Rabbit Anti-SPP1 Recombinant Antibody (VS3-FY2881)
CAT#: VS3-FY2881
The anti-SPP1 antibody is a rabbit recombinant monoclonal antibody that has been designed to bind the human SPP1 protein. It cross-reacts with rat, hamster species. This monoclonal antibody proves valuable in disease research related to Pediatric Systemic Lupus Erythematosus and Dentin Dysplasia. The antibody can be utilized for detection of target protein by Western Blot (1/500-1/1000), Immunohistochemistry (1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RPTEC TERT1
Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27540/1789_G12_1_cr59549927dd49e_selected.jpg
❮
❯
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Hamster, Rat SPP1
- Species Reactivity
- Human, Hamster, Rat
- Applications
- Western Blot, Immunohistochemistry
- Conjugate
- Unconjugated, FITC
- Related Disease
- Pediatric Systemic Lupus Erythematosus and Dentin Dysplasia
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- Secreted Phosphoprotein 1; Early T-Lymphocyte Activation 1; Urinary Stone Protein; Nephropontin; Osteopontin; Uropontin; BNSP; OPN; Secreted Phosphoprotein 1 (Osteopontin, Bone Sialoprotein I, Early T-Lymphocyte Activation 1)
- Gene ID
- 6696
- UniProt ID
- P10451
- Sequence Similarities
- Belongs to the osteopontin family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Forms covalent cross-links mediated by transglutaminase TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers, increasing its collagen binding properties. (P10451-OSTP_HUMAN)
Extensively phosphorylated by FAM20C in the extracellular medium at multiple sites within the S-x-E/pS motif (PubMed:15869464, 22582013, 26091039).
The phosphorylated form inhibits hydroxyapatite crystallization.
Dephosphorylation via a mechanism involving ALPL/TNAP promotes hydroxyapatite crystallization (By similarity).
(P10451-OSTP_HUMAN)
O-glycosylated.
Isoform 5 is GalNAc O-glycosylated at Thr-59 or Ser-62.
- Protein Refseq
- NP_001035147.1; NP_001035149.1; NP_001238758.1; NP_001238759.1
- Function
- Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS3-FY2881. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "SPP1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1403z | Mouse Anti-SPP1 Recombinant Antibody (clone 23F4) | ELISA, ICC, IF, IHC, WB | Mouse IgG1 |
| MOB-1506CT | Recombinant Mouse anti-Human SPP1 Monoclonal antibody (EML2283) | WB | |
| HPAB-0068-YC | Human Anti-SPP1 Recombinant Antibody (clone h2K1) | FuncS | Humanized IgG |
| HPAB-0569-YJ | Human Anti-SPP1 Recombinant Antibody (clone OPN-3) | ELISA | Human IgG |
| FAMAB-1252CQ | Human Anti-SPP1 Recombinant Antibody (clone hu1A12) | WB, IF, ELISA, Inhib, Cyt | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0843CL | Anti-Human SPP1 Recombinant Antibody (2K1) | sELISA | |
| TAB-0844CL | Anti-Human SPP1 Recombinant Antibody (4C1) | sELISA | |
| TAB-0843CL-S(P) | Anti-Human SPP1 Recombinant Antibody scFv Fragment (2K1) | sELISA | |
| TAB-0844CL-S(P) | Anti-Human SPP1 Recombinant Antibody scFv Fragment (4C1) | sELISA | |
| TAB-0845CL-S(P) | Rabbit Anti-Spp1 Recombinant Antibody; scFv Fragment (TAB-0845CL-S(P)) | sELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0846CL | Anti-Human SPP1 Recombinant Antibody (MOR-6990) | ELISA, Neut | Human antibody |
| TAB-0847CL | Anti-Human SPP1 Recombinant Antibody (MOR-6991) | ELISA | Human antibody |
| TAB-0848CL | Anti-Human SPP1 Recombinant Antibody (MOR-6993) | ELISA, FuncS, Neut | Human antibody |
| TAB-0846CL-S(P) | Anti-Human SPP1 Recombinant Antibody scFv Fragment (MOR-6990) | ELISA | Human antibody |
| TAB-0847CL-S(P) | Anti-Human SPP1 Recombinant Antibody scFv Fragment (MOR-6991) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0814MZ | Chicken Anti-Osteopontin Polyclonal IgY | ELISA, IHC, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3394 | Hi-Affi™ Recombinant Rabbit Anti-SPP1 Monoclonal Antibody (DS3394AB) | FC, ICC, IF, IHC-P, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0068-YC-S(P) | Human Anti-SPP1 Recombinant Antibody (clone h2K1); scFv Fragment | FuncS | Humanized scFv |
| HPAB-0069-YC-S(P) | Human Anti-SPP1 Recombinant Antibody (clone c2K1); scFv Fragment | FuncS | Mouse scFv |
| HPAB-0070-YC-S(P) | Human Anti-SPP1 Recombinant Antibody (clone R2K1v1.7); scFv Fragment | ELISA | Humanized scFv |
| HPAB-1363-FY-F(E) | Mouse Anti-SPP1 Recombinant Antibody (clone 1A12); scFv Fragment | WB, ELISA | Mouse scFv |
| HPAB-0569-YJ-S(P) | Human Anti-SPP1 Recombinant Antibody (clone OPN-3); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0068-YC-F(E) | Human Anti-SPP1 Recombinant Antibody (clone h2K1); Fab Fragment | FuncS | Humanized Fab |
| HPAB-0069-YC-F(E) | Human Anti-SPP1 Recombinant Antibody (clone c2K1); Fab Fragment | FuncS | Human Fab |
| HPAB-1079WJ-F(E) | Human Anti-SPP1 Recombinant Antibody (clone MOR-6990); Fab Fragment | ELISA | Human Fab |
| HPAB-1080WJ-F(E) | Human Anti-SPP1 Recombinant Antibody (clone MOR-6991); Fab Fragment | ELISA | Human Fab |
| HPAB-1081WJ-F(E) | Human Anti-SPP1 Recombinant Antibody (clone MOR-6993); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY193 | Mouse Anti-SPP1 (clone 23C3) scFv-Fc Chimera | ELISA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6866 | Anti-SPP1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6867 | Anti-Mouse SPP1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC228 | Recombinant Anti-SPP1 (Thrombin x MMP cleavage site) Biparatopic Antibody, Tandem scFv (mAb 4-4-2 x mAb 7-5-4) | ELISA, WB | Tandem scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC299 | Recombinant Anti-SPP1 Eliminating Antibody, pH-Sensitive (hu1A12 var.) | Antigen-Sweeping In Vivo. | Human IgG1 |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
-4.jpg)
Application: FC, FuncS, IA, IF, IP, IHC
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Inhib, Cyt
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: Neut, ELISA, FuncS
-YJ-3.jpg)
Application: ELISA
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: WB, ELISA, Neut, FuncS
Application: FC, FuncS, IA, IF, IP, IHC
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Inhib, Cyt
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
