombinant Antibody (clone MEDI8897) | ELISA, Neut, FuncS | Human IgG |
PABJ-0166 | Human Anti-RSV F Recombinant Antibody (clone RSD5) | ELISA, Neut | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-709 | Afuco™ Anti-RSV F ADCC Recombinant Antibody (Motavizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YC250 | H-2Kd/Respiratory syncytial virus Fusion protein (F) (KYKNAVTEL) MHC Pentamer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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