Human Anti-TPO Recombinant Antibody (clone TF3.5); Fab Fragment (CAT#: FAMAB-0036JF-F(E))
Recombinant monoclonal antibody can specifically bind TPO outside the immunodominant region. This human anti-non-IDR antibody TF3.5 can be potentially used in the treatment of patients with TPO autoantibody-positive Graves.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7987/21449_B_2_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7987/21449_B_2_5.jpg
Figure 2 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115705-TPO/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115705-TPO/subcellular
Specifications
- Host Species
- Human
- Derivation
- Human phage display Fab library
- Type
- Human Fab
- Specificity
- Human non-IDR TPO
- Species Reactivity
- Human
- Clone
- TF3.5
- Applications
- WB, ELISA, FuncS
- Related Disease
- TPO autoantibody-positive Graves
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Autoantibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-999 | Recombinant Anti-TPO Antibody | ELISA, WB, FuncS | IgG |
| MHH-999 | Recombinant Human Anti-TPO Antibody | WB, ELISA, IHC, FuncS | IgG |
| FAMAB-0364JF | Human Anti-TPO Recombinant Antibody (clone RI-34) | ELISA, FuncS | Human IgG |
| FAMAB-1281CQ | Human Anti-TPO Recombinant Antibody (clone WR1.7) | ELISA, Inhib | Human IgE |
| VS3-FY1477 | Recombinant Mouse Anti-TPO Antibody (clone 9G3-6F3-9B7) | IHC-P | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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