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    Afuco™ Anti-RTN4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-242) (CAT#: AFC-TAB-242)

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to RTN-4. It is an immunomodulator. It binds to reticulon 4.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human testis
    Figure 2 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong cytoplasmic positivity in seminiferous ducts cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6_selected.jpg
    Figure 3 IHC staining of human testis
    Figure 3 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_A_6_6_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_B_8_5.jpg
    Figure 5 Cerebellum
    Figure 5 Cerebellum
    (Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5388/13996_B_7_8.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Enterocytes - Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25% Peripheral nerve/ganglion Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_9_3.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/23977/54863_A_4_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (HHSteC)
    Figure 8 RNA cell line category: Cell line enhanced (HHSteC)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115310-RTN4

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • ELISA, FC, IP, FuncS, IF, Neut
    • Conjugate
    • Unconjugated
    • Generic Name
    • Atinumab
    • Related Disease
    • Spinal cord injury, acute

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • NOGO; NSP CL; foocen; Human NogoA; reticulon 5; My043 protein; neurite outgrowth inhibitor; neurite growth inhibitor 220; neuroendocrine-specific protein C homolog; NSP; NOGOC; RTN-X; NOGO-A; NSP-C

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "RTN4"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Human Antibody Products Mouse Antibody Products Chimeric Antibody Products Humanized Antibody Products Rabbit Monoclonal Antibody Products Fab Antibody Products ScFv Antibody Products ADCC Enhanced Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-2437z Mouse Anti-RTN4 Recombinant Antibody (clone 28B12) WB, ELISA, IF, IP Mouse IgM, κ
    MOB-2424CT Recombinant Mouse anti-Human RTN4 Monoclonal antibody (9XH27) WB, IHC-P, IHC-Fr
    MOB-186CQ Mouse Anti-RTN4 Antibody ELISA, WB Mouse IgG1
    HPAB-0047-WJ Mouse Anti-RTN4 Recombinant Antibody (clone 6F2) ELISA, WB, Inhib, IHC, IF Mouse IgG
    MRO-1101-CN Recombinant Rabbit Anti-RTN4 Monoclonal Antibody (JM02-34) WB, IF, IHC, IP, FC Rabbit IgG

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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