Recombinant Anti-human SNCA Intrabody [(D-Arg)₉] (CAT#: IAB-B031(A))

• Immunogen
• human synuclein, alpha (non A4 component of amyloid precursor)

• Host Species
• human

• Type
• scFv-(D-Arg)₉

• Cell Penetrating Peptide
• (D-Arg)₉
  It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.

• Species Reactivity
• human

• Applications
• Antibody assay: Flow Cytometry; Immunofluorescence; Functional studies

• Purity
• >95%, by SDS-PAGE, under reducing conditions

• Storage
• Store at -20°C. Open under aseptic conditions.

• Alternative Names
• SNCA; synuclein, alpha (non A4 component of amyloid precursor); PD1; NACP; PARK1; PARK4; alpha-synuclein; synuclein alpha-140; non A-beta component of AD amyloid

• Gene ID
• 6622

• UniProt ID
• P37840

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