AbPlus™ Anti-SNCA Magnetic Beads (VS-0724-YC791)
CAT#: VS-0724-YC791
The AbPlus Anti-SNCA Magnetic Beads (VS-0724-YC791) is an innovative affinity resin which is bound with anti-SNCA specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SNCA protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 High expression in cerebral cortex
Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164874_B_9_5.jpg
Normal Tissue
Figure 2 Colon
Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10877/164900_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164893_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164893_A_6_6.jpg
Normal Tissue
Figure 5 Bone marrow
Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5459/164874_B_4_4.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HEL, HUVEC TERT2, RT4, SK-MEL-30, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000145335-SNCA
❮
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SNCA specific antibody
- Target
- SNCA
- Immunogen
- Recombinant human SNCA/alpha-Synuclein, aa 1-140.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
- Alternative Names
- Synuclein Alpha; Synuclein, Alpha (Non A4 Component Of Amyloid Precursor); Alpha-Synuclein; PARK1; NACP; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Non A4 Component Of Amyloid Precursor; Non-A4 Component Of Amyloid Precursor;
- Gene ID
- 6622
- UniProt ID
- P37840
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
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| IAB-B031(T) | Recombinant Anti-human SNCA Intrabody [Tat] | ELISA, IF, Neut, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-086 | Recombinant Anti-SNCA VHH Single Domain Antibody (PNBL-086) | WB, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0740CLV | Rabbit Anti-SNCA Recombinant Antibody (TAB-0740CLV) | ELISA | Chimeric antibody (mouse/rabbit) |
| TAB-0740CLV-F(E) | Rabbit Anti-SNCA Recombinant Antibody; Fab Fragment (TAB-0740CLV-F(E)) | ELISA | Chimeric antibody (mouse/rabbit) |
| TAB-0740CLV-S(P) | Rabbit Anti-SNCA Recombinant Antibody; scFv Fragment (TAB-0740CLV-S(P)) | ELISA | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0741CLV | Mouse Anti-SNCA Recombinant Antibody (TAB-0741CLV) | IF | Mouse IgG1 |
| TAB-0742CLV | Mouse Anti-SNCA Recombinant Antibody (TAB-0742CLV) | ELISA, ICC, FuncS, IHC, Block | Mouse IgG2a |
| TAB-0743CLV | Mouse Anti-SNCA Recombinant Antibody (TAB-0743CLV) | ELISA | Mouse IgG2a |
| TAB-0744CLV | Mouse Anti-SNCA Recombinant Antibody (TAB-0744CLV) | ELISA | Mouse IgG1 |
| TAB-0745CLV | Mouse Anti-SNCA Recombinant Antibody (TAB-0745CLV) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1977CQ | Recombinant Human Anti-SNCA Antibody (NAC32) | IHC, WB, BL | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0154 | Hi-Affi™ Recombinant Rabbit Anti-alpha + beta Synuclein Monoclonal Antibody (DS154AB) | FC, WB, ICC, IF | IgG |
| MOR-3354 | Hi-Affi™ Recombinant Rabbit Anti-SNCA Monoclonal Antibody (DS3354AB) | IHC, ICC, FC, IP | IgG |
| MOR-4530 | Hi-Affi™ Recombinant Rabbit Anti-SNCA Monoclonal Antibody (TH38DS) | WB, IF, ICC, IHC-P, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-005CN | Mouse Anti-SNCA Recombinant Antibody (NS-005CN) | WB, ELISA, FC | Mouse IgG2a |
| NS-088CN | Mouse Anti-SNCA Recombinant Antibody (NS-088CN) | WB, ELISA, IHC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-005CN-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (NS-005CN-F(E)) | WB, ELISA, FC | Mouse Fab |
| NS-088CN-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (NS-088CN-F(E)) | WB, ELISA, IHC | Mouse Fab |
| FAMAB-0260-CN-F(E) | Human Anti-SNCA Recombinant Antibody (clone D10); Fab Fragment | ELISA | Human Fab |
| FAMAB-0261-CN-F(E) | Human Anti-SNCA Recombinant Antibody (clone 6E); Fab Fragment | ELISA | Human Fab |
| HPAB-M0696-YC-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (HPAB-M0696-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-005CN-S(P) | Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (NS-005CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| NS-088CN-S(P) | Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (NS-088CN-S(P)) | WB, ELISA, IHC | Mouse scFv |
| HPAB-0023-FY-S(P) | Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-0023-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-M0696-YC-S(P) | Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-M0696-YC-S(P)) | ELISA, FuncS | Mouse scFv |
| HPAB-0753-WJ-S(P) | Human Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-0753-WJ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0023-FY | Mouse Anti-SNCA Recombinant Antibody (HPAB-0023-FY) | ELISA | Mouse IgG1, κ |
| MRO-0071-CN | Recombinant Rabbit Anti-SNCA Monoclonal Antibody (JB42-33) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-FY1367 | Recombinant Rabbit Anti-SNCA Antibody (clone R01-4E1) | WB, IHC-P, IP | Rabbit IgG |
| VS7-0425-WR897 | Mouse Anti-SNCA Monoclonal Antibody (clone 2B2D1) | IHC | Mouse IgG1 |
| VS7-0425-WR898 | Mouse Anti-SNCA Monoclonal Antibody (VS7-0425-WR898) | WB, IHC-P, IF, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY244 | AbPlus™ Anti-SNCA Magnetic Beads (JB42-33) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY32 | Human Anti-SNCA scFv-Fc Chimera (VS-0325-FY32) | ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2129 | Anti-SNCA Immunohistochemistry Kit | IHC | |
| VS-0525-XY6773 | Anti-Mouse SNCA Immunohistochemistry Kit | IHC | |
| VS-0525-XY6772 | Anti-Human SNCA Immunohistochemistry Kit | IHC | |
| VS-0525-XY6774 | Anti-Rat SNCA Immunohistochemistry Kit | IHC |
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